PMID- 25899766
OWN - NLM
STAT- MEDLINE
DCOM- 20160225
LR  - 20181113
IS  - 1573-2584 (Electronic)
IS  - 0301-1623 (Linking)
VI  - 47
IP  - 6
DP  - 2015 Jun
TI  - Prospective study of depression among dialysis patients in Saudi Arabia.
PG  - 1001-10
LID - 10.1007/s11255-015-0977-1 [doi]
AB  - OBJECTIVES: The purpose was to determine the short-term course of depression 
      among dialysis patients in Saudi Arabia and identify baseline characteristics 
      that may influence course. METHODS: Thirty-nine dialysis patients in Jeddah, SA, 
      were identified with subthreshold, minor, or major depressive disorders using the 
      Structured Clinical Interview for Depression (SCID) and followed up at 6 and 12 
      weeks using the Longitudinal Interview and Follow-up Evaluation (LIFE) schedule. 
      Depressive symptoms were tracked using the Hamilton Depression Rating Scale 
      (HDRS). Patient characteristics measured at baseline included demographic, 
      psychosocial, physical health, and treatment factors. RESULTS: Of the 20 patients 
      with major or minor depressive disorder, eight (40 %) fully remitted by 6 weeks 
      and an additional three patients remitted over the next 6 weeks, leaving 45 % 
      with significant depressive symptoms persisting beyond 12 weeks. Subthreshold 
      disorders followed a similar course (42 % with persistent symptoms). Few patients 
      received treatment for depression. Those with more education, severe health 
      problems, poorer psychological function, more severe depressive symptoms, or a 
      family psychiatric history were less likely to remit. Similar factors predicted 
      change in depressive symptoms assessed by HDRS, especially high medical 
      co-morbidity, severe illness, and overall poor psychological functioning. 
      CONCLUSIONS: Nearly one-half of depressed dialysis patients in Saudi Arabia 
      continue to have significant symptoms beyond 12 weeks of follow-up, few of whom 
      were treated. Specific characteristics at baseline identify depressed dialysis 
      patients at greater risk of persistent symptoms who need treatment.
FAU - Al Zaben, Faten
AU  - Al Zaben F
AD  - Psychiatry Division, Department of Medicine, King Abdulaziz University, Jeddah, 
      Saudi Arabia.
FAU - Sehlo, Mohammad Gamal
AU  - Sehlo MG
FAU - Khalifa, Doaa Ahmed
AU  - Khalifa DA
FAU - Al Shohaib, Saad
AU  - Al Shohaib S
FAU - Shaheen, Faisul
AU  - Shaheen F
FAU - Alzaben, Linda
AU  - Alzaben L
FAU - Ahmad, Rami Ghazi
AU  - Ahmad RG
FAU - Ashy, Jafar Ayman
AU  - Ashy JA
FAU - Felemban, Reema Ghazi
AU  - Felemban RG
FAU - Koenig, Harold G
AU  - Koenig HG
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150422
PL  - Netherlands
TA  - Int Urol Nephrol
JT  - International urology and nephrology
JID - 0262521
SB  - IM
MH  - Depression/*epidemiology
MH  - Depressive Disorder/*epidemiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Renal Dialysis/*psychology
MH  - Saudi Arabia
EDAT- 2015/04/23 06:00
MHDA- 2016/02/26 06:00
CRDT- 2015/04/23 06:00
PHST- 2015/02/22 00:00 [received]
PHST- 2015/04/06 00:00 [accepted]
PHST- 2015/04/23 06:00 [entrez]
PHST- 2015/04/23 06:00 [pubmed]
PHST- 2016/02/26 06:00 [medline]
AID - 10.1007/s11255-015-0977-1 [doi]
PST - ppublish
SO  - Int Urol Nephrol. 2015 Jun;47(6):1001-10. doi: 10.1007/s11255-015-0977-1. Epub 
      2015 Apr 22.