PMID- 25911904
OWN - NLM
STAT- MEDLINE
DCOM- 20150609
LR  - 20151119
IS  - 0172-6390 (Print)
IS  - 0172-6390 (Linking)
VI  - 62
IP  - 137
DP  - 2015 Jan-Feb
TI  - Glycemic changes after gastrectomy in non-morbidly obese patients with gastric 
      cancer and diabetes.
PG  - 245-50
AB  - BACKGROUND/AIMS: To evaluate the glycemic changes after gastrectomy in 
      non-morbidly obese patients with gastric cancer (GC) and type 2 diabetes mellitus 
      (T2DM). METHODOLOGY: Between December 2011 and June 2014, we included 46 patients 
      with gastric cancer and T2DM of a body mass index (BMI) < 30 kg/m2, who underwent 
      gastrectomy in our center. The comparisons of FPGs in specific periods were 
      performed according to age, extent of gastrectomy, reconstruction type, 
      preoperative triglyceride (TG) level and so on. RESULTS: The non-morbidly obese 
      patients experienced an improvement of glycemic control. T2DM resolution happened 
      3 weeks after surgery. FPG decreased significantly after postoperative day 21 
      compared to preoperative FPG. 32 patients experienced DM improvement after 
      postoperative day 21. The age and relatively lower preoperative TG patients, who 
      underwent total gastrectomy (P<0.001) or duodenal bypass reconstruction (Billroth 
      II, Roux-en-Y gastrojejunostomy, or Roux-en-Y esophagojejunostomy, P=0.009) 
      appeared to have a better glycemic control. CONCLUSIONS: Our finding observed 
      through this simulation model suggested that non-morbidly obese patients may also 
      benefit from metabolic surgery for glycemic control, associated with age, extent 
      of gastrectomy, reconstruction type, and preoperative triglyceride level.
FAU - Shen, Zhiyong
AU  - Shen Z
FAU - Yu, Jiang
AU  - Yu J
FAU - Lei, Shangtong
AU  - Lei S
FAU - Mou, Tingyu
AU  - Mou T
FAU - Hu, Yanfeng
AU  - Hu Y
FAU - Liu, Hao
AU  - Liu H
FAU - Li, Guoxin
AU  - Li G
LA  - eng
PT  - Journal Article
PT  - Observational Study
PT  - Research Support, Non-U.S. Gov't
PL  - Greece
TA  - Hepatogastroenterology
JT  - Hepato-gastroenterology
JID - 8007849
RN  - 0 (Biomarkers)
RN  - 0 (Blood Glucose)
RN  - 0 (Triglycerides)
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Aged, 80 and over
MH  - Anastomosis, Roux-en-Y
MH  - Biomarkers/blood
MH  - Blood Glucose/*metabolism
MH  - Body Mass Index
MH  - China
MH  - Diabetes Mellitus, Type 2/*blood/complications/diagnosis
MH  - Esophagostomy
MH  - Fasting/blood
MH  - Female
MH  - *Gastrectomy
MH  - Gastroenterostomy
MH  - Humans
MH  - Jejunostomy
MH  - Male
MH  - Middle Aged
MH  - Obesity/*complications/diagnosis
MH  - Retrospective Studies
MH  - Stomach Neoplasms/complications/diagnosis/*surgery
MH  - Time Factors
MH  - Treatment Outcome
MH  - Triglycerides/blood
EDAT- 2015/04/29 06:00
MHDA- 2015/06/10 06:00
CRDT- 2015/04/28 06:00
PHST- 2015/04/28 06:00 [entrez]
PHST- 2015/04/29 06:00 [pubmed]
PHST- 2015/06/10 06:00 [medline]
PST - ppublish
SO  - Hepatogastroenterology. 2015 Jan-Feb;62(137):245-50.