PMID- 25890441
OWN - NLM
STAT- MEDLINE
DCOM- 20150826
LR  - 20181202
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1396
DP  - 2015 May 29
TI  - Water-compatible magnetic imprinted nanoparticles served as solid-phase 
      extraction sorbents for selective determination of trace 17beta-estradiol in 
      environmental water samples by liquid chromatography.
PG  - 7-16
LID - S0021-9673(15)00522-1 [pii]
LID - 10.1016/j.chroma.2015.03.083 [doi]
AB  - Endocrine disrupting compounds (EDCs) are a potential risk for wildlife and 
      humans for their existence in water. The efficient extraction and clean-up steps 
      are required before detection of low concentration levels of EDCs. In this work, 
      a novel water-compatible magnetic molecularly imprinted nanoparticles is 
      synthesized for the selective extraction of 17beta-estradiol (E2) in environmental 
      water samples. The preparation is carried out by introducing aldehyde groups to 
      the surface of amino-functionalized magnetic nanoparticles through a simple 
      one-step modification, followed by copolymerization of functional monomer gelatin 
      and template E2 via surface imprinting technique. The gelatin with abundant 
      active groups could not only act as functional monomer reacting with template, 
      but also assemble covalently at the surface of magnetic nanoparticles. At the 
      same time, gelatin would improve the water-compatibility of imprinted materials 
      for attaining high extraction efficiency. To obtain high imprinting effect, the 
      preparation conditions are optimized in detail using Central composite 
      design-response surface methodology. The resultant polymers have uniform 
      spherical shape with a shell thickness of about 8nm, stable crystalline form, and 
      super-paramagnetic property. Meanwhile, the obtained polymers have high capacity 
      of 12.87mgg(-1) and satisfactory selectivity to template molecule. To testify the 
      feasibility of the magnetic imprinted polymers in sample pretreatment, a method 
      for determination of trace E2 in environmental water samples was set up by 
      combination of solid-phase extraction (SPE) using the prepared polymers as 
      sorbents and HPLC for rapid isolation and determination of E2. The limit of 
      detection of proposed method is 0.04ngmL(-1), the intra- and inter-day relative 
      standard deviations (RSDs) are less than 4.6% and 5.7%, respectively. The 
      recoveries of E2 from environmental water samples are in the range from 88.3% to 
      99.1% with the RSDs less than 7.2%.
CI  - Copyright (c) 2015 Elsevier B.V. All rights reserved.
FAU - Hao, Yi
AU  - Hao Y
AD  - Institute of Analytical Science, Xi'an Jiaotong University, Xi'an 710049, China.
FAU - Gao, Ruixia
AU  - Gao R
AD  - Institute of Analytical Science, Xi'an Jiaotong University, Xi'an 710049, China. 
      Electronic address: ruixiagao@mail.xjtu.edu.cn.
FAU - Shi, Lu
AU  - Shi L
AD  - Institute of Analytical Science, Xi'an Jiaotong University, Xi'an 710049, China.
FAU - Liu, Dechun
AU  - Liu D
AD  - Department of Hepatobiliary Surgery, First Hospital of Xi'an Jiaotong University, 
      China.
FAU - Tang, Yuhai
AU  - Tang Y
AD  - Institute of Analytical Science, Xi'an Jiaotong University, Xi'an 710049, China.
FAU - Guo, Zengjun
AU  - Guo Z
AD  - Institute of Analytical Science, Xi'an Jiaotong University, Xi'an 710049, China. 
      Electronic address: guozj@mail.xjtu.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150407
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Chlorides)
RN  - 0 (Ferric Compounds)
RN  - 0 (Magnetite Nanoparticles)
RN  - 0 (Polymers)
RN  - 0 (Water Pollutants, Chemical)
RN  - 059QF0KO0R (Water)
RN  - 4TI98Z838E (Estradiol)
RN  - 9000-70-8 (Gelatin)
RN  - U38V3ZVV3V (ferric chloride)
SB  - IM
MH  - Chlorides/chemistry
MH  - Chromatography, High Pressure Liquid
MH  - Estradiol/*analysis/chemistry
MH  - Ferric Compounds/chemistry
MH  - Gelatin/chemistry
MH  - Humans
MH  - Magnetic Phenomena
MH  - Magnetite Nanoparticles/*chemistry
MH  - Molecular Imprinting
MH  - Polymers/chemistry
MH  - Solid Phase Extraction/*instrumentation/methods
MH  - Water/*chemistry
MH  - Water Pollutants, Chemical/*analysis
OTO - NOTNLM
OT  - Magnetic separation
OT  - Solid-phase extraction
OT  - Surface imprinting technique
OT  - Trace detection
OT  - Water compatibility
EDAT- 2015/04/22 06:00
MHDA- 2015/08/27 06:00
CRDT- 2015/04/20 06:00
PHST- 2015/02/09 00:00 [received]
PHST- 2015/03/30 00:00 [revised]
PHST- 2015/03/31 00:00 [accepted]
PHST- 2015/04/20 06:00 [entrez]
PHST- 2015/04/22 06:00 [pubmed]
PHST- 2015/08/27 06:00 [medline]
AID - S0021-9673(15)00522-1 [pii]
AID - 10.1016/j.chroma.2015.03.083 [doi]
PST - ppublish
SO  - J Chromatogr A. 2015 May 29;1396:7-16. doi: 10.1016/j.chroma.2015.03.083. Epub 
      2015 Apr 7.