PMID- 25916336
OWN - NLM
STAT- MEDLINE
DCOM- 20151203
LR  - 20181113
IS  - 1129-2377 (Electronic)
IS  - 1129-2369 (Print)
IS  - 1129-2369 (Linking)
VI  - 16
DP  - 2015
TI  - The effects of acupuncture treatment on the right frontoparietal network in 
      migraine without aura patients.
PG  - 518
LID - 10.1186/s10194-015-0518-4 [doi]
LID - 33
AB  - BACKGROUND: Functional and structural abnormalities in resting-state brain 
      networks in migraine patients have been confirmed by previous functional magnetic 
      resonance imaging (fMRI) studies. However, few studies focusing on the neural 
      responses of therapeutic treatment on migraine have been conducted. In this 
      study, we tried to examined the treatment-related effects of standard acupuncture 
      treatment on the right frontoparietal network (RFPN) in migraine patients. 
      METHODS: A total of 12 migraine without aura (MWoA) patients were recruited to 
      undergo resting-state fMRI scanning and were rescanned after 4 weeks standard 
      acupuncture treatment. Another 12 matched healthy control (HC) subjects underwent 
      once scanning for comparison. We analyzed the functional connectivity of the RFPN 
      between MWoA patients and HC subjects before treatment and that of the MWoA 
      patients before and after treatment. Diffusion tensor images (DTI) data analyzing 
      was also performed to detect fiber-related treatment responses. RESULTS: We 
      observed significantly decreased FC in the RFPN and that the decreased FC could 
      be reversed by acupuncture treatment. The changes of FC in MWoA patients was 
      negatively correlated with the decrease of visual analogue scale (VAS) scores 
      after treatment. This study indicated that acupuncture treatment for MWoA 
      patients was associated with normalizing effects on the intrinsic decreased FC of 
      the RFPN. CONCLUSIONS: Our study provided new insights into the treatment-related 
      neural responses in MWoA patients and suggested potential functional pathways for 
      the evaluation of treatment in MWoA patients. Future studies are still in need to 
      confirm the current results and to elucidate the complex neural mechanisms of 
      acupuncture treatment.
FAU - Li, Kuangshi
AU  - Li K
AD  - Department of Neurology and Stroke Center, Dongzhimen Hospital, The First 
      Affiliated Hospital of Beijing University of Chinese Medicine, Beijing, 100700, 
      China, likuangshi89@hotmail.com.
FAU - Zhang, Yong
AU  - Zhang Y
FAU - Ning, Yanzhe
AU  - Ning Y
FAU - Zhang, Hua
AU  - Zhang H
FAU - Liu, Hongwei
AU  - Liu H
FAU - Fu, Caihong
AU  - Fu C
FAU - Ren, Yi
AU  - Ren Y
FAU - Zou, Yihuai
AU  - Zou Y
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150418
PL  - England
TA  - J Headache Pain
JT  - The journal of headache and pain
JID - 100940562
SB  - IM
MH  - Acupuncture Therapy/*methods
MH  - Adult
MH  - Brain/pathology
MH  - Brain Mapping
MH  - Female
MH  - Frontal Lobe/*physiopathology
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Migraine without Aura/*therapy
MH  - Nerve Net/*physiopathology
MH  - Parietal Lobe/*physiopathology
MH  - Treatment Outcome
PMC - PMC4411327
EDAT- 2015/04/29 06:00
MHDA- 2015/12/15 06:00
PMCR- 2015/04/18
CRDT- 2015/04/29 06:00
PHST- 2015/03/20 00:00 [received]
PHST- 2015/04/14 00:00 [accepted]
PHST- 2015/04/29 06:00 [entrez]
PHST- 2015/04/29 06:00 [pubmed]
PHST- 2015/12/15 06:00 [medline]
PHST- 2015/04/18 00:00 [pmc-release]
AID - 518 [pii]
AID - 10.1186/s10194-015-0518-4 [doi]
PST - ppublish
SO  - J Headache Pain. 2015;16:518. doi: 10.1186/s10194-015-0518-4. Epub 2015 Apr 18.