PMID- 25897351
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150421
LR  - 20231104
IS  - 1948-9358 (Print)
IS  - 1948-9358 (Electronic)
IS  - 1948-9358 (Linking)
VI  - 6
IP  - 3
DP  - 2015 Apr 15
TI  - Gut microbiota and Ma-Pi 2 macrobiotic diet in the treatment of type 2 diabetes.
PG  - 403-11
LID - 10.4239/wjd.v6.i3.403 [doi]
AB  - In the past 10 years the prevalence of type 2 diabetes mellitus (T2DM) has 
      increased hugely worldwide, driven by a rise in the numbers of overweight and 
      obese individuals. A number of diets have been shown to be effective for the 
      management of T2DM: the Mediterranean diet, the vegetarian diet and the 
      low-calorie diet. Results of studies clearly indicate, however, that the efficacy 
      of these diets is not solely related to the biochemical structure of the 
      individual nutrients they contain. This review discusses this point with 
      reference to the potential role of the intestinal microbiota in diabetes. The 
      macrobiotic Ma-Pi 2 diet is rich in carbohydrates, whole grains and vegetables, 
      with no animal fat or protein or added sugar. In short- and medium-term trials 
      conducted in patients with T2DM, the Ma-Pi 2 diet has been found to significantly 
      improve indicators of metabolic control, including fasting blood glucose, 
      glycosylated hemoglobin, the serum lipid profile, body mass index, body weight 
      and blood pressure. The diet may also alter the gut microbiota composition, which 
      could additionally affect glycemic control. As a result, the Ma-Pi 2 diet could 
      be considered a valid additional short- to medium-term treatment for T2DM.
FAU - Fallucca, Francesco
AU  - Fallucca F
AD  - Francesco Fallucca, "In Unam Sapientiam" Foundation, University La Sapienza, 
      00161 Rome, Italy.
FAU - Fontana, Lucia
AU  - Fontana L
AD  - Francesco Fallucca, "In Unam Sapientiam" Foundation, University La Sapienza, 
      00161 Rome, Italy.
FAU - Fallucca, Sara
AU  - Fallucca S
AD  - Francesco Fallucca, "In Unam Sapientiam" Foundation, University La Sapienza, 
      00161 Rome, Italy.
FAU - Pianesi, Mario
AU  - Pianesi M
AD  - Francesco Fallucca, "In Unam Sapientiam" Foundation, University La Sapienza, 
      00161 Rome, Italy.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - World J Diabetes
JT  - World journal of diabetes
JID - 101547524
PMC - PMC4398897
OTO - NOTNLM
OT  - Gut microbiota
OT  - Low-grade inflammation
OT  - Ma-Pi 2 macrobiotic diet
OT  - Metabolic control
OT  - Type 2 diabetes
EDAT- 2015/04/22 06:00
MHDA- 2015/04/22 06:01
PMCR- 2015/04/15
CRDT- 2015/04/22 06:00
PHST- 2014/08/28 00:00 [received]
PHST- 2015/01/10 00:00 [revised]
PHST- 2015/01/30 00:00 [accepted]
PHST- 2015/04/22 06:00 [entrez]
PHST- 2015/04/22 06:00 [pubmed]
PHST- 2015/04/22 06:01 [medline]
PHST- 2015/04/15 00:00 [pmc-release]
AID - 10.4239/wjd.v6.i3.403 [doi]
PST - ppublish
SO  - World J Diabetes. 2015 Apr 15;6(3):403-11. doi: 10.4239/wjd.v6.i3.403.