PMID- 25917670
OWN - NLM
STAT- MEDLINE
DCOM- 20150914
LR  - 20150630
IS  - 1097-6817 (Electronic)
IS  - 0194-5998 (Linking)
VI  - 153
IP  - 1
DP  - 2015 Jul
TI  - Comparison of Socioeconomic and Demographic Factors in Patients with Chronic 
      Rhinosinusitis and Allergic Fungal Rhinosinusitis.
PG  - 137-43
LID - 10.1177/0194599815580978 [doi]
AB  - OBJECTIVE: The primary objective of this study is to evaluate the differences in 
      socioeconomic, demographic, and disease severity factors between patients with 
      chronic rhinosinusitis (CRS) and those with allergic fungal rhinosinusitis 
      (AFRS). STUDY DESIGN: A retrospective cohort analysis was performed. SETTING: The 
      study was conducted at the hospital of the University of North Carolina at Chapel 
      Hill. SUBJECTS AND METHODS: A total of 186 patients were included (93 AFRS, 93 
      CRS with and without nasal polyps). Socio- economic and demographic data were 
      obtained from the North Carolina State Data Center. Indicators of disease 
      severity were measured by Lund-Mackay scores, serum immunoglobulin E (IgE) 
      levels, diagnosis of asthma and/or allergic rhinitis, and the number of surgeries 
      and computed tomography scans performed. Associations were analyzed with Fisher's 
      exact, Wilcoxon rank sum, and Pearson's correlations tests. RESULTS: Compared 
      with patients with AFRS, patients in both CRS groups were predominantly white (P 
      < .0001), were older at the time of diagnosis (P < .0001), had higher 
      county-based income per capita (P = .004), had lower quantitative serum IgE level 
      (P < .001), and had lower Lund-Mackay scores (P < .0001). No associations between 
      disease severity, socioeconomic status, and demographic factors were found within 
      the CRS groups. CONCLUSION: Within our cohort of patients residing in North 
      Carolina, those with CRS have higher income, more access to primary care, and 
      lower markers of disease severity than those with AFRS. These data continue to 
      support the notion that AFRS merits classification as a distinct subtype of CRS.
CI  - (c) American Academy of Otolaryngology-Head and Neck Surgery Foundation 2015.
FAU - Lu-Myers, Yemeng
AU  - Lu-Myers Y
AD  - Department of Otolaryngology-Head and Neck Surgery, University of North Carolina, 
      Chapel Hill, North Carolina, USA.
FAU - Deal, Allison M
AU  - Deal AM
AD  - Department of Otolaryngology-Head and Neck Surgery, University of North Carolina, 
      Chapel Hill, North Carolina, USA.
FAU - Miller, Justin D
AU  - Miller JD
AD  - Department of Otolaryngology-Head and Neck Surgery, University of North Carolina, 
      Chapel Hill, North Carolina, USA.
FAU - Thorp, Brian D
AU  - Thorp BD
AD  - Department of Otolaryngology-Head and Neck Surgery, University of North Carolina, 
      Chapel Hill, North Carolina, USA.
FAU - Sreenath, Satyan B
AU  - Sreenath SB
AD  - Department of Otolaryngology-Head and Neck Surgery, University of North Carolina, 
      Chapel Hill, North Carolina, USA.
FAU - McClurg, Stanley M
AU  - McClurg SM
AD  - Department of Otolaryngology-Head and Neck Surgery, University of North Carolina, 
      Chapel Hill, North Carolina, USA.
FAU - Senior, Brent A
AU  - Senior BA
AD  - Department of Otolaryngology-Head and Neck Surgery, University of North Carolina, 
      Chapel Hill, North Carolina, USA.
FAU - Zanation, Adam M
AU  - Zanation AM
AD  - Department of Otolaryngology-Head and Neck Surgery, University of North Carolina, 
      Chapel Hill, North Carolina, USA.
FAU - Ebert, Charles S Jr
AU  - Ebert CS Jr
AD  - Department of Otolaryngology-Head and Neck Surgery, University of North Carolina, 
      Chapel Hill, North Carolina, USA cebert@med.unc.edu.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20150427
PL  - England
TA  - Otolaryngol Head Neck Surg
JT  - Otolaryngology--head and neck surgery : official journal of American Academy of 
      Otolaryngology-Head and Neck Surgery
JID - 8508176
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Chronic Disease
MH  - Demography
MH  - Female
MH  - Health Services Accessibility
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mycoses/complications/*epidemiology
MH  - Nasal Polyps/*complications
MH  - North Carolina
MH  - Retrospective Studies
MH  - Rhinitis, Allergic/*complications/*epidemiology
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - Sinusitis/*complications/*epidemiology
MH  - Socioeconomic Factors
MH  - Young Adult
OTO - NOTNLM
OT  - chronic rhinosinusitis
OT  - demography
OT  - epidemiology
OT  - fungus
OT  - gender
OT  - race
OT  - sinusitis
EDAT- 2015/04/29 06:00
MHDA- 2015/09/15 06:00
CRDT- 2015/04/29 06:00
PHST- 2014/12/18 00:00 [received]
PHST- 2015/03/18 00:00 [accepted]
PHST- 2015/04/29 06:00 [entrez]
PHST- 2015/04/29 06:00 [pubmed]
PHST- 2015/09/15 06:00 [medline]
AID - 0194599815580978 [pii]
AID - 10.1177/0194599815580978 [doi]
PST - ppublish
SO  - Otolaryngol Head Neck Surg. 2015 Jul;153(1):137-43. doi: 
      10.1177/0194599815580978. Epub 2015 Apr 27.