PMID- 25899437
OWN - NLM
STAT- MEDLINE
DCOM- 20160509
LR  - 20160511
IS  - 2042-6984 (Electronic)
IS  - 2042-6976 (Linking)
VI  - 5
IP  - 8
DP  - 2015 Aug
TI  - Impact of allergic rhinitis on quality of life after adenotonsillectomy for 
      pediatric sleep-disordered breathing.
PG  - 741-6
LID - 10.1002/alr.21529 [doi]
AB  - BACKGROUND: Adenotonsillar hypertrophy is an undisputed major contributor to the 
      development of pediatric sleep-disordered breathing (SDB). However, some children 
      with SDB have experienced a worsening of quality of life (QOL) after 
      adenotonsillectomy. The purpose of this study was to identify the factors of 
      deteriorating QOL after adenotonsillectomy. METHODS: This was an observational 
      cohort study at a single institute and consisted of 70 children with SDB who 
      underwent adenotonsillectomy. The QOL was evaluated using the 18-item 
      quality-of-life survey for obstructive sleep apnea (OSA-18) prior to surgery 
      (S1), and at 1 month (S2), 6 months (S3), and 12 months (S4) postoperatively. 
      Deterioration of QOL was defined as an increase in total scores of S3 and/or S4 
      by more than 25% of those on S2. Patients were categorized into 
      rhinitis/nonrhinitis and atopy/non-atopy using the nasal symptom questionnaire 
      and skin-prick test, respectively. RESULTS: The mean total scores of S2 and S4 
      were significantly lower than those of S1 (p < 0.001); however, some patients (n 
      = 27, 38.6%) experienced an increase in scores. Patients with worsened QOL showed 
      higher total immunoglobulin E (IgE) levels (p = 0.034) and complained of a 
      rhinitis symptom more frequently (p = 0.039). Children with atopy were more 
      likely to experience deterioration of QOL than those without (p = 0.004). In 
      addition, multivariate logistic regression analysis showed that allergic rhinitis 
      (AR) was a predictor for deterioration of QOL. CONCLUSION: This study suggests 
      that AR may be a risk factor for deterioration of long-term QOL after 
      adenotonsillectomy. Therefore, preoperative evaluation and proper management of 
      AR might be considered in pediatric SDB.
CI  - (c) 2015 ARS-AAOA, LLC.
FAU - Kim, Dong-Kyu
AU  - Kim DK
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Chuncheon Sacred Heart 
      Hospital, Hallym University College of Medicine, Chuncheon, Korea.
FAU - Han, Doo Hee
AU  - Han DH
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National 
      University College of Medicine, Seoul, Korea.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20150421
PL  - United States
TA  - Int Forum Allergy Rhinol
JT  - International forum of allergy & rhinology
JID - 101550261
SB  - IM
MH  - *Adenoidectomy
MH  - Adolescent
MH  - Child
MH  - Child, Preschool
MH  - Disease Progression
MH  - Female
MH  - Humans
MH  - Male
MH  - Postoperative Complications/*etiology
MH  - Preoperative Care
MH  - *Quality of Life
MH  - Rhinitis, Allergic/*complications
MH  - Sleep Apnea, Obstructive/complications/*surgery
MH  - *Tonsillectomy
OTO - NOTNLM
OT  - adenoidectomy
OT  - allergic rhinitis
OT  - child
OT  - quality of life
OT  - sleep-disordered breathing
OT  - tonsillectomy
EDAT- 2015/04/23 06:00
MHDA- 2016/05/10 06:00
CRDT- 2015/04/23 06:00
PHST- 2014/10/02 00:00 [received]
PHST- 2015/02/06 00:00 [revised]
PHST- 2015/02/26 00:00 [accepted]
PHST- 2015/04/23 06:00 [entrez]
PHST- 2015/04/23 06:00 [pubmed]
PHST- 2016/05/10 06:00 [medline]
AID - 10.1002/alr.21529 [doi]
PST - ppublish
SO  - Int Forum Allergy Rhinol. 2015 Aug;5(8):741-6. doi: 10.1002/alr.21529. Epub 2015 
      Apr 21.