PMID- 25957201
OWN - NLM
STAT- MEDLINE
DCOM- 20151016
LR  - 20150509
IS  - 1881-6096 (Print)
IS  - 1881-6096 (Linking)
VI  - 67
IP  - 5
DP  - 2015 May
TI  - [Nonconvulsive status epilepticus; progress in clinical practice and research].
PG  - 553-62
LID - 10.11477/mf.1416200180 [doi]
AB  - Mainly after 2000, we have reported novel manifestations of nonconvulsive status 
      epilepticus (NCSE), such as reversible protracted coma, posthyperventilation 
      apnea, and higher brain dysfunctions, including Kluver-Bucy syndrome. In this 
      review, we discuss the progress in clinical practice and research of NCSE with 
      best available evidence, especially the spectrum of electroencephalographic 
      abnormalities in NCSE, clinical manifestations of malignant NCSE, relationship 
      between sudden unexpected death in epilepsy (SUDEP) and NCSE, and a strategy for 
      real-time neuromonitoring. In addition, we propose some new concepts, NCSE, such 
      as the antiepileptic drug-responsive neurological deficit (ADND), critical NCSE, 
      fosphenytoin challenge test, epilepsy-related organ dysfunction (Epi-ROD), and a 
      Neurocritical Score (Integrated Scale) for the comprehensive and serial 
      evaluation of neurocritical conditions. We emphasize the need for the 
      neuromonitoring of NCSE of broader neurological and neurocritical manifestations 
      not only in the intensive care unit but also in the emergency room, outpatient 
      clinic, inpatient ward, and social settings.
FAU - Nagayama, Masao
AU  - Nagayama M
AD  - Department of Neurology and Center for Stroke and Neurocritical Care, 
      International University of Health and Welfare Atami Hospital.
FAU - Yang, Sunghoon
AU  - Yang S
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Brain Nerve
JT  - Brain and nerve = Shinkei kenkyu no shinpo
JID - 101299709
RN  - 0 (Anticonvulsants)
SB  - IM
MH  - Anticonvulsants/therapeutic use
MH  - Death, Sudden
MH  - Humans
MH  - Patient Care Team
MH  - Practice Guidelines as Topic
MH  - *Status Epilepticus/complications/drug therapy
EDAT- 2015/05/10 06:00
MHDA- 2015/10/17 06:00
CRDT- 2015/05/10 06:00
PHST- 2015/05/10 06:00 [entrez]
PHST- 2015/05/10 06:00 [pubmed]
PHST- 2015/10/17 06:00 [medline]
AID - 1416200180 [pii]
AID - 10.11477/mf.1416200180 [doi]
PST - ppublish
SO  - Brain Nerve. 2015 May;67(5):553-62. doi: 10.11477/mf.1416200180.