PMID- 25891944 OWN - NLM STAT- MEDLINE DCOM- 20151006 LR - 20220321 IS - 1531-4995 (Electronic) IS - 0023-852X (Linking) VI - 125 IP - 8 DP - 2015 Aug TI - The predictive value of the preoperative Sinonasal Outcome Test-22 score in patients undergoing endoscopic sinus surgery for chronic rhinosinusitis. PG - 1779-84 LID - 10.1002/lary.25318 [doi] AB - OBJECTIVES/HYPOTHESIS: With the aim of facilitating preference-sensitive decision making regarding elective endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS), we set out to evaluate the predictive value of the 22-item Sinonasal Outcome Test (SNOT-22) patient-reported outcome measure and to compare outcomes of a UK cohort with a similar United States/Canadian-based study. STUDY DESIGN: Prospective observational cohort study, METHODS: Patients electing ESS in 87 UK hospitals were enrolled. The primary outcome was change in SNOT-22 score 3 months after surgery. Patients were categorized according to baseline SNOT-22 score, and the proportion of patients achieving a SNOT-22 minimal clinically important difference (MCID) of 8.9 was calculated, as well as the percentage change in SNOT-22 score. RESULTS: A total of 2,263 patients were included within this study. There was an average 40% reduction in SNOT-22 scores following surgery, and 66% of patients overall achieved the MCID. The proportion of patients achieving the MCID increased significantly with increasing baseline SNOT-22. Patients with a preoperative score of <20 failed to achieve a mean improvement greater than the MCID. Patients with a score of >30 had a greater than 70% chance of achieving the MCID. CRS patients with polyps had greater improvement than patients with CRS without polyps. The predictive value of the SNOT-22 is similar in the UK cohort, although overall patients did not benefit from surgery as much as their North American counterparts. CONCLUSIONS: Medically recalcitrant patients with CRS considering surgery should make decisions guided by their preoperative quality-of-life impairment, as measured by the SNOT-22. LEVEL OF EVIDENCE: 2b CI - (c) 2015 The American Laryngological, Rhinological and Otological Society, Inc. FAU - Hopkins, Claire AU - Hopkins C AD - Department of Otolaryngology, Guy's and St. Thomas' National Health Service Trust, London, United Kingdom. FAU - Rudmik, Luke AU - Rudmik L AD - Division of Otolaryngology-Head and Neck Surgery, Richmond Road Diagnostic and Treatment Centre, University of Calgary, Calgary, Alberta, Canada. FAU - Lund, Valerie J AU - Lund VJ AD - Department of Otolaryngology, Royal National Throat Nose & Ear Hospital, London, United Kingdom. LA - eng PT - Journal Article PT - Multicenter Study PT - Observational Study PT - Research Support, Non-U.S. Gov't DEP - 20150417 PL - United States TA - Laryngoscope JT - The Laryngoscope JID - 8607378 SB - IM MH - Adult MH - Chronic Disease MH - Endoscopy/*methods MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - *Otorhinolaryngologic Surgical Procedures MH - Predictive Value of Tests MH - Preoperative Period MH - Prospective Studies MH - Rhinitis/diagnosis/*surgery MH - Severity of Illness Index MH - Sinusitis/diagnosis/*surgery OTO - NOTNLM OT - Chronic rhinosinusitis OT - Sinonasal Outcome Test-22 OT - endoscopic sinus surgery OT - outcomes EDAT- 2015/04/22 06:00 MHDA- 2015/10/07 06:00 CRDT- 2015/04/21 06:00 PHST- 2015/03/16 00:00 [accepted] PHST- 2015/04/21 06:00 [entrez] PHST- 2015/04/22 06:00 [pubmed] PHST- 2015/10/07 06:00 [medline] AID - 10.1002/lary.25318 [doi] PST - ppublish SO - Laryngoscope. 2015 Aug;125(8):1779-84. doi: 10.1002/lary.25318. Epub 2015 Apr 17.