PMID- 25889742 OWN - NLM STAT- MEDLINE DCOM- 20151020 LR - 20181202 IS - 1477-7525 (Electronic) IS - 1477-7525 (Linking) VI - 13 DP - 2015 Apr 2 TI - Hamilton depression rating scale and montgomery-asberg depression rating scale in depressed and bipolar I patients: psychometric properties in a Brazilian sample. PG - 42 LID - 10.1186/s12955-015-0235-3 [doi] LID - 42 AB - BACKGROUND: The Hamilton Depression Rating Scale (HAM-D) and the Montgomery-Asberg Depression Scale (MADRS) are used worldwide and considered standard scales for evaluating depressive symptoms. This paper aims to investigate the psychometric proprieties (reliability and validity) of these scales in a Brazilian sample, and to compare responses in bipolar and unipolar patients. METHODS: The sample comprised 91 patients with either bipolar I or major depressive disorder from a psychiatric institute at Sao Paulo, Brazil. Participants were recruited and treated by clinicians through the Structured Interview for DSM-IV criteria, and had previously been interviewed by a trained, blind tester. RESULTS: Both scales indicated good reliability properties; however, the MADRS reliability statistics were higher than those of the HAM-D for detecting initial symptoms of unipolar depression. Correlation between the tests was moderate. Despite demonstrating adequate validity, neither test achieved the levels of sensitivity and specificity required for identification of a cutoff score to differentiate bipolar I and unipolar patients. CONCLUSIONS: Both scales demonstrate adequate reliability and validity for assessing depressive symptoms in the Brazilian sample, and are good options to complement psychiatric diagnosis, but are not appropriate for distinguishing between the two affective disorder types. FAU - Carneiro, Adriana Munhoz AU - Carneiro AM AD - Mood Disorders Unit (Grupo de Disturbios Afetivos- GRUDA), Department and Institute of Psychiatry, School of Medicine, Universidade de Sao Paulo (USP), Dr. Ovidio Pires de Campos St., 785 - 3rd floor -Ala Norte, Cerqueira Cesar, Sao Paulo, SP, Post code: 05403-010, Brazil. adrianacarneiro01@gmail.com. FAU - Fernandes, Fernando AU - Fernandes F AD - Mood Disorders Unit (Grupo de Disturbios Afetivos- GRUDA), Department and Institute of Psychiatry, School of Medicine, Universidade de Sao Paulo (USP), Dr. Ovidio Pires de Campos St., 785 - 3rd floor -Ala Norte, Cerqueira Cesar, Sao Paulo, SP, Post code: 05403-010, Brazil. fernandes2000@gmail.com. FAU - Moreno, Ricardo Alberto AU - Moreno RA AD - Mood Disorders Unit (Grupo de Disturbios Afetivos- GRUDA), Department and Institute of Psychiatry, School of Medicine, Universidade de Sao Paulo (USP), Dr. Ovidio Pires de Campos St., 785 - 3rd floor -Ala Norte, Cerqueira Cesar, Sao Paulo, SP, Post code: 05403-010, Brazil. ricardoalbertomoreno@gmail.com. LA - eng PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20150402 PL - England TA - Health Qual Life Outcomes JT - Health and quality of life outcomes JID - 101153626 SB - IM MH - Adolescent MH - Adult MH - Bipolar Disorder/*diagnosis MH - Brazil MH - Depression/*diagnosis MH - Depressive Disorder, Major/*diagnosis MH - Diagnosis, Differential MH - *Diagnostic and Statistical Manual of Mental Disorders MH - Female MH - Humans MH - Middle Aged MH - Mood Disorders/diagnosis MH - *Psychiatric Status Rating Scales MH - Psychometrics/*instrumentation MH - Quality of Life MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Young Adult PMC - PMC4391145 EDAT- 2015/04/19 06:00 MHDA- 2015/10/21 06:00 PMCR- 2015/04/02 CRDT- 2015/04/19 06:00 PHST- 2014/08/03 00:00 [received] PHST- 2015/03/11 00:00 [accepted] PHST- 2015/04/19 06:00 [entrez] PHST- 2015/04/19 06:00 [pubmed] PHST- 2015/10/21 06:00 [medline] PHST- 2015/04/02 00:00 [pmc-release] AID - 10.1186/s12955-015-0235-3 [pii] AID - 235 [pii] AID - 10.1186/s12955-015-0235-3 [doi] PST - epublish SO - Health Qual Life Outcomes. 2015 Apr 2;13:42. doi: 10.1186/s12955-015-0235-3.