PMID- 25959909
OWN - NLM
STAT- MEDLINE
DCOM- 20160204
LR  - 20221207
IS  - 1735-3947 (Electronic)
IS  - 1029-2977 (Linking)
VI  - 18
IP  - 5
DP  - 2015 May
TI  - Relationship between Anemia and Chronic Complications in Chinese Patients with 
      Type 2 Diabetes Mellitus.
PG  - 277-83
AB  - AIMS: To evaluate the potential association of anemia with micro- and 
      macrovascular complications in Chinese patient with type 2 diabetes mellitus 
      (T2DM). METHODS: A total of 1997 patients with T2DM were included in this 
      cross-sectional study. Patients were defined as anemic, if hemoglobin (Hb) levels 
      were < 13 g/dL in males and < 12 g/dL in females. Data on demographics, 
      anthropometric parameters, and co-morbidities were extracted for each patient. 
      RESULTS: Twenty two percent of T2DM patients (439/1997) had anemia, and those 
      patients with higher rates of micro- and macrovascular complications had higher 
      rates of anemia. Univariate logistic regression analysis showed that anemia was a 
      risk factor of microvascular complications (OR = 1.83, 95% CI: 1.45 - 2.31; P < 
      0.001) and macrovascular complications (OR = 2.10, 95% CI: 1.63 - 2.71; P < 
      0.001). After adjusting for conventional risk factors, anemia remained positively 
      associated with microvascular complications (OR = 1.52, 95% CI: 1.17 - 1.99), but 
      lost its association with macrovascular complications (OR = 1.01, 95% CI: 0.73 - 
      1.41). Anemia was also independently associated with diabetic retinopathy, 
      nephropathy, and peripheral neuropathy. CONCLUSIONS: These findings suggest that 
      anemia was related to both micro- and macrovascular complications in Chinese 
      patients with T2DM, but was only an independent risk factor of microvascular 
      complications. Assessment of Hb levels in T2DM patients may help to prevent 
      subsequent diabetic micro- and macrovascular complications.
FAU - He, Bin Bin
AU  - He BB
AD  - Department of Endocrinology and Metabolism, Shanghai Clinical Center of Diabetes, 
      Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 
      Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, 
      China. weili63@hotmail. com, liwei1109078@163.com.
FAU - Xu, Miao
AU  - Xu M
AD  - Department of Endocrinology and Metabolism, Shanghai Clinical Center of Diabetes, 
      Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 
      Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, 
      China.
FAU - Wei, Li
AU  - Wei L
AD  - Department of Endocrinology and Metabolism, Shanghai Clinical Center of Diabetes, 
      Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 
      Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, 
      China.
FAU - Gu, Yun Juan
AU  - Gu YJ
AD  - Department of Endocrinology and Metabolism, Shanghai Clinical Center of Diabetes, 
      Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 
      Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, 
      China.
FAU - Han, Jun Feng
AU  - Han JF
AD  - Department of Endocrinology and Metabolism, Shanghai Clinical Center of Diabetes, 
      Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 
      Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, 
      China.
FAU - Liu, Yu Xiang
AU  - Liu YX
AD  - Department of Endocrinology and Metabolism, Shanghai Clinical Center of Diabetes, 
      Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 
      Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, 
      China.
FAU - Bao, Yu Qian
AU  - Bao YQ
AD  - Department of Endocrinology and Metabolism, Shanghai Clinical Center of Diabetes, 
      Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 
      Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, 
      China.
FAU - Jia, Wei Ping
AU  - Jia WP
AD  - Department of Endocrinology and Metabolism, Shanghai Clinical Center of Diabetes, 
      Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 
      Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, 
      China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Iran
TA  - Arch Iran Med
JT  - Archives of Iranian medicine
JID - 100889644
SB  - IM
MH  - Adult
MH  - Aged
MH  - Anemia/*complications
MH  - Asian People
MH  - China
MH  - Chronic Disease
MH  - Comorbidity
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/*complications
MH  - Diabetic Retinopathy
MH  - Female
MH  - Humans
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
MH  - Vascular Diseases/*complications
EDAT- 2015/05/12 06:00
MHDA- 2016/02/05 06:00
CRDT- 2015/05/12 06:00
PHST- 2015/05/12 06:00 [entrez]
PHST- 2015/05/12 06:00 [pubmed]
PHST- 2016/02/05 06:00 [medline]
AID - 005 [pii]
PST - ppublish
SO  - Arch Iran Med. 2015 May;18(5):277-83.