PMID- 2594051
OWN - NLM
STAT- MEDLINE
DCOM- 19900119
LR  - 20190908
IS  - 0301-486X (Print)
IS  - 0301-486X (Linking)
VI  - 108
IP  - 2
DP  - 1989 Nov
TI  - Polyclonal B cell activation in paracoccidioidomycosis. Polyclonal activation in 
      paracoccidioidomycosis.
PG  - 89-93
AB  - Paracoccidioidomycosis (PCM) is often associated with hypergammaglobulinemia and 
      increased serum levels of circulating immune complexes (CIC). In order to 
      investigate whether polyclonal B lymphocyte activation (PBA) is a current process 
      in PCM, we measured the numbers of IgG secreting cells (IgG SC) in the peripheral 
      blood of 16 patients and of 8 healthy controls. The numbers of IgG SC were found 
      to be significantly elevated in PCM patients. We also observed increased serum 
      levels of IgG, IgA and CIC. These data reflect an activation of B lymphocytes in 
      PCM patients.
FAU - Chequer-Bou-Habib, D
AU  - Chequer-Bou-Habib D
AD  - Departamento de Imunologia, WHO Collaborating Centre for Research and Training in 
      the Immunology of Parasitic Diseases, Rio de Janeiro, Brazil.
FAU - Daniel-Ribeiro, C
AU  - Daniel-Ribeiro C
FAU - Banic, D M
AU  - Banic DM
FAU - do Valle, A C
AU  - do Valle AC
FAU - Galvao-Castro, B
AU  - Galvao-Castro B
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Mycopathologia
JT  - Mycopathologia
JID - 7505689
RN  - 0 (Immunoglobulin G)
SB  - IM
MH  - B-Lymphocytes/*immunology
MH  - Humans
MH  - Immunoglobulin G/*immunology
MH  - *Lymphocyte Activation
MH  - Paracoccidioidomycosis/*immunology
EDAT- 1989/11/01 00:00
MHDA- 1989/11/01 00:01
CRDT- 1989/11/01 00:00
PHST- 1989/11/01 00:00 [pubmed]
PHST- 1989/11/01 00:01 [medline]
PHST- 1989/11/01 00:00 [entrez]
AID - 10.1007/BF00436058 [doi]
PST - ppublish
SO  - Mycopathologia. 1989 Nov;108(2):89-93. doi: 10.1007/BF00436058.