PMID- 25885797
OWN - NLM
STAT- MEDLINE
DCOM- 20160208
LR  - 20191210
IS  - 1873-4138 (Electronic)
IS  - 0309-1740 (Linking)
VI  - 106
DP  - 2015 Aug
TI  - A phase separation method for analyses of fluoroquinones in meats based on 
      ultrasound-assisted salt-induced liquid-liquid microextraction and a new 
      integrated device.
PG  - 61-8
LID - S0309-1740(15)00084-4 [pii]
LID - 10.1016/j.meatsci.2015.03.023 [doi]
AB  - Herein, we developed a novel integrated device to perform phase separation based 
      on ultrasound-assisted, salt-induced, liquid-liquid microextraction for 
      determination of five fluoroquinones in meats by HPLC analysis. The novel 
      integrated device consisted of three simple HDPE (high density polyethylene) 
      parts that were used to separate the solvent from the aqueous solution prior to 
      retrieving the extractant. The extraction parameters were optimized using the 
      response surface method based on central composite design: 589muL of acetone 
      solvent, pH2.1, 4.1min extraction time and 3.5g of Na2SO4. The limits of 
      detection were 0.056-0.64 mugkg(-1) and recoveries were 87.2-110.6% for the five 
      fluoroquinones in muscle tissue from fish, chicken, pork and beef. This method is 
      easily constructed from inexpensive materials, extraction efficiency is high, and 
      the approach is compatible with HPLC analysis. Thus, it has excellent prospects 
      for sample pre-treatment and analysis of fluoroquinones in meat samples.
CI  - Copyright (c) 2015 Elsevier Ltd. All rights reserved.
FAU - Wang, Huili
AU  - Wang H
AD  - College of Life Sciences, Wenzhou Medical University, Wenzhou 325035, China.
FAU - Gao, Ming
AU  - Gao M
AD  - College of Environmental Sciences and Public Health, Wenzhou Medical University, 
      Wenzhou 325035, China.
FAU - Xu, Youqu
AU  - Xu Y
AD  - College of Environmental Sciences and Public Health, Wenzhou Medical University, 
      Wenzhou 325035, China.
FAU - Wang, Wenwei
AU  - Wang W
AD  - College of Environmental Sciences and Public Health, Wenzhou Medical University, 
      Wenzhou 325035, China.
FAU - Zheng, Lian
AU  - Zheng L
AD  - College of Environmental Sciences and Public Health, Wenzhou Medical University, 
      Wenzhou 325035, China.
FAU - Dahlgren, Randy A
AU  - Dahlgren RA
AD  - Department of Land, Air and Water Resources, University of California, Davis, CA 
      95616, USA.
FAU - Wang, Xuedong
AU  - Wang X
AD  - College of Environmental Sciences and Public Health, Wenzhou Medical University, 
      Wenzhou 325035, China. Electronic address: zjuwxd@163.com.
LA  - eng
PT  - Comparative Study
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150403
PL  - England
TA  - Meat Sci
JT  - Meat science
JID - 101160862
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Fluoroquinolones)
RN  - 0 (Indicators and Reagents)
RN  - 0 (Solvents)
RN  - 0 (Sulfites)
RN  - 1364PS73AF (Acetone)
RN  - VTK01UQK3G (sodium sulfite)
SB  - IM
MH  - Acetone/chemistry
MH  - Animals
MH  - Anti-Bacterial Agents/*analysis/chemistry
MH  - Cattle
MH  - Chickens
MH  - China
MH  - Drug Residues/*analysis/chemistry
MH  - Feasibility Studies
MH  - Fishes
MH  - Fluoroquinolones/*analysis/chemistry
MH  - *Food Contamination
MH  - Food Inspection/instrumentation/*methods
MH  - Indicators and Reagents/chemistry
MH  - Limit of Detection
MH  - Liquid Phase Microextraction/instrumentation
MH  - Meat/*analysis
MH  - Seafood/*analysis
MH  - Solubility
MH  - Solvents/chemistry
MH  - Sulfites/chemistry
MH  - Sus scrofa
MH  - Ultrasonics
OTO - NOTNLM
OT  - Antibacterial agent analysis
OT  - Fluoroquinolones
OT  - Liquid-liquid microextraction
OT  - Meat
OT  - Salt-induced
OT  - Sample extraction
OT  - Ultrasound-assisted
EDAT- 2015/04/18 06:00
MHDA- 2016/02/09 06:00
CRDT- 2015/04/18 06:00
PHST- 2014/09/27 00:00 [received]
PHST- 2015/03/24 00:00 [revised]
PHST- 2015/03/26 00:00 [accepted]
PHST- 2015/04/18 06:00 [entrez]
PHST- 2015/04/18 06:00 [pubmed]
PHST- 2016/02/09 06:00 [medline]
AID - S0309-1740(15)00084-4 [pii]
AID - 10.1016/j.meatsci.2015.03.023 [doi]
PST - ppublish
SO  - Meat Sci. 2015 Aug;106:61-8. doi: 10.1016/j.meatsci.2015.03.023. Epub 2015 Apr 3.