PMID- 25950453
OWN - NLM
STAT- MEDLINE
DCOM- 20160415
LR  - 20220410
IS  - 1530-0447 (Electronic)
IS  - 0031-3998 (Linking)
VI  - 78
IP  - 2
DP  - 2015 Aug
TI  - Efficacy and safety of acupuncture in children: an overview of systematic 
      reviews.
PG  - 112-9
LID - 10.1038/pr.2015.91 [doi]
AB  - In recent years, acupuncture has increasingly being integrated into pediatric 
      health care. It was used on ~150,000 children (0.2%). We aim to update the 
      evidence for the efficacy and safety of acupuncture for children and evaluate the 
      methodological qualities of these studies to improve future research in this 
      area. We included 24 systematic reviews, comprising 142 randomized controlled 
      trials (RCTs) with 12,787 participants. Only 25% (6/24) reviews were considered 
      to be high quality (10.00 +/- 0.63). High-quality systematic reviews and Cochrane 
      systematic reviews tend to yield neutral or negative results (P = 0.052, 0.009 
      respectively). The efficacy of acupuncture for five diseases (Cerebral Palsy 
      (CP), nocturnal enuresis, tic disorders, amblyopia, and pain reduction) is 
      promising. It was unclear for hypoxic ischemic encephalopathy, attention deficit 
      hyperactivity disorder, mumps, autism spectrum disorder (ASD), asthma, 
      nausea/vomiting, and myopia. Acupuncture is not effective for epilepsy. Only six 
      reviews reported adverse events (AEs) and no fatal side effects were reported. 
      The efficacy of acupuncture for some diseases is promising and there have been no 
      fatal side effects reported. Further high-quality studies are justified, with 
      five diseases in particular as research priorities.
FAU - Yang, Chunsong
AU  - Yang C
AD  - Department of Pharmacy, Evidence-based Pharmacy Center, West China Second 
      Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and 
      Children, Sichuan University, Chengdu, China.
FAU - Hao, Zilong
AU  - Hao Z
AD  - Department of Neurology, West China Hospital, Sichuan University, Chengdu, China.
FAU - Zhang, Ling-Li
AU  - Zhang LL
AD  - Department of Pharmacy, Evidence-based Pharmacy Center, West China Second 
      Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and 
      Children, Sichuan University, Chengdu, China.
FAU - Guo, Qin
AU  - Guo Q
AD  - Department of Pediatrics, West China Second Hospital, Key Laboratory of Birth 
      Defects and Related Diseases of Women and Children, Sichuan University, Chengdu, 
      China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20150507
PL  - United States
TA  - Pediatr Res
JT  - Pediatric research
JID - 0100714
SB  - IM
MH  - Acupuncture Therapy/*adverse effects/*standards
MH  - Child
MH  - Humans
MH  - Patient Safety
MH  - Randomized Controlled Trials as Topic
EDAT- 2015/05/08 06:00
MHDA- 2016/04/16 06:00
CRDT- 2015/05/08 06:00
PHST- 2014/09/23 00:00 [received]
PHST- 2015/01/26 00:00 [accepted]
PHST- 2015/05/08 06:00 [entrez]
PHST- 2015/05/08 06:00 [pubmed]
PHST- 2016/04/16 06:00 [medline]
AID - pr201591 [pii]
AID - 10.1038/pr.2015.91 [doi]
PST - ppublish
SO  - Pediatr Res. 2015 Aug;78(2):112-9. doi: 10.1038/pr.2015.91. Epub 2015 May 7.