PMID- 25886546 OWN - NLM STAT- MEDLINE DCOM- 20150821 LR - 20220408 IS - 0706-7437 (Print) IS - 1497-0015 (Electronic) IS - 0706-7437 (Linking) VI - 60 IP - 1 DP - 2015 Jan TI - Descriptive epidemiology of major depressive disorder in Canada in 2012. PG - 23-30 AB - OBJECTIVE: The epidemiology of major depressive disorder (MDD) was first described in the Canadian national population in 2002. Updated information is now available from a 2012 survey: the Canadian Community Health Study-Mental Health (CCHS-MH). METHOD: The CCHS-MH employed an adaptation of the World Health Organization World Mental Health Composite International Diagnostic Interview and had a sample of n=25 113. Demographic variables, treatment, comorbidities, suicidal ideation, and perceived stigma were assessed. The analysis estimated adjusted and unadjusted frequencies and prevalence ratios. All estimates incorporated analysis methods to account for complex survey design effects. RESULTS: The past-year prevalence of MDD was 3.9% (95% CI 3.5% to 4.2%). Prevalence was higher in women and in younger age groups. Among respondents with past-year MDD, 63.1% had sought treatment and 33.1% were taking an antidepressant (AD); 4.8% had past-year alcohol abuse and 4.5% had alcohol dependence. Among respondents with past-year MDD, the prevalence of cannabis abuse was 2.5% and that of dependence was 2.9%. For drugs other than cannabis, the prevalence of abuse was 2.3% and dependence was 2.9%. Generalized anxiety disorder was present in 24.9%. Suicide attempts were reported by 6.6% of respondents with past-year MDD. Among respondents accessing treatment, 37.5% perceived that others held negative opinions about them or treated them unfairly because of their disorder. CONCLUSIONS: MDD is a common, burdensome, and stigmatized condition in Canada. Seeking help from professionals was reported at a higher frequency than in prior Canadian studies, but there has been no increase in AD use among Canadians with MDD. FAU - Patten, Scott B AU - Patten SB AD - Professor, Departments of Community Health Sciences and Psychiatry, University of Calgary, Calgary, Alberta; Member, Mathison Centre for Mental Health Research & Education, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta. FAU - Williams, Jeanne V A AU - Williams JV AD - Research Associate, Department of Community Health Sciences, University of Calgary, Calgary, Alberta. FAU - Lavorato, Dina H AU - Lavorato DH AD - Research Associate, Department of Community Health Sciences, University of Calgary, Calgary, Alberta. FAU - Wang, Jian Li AU - Wang JL AD - Associate Professor, Departments of Community Health Sciences and Psychiatry, University of Calgary, Calgary, Alberta; Member, Mathison Centre for Mental Health Research & Education, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta. FAU - McDonald, Keltie AU - McDonald K AD - MSc Student, Department of Community Health Sciences, University of Calgary, Calgary, Alberta; Member, Mathison Centre for Mental Health Research & Education, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta. FAU - Bulloch, Andrew G M AU - Bulloch AG AD - Professor, Departments of Community Health Sciences and Psychiatry, University of Calgary, Calgary, Alberta; Member, Mathison Centre for Mental Health Research & Education, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta. LA - eng GR - mop-130415/Canadian Institutes of Health Research/Canada PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Can J Psychiatry JT - Canadian journal of psychiatry. Revue canadienne de psychiatrie JID - 7904187 RN - 0 (Antidepressive Agents) SB - IM EIN - Can J Psychiatry. 2015 Mar;60(3):95. PMID: 25886683 MH - Age Factors MH - Antidepressive Agents/*therapeutic use MH - Canada/epidemiology MH - Comorbidity MH - Demography MH - *Depressive Disorder, Major/epidemiology/psychology/therapy MH - Female MH - Humans MH - Male MH - Mental Health/statistics & numerical data MH - Middle Aged MH - Prevalence MH - Risk Factors MH - Socioeconomic Factors MH - Suicidal Ideation MH - *Suicide, Attempted/psychology/statistics & numerical data PMC - PMC4314053 EDAT- 2015/04/18 06:00 MHDA- 2015/08/22 06:00 PMCR- 2015/07/01 CRDT- 2015/04/18 06:00 PHST- 2014/05/01 00:00 [received] PHST- 2014/09/01 00:00 [accepted] PHST- 2015/04/18 06:00 [entrez] PHST- 2015/04/18 06:00 [pubmed] PHST- 2015/08/22 06:00 [medline] PHST- 2015/07/01 00:00 [pmc-release] AID - cjp-2015-vol60-january-23-30 [pii] AID - 10.1177/070674371506000106 [doi] PST - ppublish SO - Can J Psychiatry. 2015 Jan;60(1):23-30. doi: 10.1177/070674371506000106.