PMID- 25892068
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150612
LR  - 20150420
IS  - 1873-4324 (Electronic)
IS  - 0003-2670 (Linking)
VI  - 872
DP  - 2015 May 4
TI  - Extensible automated dispersive liquid-liquid microextraction.
PG  - 46-54
LID - S0003-2670(15)00285-8 [pii]
LID - 10.1016/j.aca.2015.02.061 [doi]
AB  - In this study, a convenient and extensible automated ionic liquid-based in situ 
      dispersive liquid-liquid microextraction (automated IL-based in situ DLLME) was 
      developed. 1-Octyl-3-methylimidazolium bis[(trifluoromethane)sulfonyl]imide 
      ([C8MIM]NTf2) is formed through the reaction between [C8MIM]Cl and lithium 
      bis[(trifluoromethane)sulfonyl]imide (LiNTf2) to extract the analytes. Using a 
      fully automatic SPE workstation, special SPE columns packed with nonwoven 
      polypropylene (NWPP) fiber, and a modified operation program, the procedures of 
      the IL-based in situ DLLME, including the collection of a water sample, injection 
      of an ion exchange solvent, phase separation of the emulsified solution, elution 
      of the retained extraction phase, and collection of the eluent into vials, can be 
      performed automatically. The developed approach, coupled with high-performance 
      liquid chromatography-diode array detection (HPLC-DAD), was successfully applied 
      to the detection and concentration determination of benzoylurea (BU) insecticides 
      in water samples. Parameters affecting the extraction performance were 
      investigated and optimized. Under the optimized conditions, the proposed method 
      achieved extraction recoveries of 80% to 89% for water samples. The limits of 
      detection (LODs) of the method were in the range of 0.16-0.45 ng mL(-1). The 
      intra-column and inter-column relative standard deviations (RSDs) were <8.6%. 
      Good linearity (r>0.9986) was obtained over the calibration range from 2 to 500 
      ng mL(-1). The proposed method opens a new avenue for automated DLLME that not 
      only greatly expands the range of viable extractants, especially functional ILs 
      but also enhances its application for various detection methods. Furthermore, 
      multiple samples can be processed simultaneously, which accelerates the sample 
      preparation and allows the examination of a large number of samples.
CI  - Copyright (c) 2015 Elsevier B.V. All rights reserved.
FAU - Li, Songqing
AU  - Li S
AD  - Department of Applied Chemistry, China Agricultural University, Yuanmingyuan West 
      Road 2#, Haidian District, Beijing 100193, China.
FAU - Hu, Lu
AU  - Hu L
AD  - Department of Applied Chemistry, China Agricultural University, Yuanmingyuan West 
      Road 2#, Haidian District, Beijing 100193, China.
FAU - Chen, Ketao
AU  - Chen K
AD  - Department of Applied Chemistry, China Agricultural University, Yuanmingyuan West 
      Road 2#, Haidian District, Beijing 100193, China.
FAU - Gao, Haixiang
AU  - Gao H
AD  - Department of Applied Chemistry, China Agricultural University, Yuanmingyuan West 
      Road 2#, Haidian District, Beijing 100193, China. Electronic address: 
      hxgao@cau.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20150227
PL  - Netherlands
TA  - Anal Chim Acta
JT  - Analytica chimica acta
JID - 0370534
OTO - NOTNLM
OT  - Automated dispersive liquid-liquid microextraction
OT  - Benzoylurea insecticides
OT  - Fully automatic SPE workstation
OT  - Ionic liquid
OT  - Nonwoven polypropylene fiber
EDAT- 2015/04/22 06:00
MHDA- 2015/04/22 06:01
CRDT- 2015/04/21 06:00
PHST- 2014/11/12 00:00 [received]
PHST- 2015/01/19 00:00 [revised]
PHST- 2015/02/25 00:00 [accepted]
PHST- 2015/04/21 06:00 [entrez]
PHST- 2015/04/22 06:00 [pubmed]
PHST- 2015/04/22 06:01 [medline]
AID - S0003-2670(15)00285-8 [pii]
AID - 10.1016/j.aca.2015.02.061 [doi]
PST - ppublish
SO  - Anal Chim Acta. 2015 May 4;872:46-54. doi: 10.1016/j.aca.2015.02.061. Epub 2015 
      Feb 27.