PMID- 25932307
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150501
LR  - 20220410
IS  - 2005-7806 (Print)
IS  - 2005-7814 (Electronic)
IS  - 2005-7806 (Linking)
VI  - 7
IP  - 2
DP  - 2015 Apr
TI  - Investigation of flexural strength and cytotoxicity of acrylic resin copolymers 
      by using different polymerization methods.
PG  - 98-107
LID - 10.4047/jap.2015.7.2.98 [doi]
AB  - PURPOSE: The aim of this study was to appraise the some mechanical properties of 
      polymethyl methacrylate based denture base resin polymerized by copolymerization 
      mechanism, and to investigate the cytotoxic effect of these copolymer resins. 
      MATERIALS AND METHODS: 2-hydroxyethyl methacrylate (HEMA) and isobutyl 
      methacrylate (IBMA) were added to monomers of conventional heat polymerized and 
      injection-molded poly methyl methacrylate (PMMA) resin contents of 2%, 3%, and 5% 
      by volume and polymerization was carried out. Three-point bending test was 
      performed to detect flexural strength and the elasticity modulus of the resins. 
      To determine the statistical differences between the study groups, the 
      Kruskall-Wallis test was performed. Then pairwise comparisons were performed 
      between significant groups by Mann-Whitney U test. Agar-overlay test was 
      performed to determine cytotoxic effect of copolymer resins. Chemical analysis 
      was determined by FTIR spectrum. RESULTS: Synthesis of the copolymer was approved 
      by FTIR spectroscopy. Within the conventional heat-polymerized group maximum 
      transverse strength had been seen in the HEMA 2% concentration; however, when the 
      concentration ratio increased, the strength decreased. In the injection-molded 
      group, maximum transverse strength had been seen in the IBMA 2% concentration; 
      also as the concentration ratio increased, the strength decreased. Only IBMA 
      showed no cytotoxic effect at low concentrations when both two polymerization 
      methods applied while HEMA showed cytotoxic effect in the injection-molded 
      resins. CONCLUSION: Within the limitations of this study, it may be concluded 
      that IBMA and HEMA may be used in low concentration and at high temperature to 
      obtain non-cytotoxic and durable copolymer structure.
FAU - Sahin, Onur
AU  - Sahin O
AUID- ORCID: 0000-0002-8018-6946
AD  - Department of Prosthodontics, Faculty of Dentistry, Bulent Ecevit University, 
      Zonguldak, Turkey.
FAU - Ozdemir, Ali Kemal
AU  - Ozdemir AK
AD  - Department of Prosthodontics, Faculty of Dentistry, Cumhuriyet University, Sivas, 
      Turkey.
FAU - Turgut, Mehmet
AU  - Turgut M
AD  - Department of Prosthodontics, Dentaforum Dental Clinic, Kayseri, Turkey.
FAU - Boztug, Ali
AU  - Boztug A
AD  - Department of Chemistry, Tunceli University, Tunceli, Turkey.
FAU - Sumer, Zeynep
AU  - Sumer Z
AD  - Department of Microbiology Faculty of Medical, Cumhuriyet University, Sivas, 
      Turkey.
LA  - eng
PT  - Journal Article
DEP - 20150423
PL  - Korea (South)
TA  - J Adv Prosthodont
JT  - The journal of advanced prosthodontics
JID - 101521064
PMC - PMC4414953
OTO - NOTNLM
OT  - 2-Hydroxyethyl methacrylate
OT  - Acrylic resin
OT  - Copolymer
OT  - Cytotoxicity
OT  - Flexural strength
OT  - Isobutyl methacrylate
EDAT- 2015/05/02 06:00
MHDA- 2015/05/02 06:01
PMCR- 2015/04/01
CRDT- 2015/05/02 06:00
PHST- 2014/05/23 00:00 [received]
PHST- 2014/11/24 00:00 [revised]
PHST- 2015/02/05 00:00 [accepted]
PHST- 2015/05/02 06:00 [entrez]
PHST- 2015/05/02 06:00 [pubmed]
PHST- 2015/05/02 06:01 [medline]
PHST- 2015/04/01 00:00 [pmc-release]
AID - 10.4047/jap.2015.7.2.98 [doi]
PST - ppublish
SO  - J Adv Prosthodont. 2015 Apr;7(2):98-107. doi: 10.4047/jap.2015.7.2.98. Epub 2015 
      Apr 23.