PMID- 25904156
OWN - NLM
STAT- MEDLINE
DCOM- 20161213
LR  - 20220317
IS  - 1931-7565 (Electronic)
IS  - 1931-7557 (Linking)
VI  - 10
IP  - 1
DP  - 2016 Mar
TI  - Static and dynamic posterior cingulate cortex nodal topology of default mode 
      network predicts attention task performance.
PG  - 212-25
LID - 10.1007/s11682-015-9384-6 [doi]
AB  - Characterization of the default mode network (DMN) as a complex network of 
      functionally interacting dynamic systems has received great interest for the 
      study of DMN neural mechanisms. In particular, understanding the relationship of 
      intrinsic resting-state DMN brain network with cognitive behaviors is an 
      important issue in healthy cognition and mental disorders. However, it is still 
      unclear how DMN functional connectivity links to cognitive behaviors during 
      resting-state. In this study, we hypothesize that static and dynamic DMN nodal 
      topology is associated with upcoming cognitive task performance. We used graph 
      theory analysis in order to understand better the relationship between the DMN 
      functional connectivity and cognitive behavior during resting-state and task 
      performance. Nodal degree of the DMN was calculated as a metric of network 
      topology. We found that the static and dynamic posterior cingulate cortex (PCC) 
      nodal degree within the DMN was associated with task performance (Reaction Time). 
      Our results show that the core node PCC nodal degree within the DMN was 
      significantly correlated with reaction time, which suggests that the PCC plays a 
      key role in supporting cognitive function.
FAU - Lin, Pan
AU  - Lin P
AD  - Key Laboratory of Biomedical Information Engineering of Education Ministry, 
      Institute of Biomedical Engineering, Xi'an Jiaotong University, Xi'an, 710049, 
      China. linpan@mail.xjtu.edu.cn.
AD  - Center for Mind/Brain Sciences, University of Trento, Mattarello, 38100, Italy. 
      linpan@mail.xjtu.edu.cn.
AD  - Brain Imaging Center, McLean Hospital, Department of Psychiatry, Harvard Medical 
      School, Belmont, MA, USA. linpan@mail.xjtu.edu.cn.
FAU - Yang, Yong
AU  - Yang Y
AD  - School of Information Technology, Jiangxi University of Finance and Economics, 
      Nanchang, People's Republic of China.
FAU - Jovicich, Jorge
AU  - Jovicich J
AD  - Center for Mind/Brain Sciences, University of Trento, Mattarello, 38100, Italy.
AD  - Department of Cognitive and Education Sciences, University of Trento, Rovereto, 
      38068, Italy.
FAU - De Pisapia, Nicola
AU  - De Pisapia N
AD  - Center for Mind/Brain Sciences, University of Trento, Mattarello, 38100, Italy.
FAU - Wang, Xiang
AU  - Wang X
AD  - Medical Psychological Institute of Second Xiangya Hospital, Central South 
      University, Changsha, China.
FAU - Zuo, Chun S
AU  - Zuo CS
AD  - Brain Imaging Center, McLean Hospital, Department of Psychiatry, Harvard Medical 
      School, Belmont, MA, USA.
FAU - Levitt, James Jonathan
AU  - Levitt JJ
AD  - Clinical Neuroscience Division, Laboratory of Neuroscience, Department of 
      Psychiatry, VA, Boston Healthcare System, Brockton Division, Harvard Medical 
      School, Boston, MA, 02301, USA.
AD  - Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham & Women's 
      Hospital, Harvard Medical School, Boston, MA, 02215, USA.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Brain Imaging Behav
JT  - Brain imaging and behavior
JID - 101300405
SB  - IM
MH  - Adult
MH  - Attention/*physiology
MH  - Brain Mapping/methods
MH  - Gyrus Cinguli/*physiology
MH  - Humans
MH  - Magnetic Resonance Imaging/methods
MH  - Neural Pathways/physiology
MH  - Neuropsychological Tests
MH  - Reaction Time
MH  - Rest
MH  - Young Adult
OTO - NOTNLM
OT  - Default mode network (DMN)
OT  - Degree
OT  - Functional connectivity (FC)
OT  - Posterior cingulate cortex (PCC)
OT  - Task performance
EDAT- 2015/04/24 06:00
MHDA- 2016/12/15 06:00
CRDT- 2015/04/24 06:00
PHST- 2015/04/24 06:00 [entrez]
PHST- 2015/04/24 06:00 [pubmed]
PHST- 2016/12/15 06:00 [medline]
AID - 10.1007/s11682-015-9384-6 [pii]
AID - 10.1007/s11682-015-9384-6 [doi]
PST - ppublish
SO  - Brain Imaging Behav. 2016 Mar;10(1):212-25. doi: 10.1007/s11682-015-9384-6.