PMID- 25955822
OWN - NLM
STAT- MEDLINE
DCOM- 20161011
LR  - 20161230
IS  - 1464-5165 (Electronic)
IS  - 0963-8288 (Linking)
VI  - 38
IP  - 5
DP  - 2016
TI  - Responsiveness of selected outcome measures of participation restriction and 
      quality of life in patients with multiple sclerosis.
PG  - 482-6
LID - 10.3109/09638288.2015.1044622 [doi]
AB  - PURPOSE: To evaluate the responsiveness of two outcome measures of participation 
      restriction [as measured by the Community Integration Questionnaire (CIQ)] and 
      quality of life [as measured by the Multiple Sclerosis Quality of Life (MSQOL)] 
      following a physiotherapy intervention in patients with multiple sclerosis (MS). 
      METHOD: A sample of 265 patients completed both instruments first at the time of 
      initial visit and then after 4-6 weeks physiotherapy. In addition, patients were 
      asked to complete the 7-point global rating scale as an external criterion of 
      change at the post-intervention time. The responsiveness was evaluated using the 
      receiver operating characteristics (ROC) method and the correlation analysis. Two 
      useful statistics were area under the ROC curve (AUC) and the minimally 
      clinically important difference (MCID). The AUC and correlation coefficient 
      greater than 0.70 were considered as acceptable responsiveness. RESULTS: The CIQ 
      achieved the acceptable responsiveness with an AUC of 0.81. However, the AUCs of 
      0.61 and 0.66 were obtained for the MSQOL physical and mental, respectively. 
      Moreover, good correlation coefficient was obtained for the CIQ (Gamma = 0.76) 
      while fair correlations of 0.28 and 0.33 were obtained for the MSQOL physical and 
      mental, respectively. The MCIDs were approximately 0.50, 1.5 and 2.5 points for 
      the CIQ, MSQOL physical and mental, respectively. CONCLUSIONS: In contrast to the 
      MSQOL, the CIQ was responsive outcome measure in detecting changes in 
      participation restriction of patients with MS. Moreover, the MCID values obtained 
      in this study will help the clinicians and researchers to determine if a patient 
      with MS has experienced a true change following physiotherapy intervention. 
      IMPLICATIONS FOR REHABILITATION: The results provide valuable information 
      regarding to the ability of two outcome measures (i.e. the CIQ and MSQOL) to 
      detect treatment effects in patients with MS. In contrast to the MSQOL, the CIQ 
      is a responsive measure to changes in participation restriction due to 
      physiotherapy. A patient with MS had to change at least 0.50 point on the CIQ, 
      1.5 points on the MSQOL physical and 2.5 points on the MSQOL mental to be judged 
      as having clinically changed.
FAU - Taheri, Mahdie
AU  - Taheri M
AD  - a Musculoskeletal Rehabilitation Research Center, Ahvaz Jundishapur University of 
      Medical Sciences , Ahvaz , Iran .
FAU - Negahban, Hossein
AU  - Negahban H
AD  - b Department of Physical Therapy, School of Paramedical Sciences , Mashhad 
      University of Medical Sciences , Mashhad , Iran , and.
FAU - Mostafaee, Neda
AU  - Mostafaee N
AD  - a Musculoskeletal Rehabilitation Research Center, Ahvaz Jundishapur University of 
      Medical Sciences , Ahvaz , Iran .
FAU - Salehi, Reza
AU  - Salehi R
AD  - a Musculoskeletal Rehabilitation Research Center, Ahvaz Jundishapur University of 
      Medical Sciences , Ahvaz , Iran .
FAU - Tabesh, Hamed
AU  - Tabesh H
AD  - c Department of Biostatistics and Epidemiology, School of Health , Ahvaz 
      Jundishapur University of Medical Sciences , Ahvaz , Iran.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20150508
PL  - England
TA  - Disabil Rehabil
JT  - Disability and rehabilitation
JID - 9207179
SB  - IM
MH  - Adult
MH  - Area Under Curve
MH  - *Community Integration
MH  - Disability Evaluation
MH  - Female
MH  - Humans
MH  - Iran
MH  - Male
MH  - Multiple Sclerosis/*rehabilitation
MH  - *Patient Participation
MH  - Physical Therapy Modalities/*standards
MH  - Quality of Life/*psychology
MH  - ROC Curve
MH  - Surveys and Questionnaires
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Community integration
OT  - multiple sclerosis
OT  - participation
OT  - quality of life
OT  - responsiveness
EDAT- 2015/05/09 06:00
MHDA- 2016/10/12 06:00
CRDT- 2015/05/09 06:00
PHST- 2015/05/09 06:00 [entrez]
PHST- 2015/05/09 06:00 [pubmed]
PHST- 2016/10/12 06:00 [medline]
AID - 10.3109/09638288.2015.1044622 [doi]
PST - ppublish
SO  - Disabil Rehabil. 2016;38(5):482-6. doi: 10.3109/09638288.2015.1044622. Epub 2015 
      May 8.