PMID- 25960703
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220317
IS  - 1609-0985 (Print)
IS  - 2199-4757 (Electronic)
IS  - 1609-0985 (Linking)
VI  - 35
IP  - 2
DP  - 2015
TI  - Anti-fouling Coatings of Poly(dimethylsiloxane) Devices for Biological and 
      Biomedical Applications.
PG  - 143-155
AB  - Fouling initiated by nonspecific protein adsorption is a great challenge in 
      biomedical applications, including biosensors, bioanalytical devices, and 
      implants. Poly(dimethylsiloxane) (PDMS), a popular material with many attractive 
      properties for device fabrication in the biomedical field, suffers serious 
      fouling problems from protein adsorption due to its hydrophobic nature, which 
      limits the practical use of PDMS-based devices. Effort has been made to develop 
      biocompatible materials for anti-fouling coatings of PDMS. In this review, 
      typical nonfouling materials for PDMS coatings are introduced and the associated 
      basic anti-fouling mechanisms, including the steric repulsion mechanism and the 
      hydration layer mechanism, are described. Understanding the relationships between 
      the characteristics of coating materials and the accompanying anti-fouling 
      mechanisms is critical for preparing PDMS coatings with desirable anti-fouling 
      properties.
FAU - Zhang, Hongbin
AU  - Zhang H
AD  - Department of Mechanical Engineering, University of British Columbia, Vancouver, 
      Canada.
FAU - Chiao, Mu
AU  - Chiao M
AD  - Department of Mechanical Engineering, University of British Columbia, Vancouver, 
      Canada.
LA  - eng
PT  - Journal Article
DEP - 20150401
PL  - China
TA  - J Med Biol Eng
JT  - Journal of medical and biological engineering
JID - 101123071
PMC - PMC4414934
OTO - NOTNLM
OT  - Anti-fouling
OT  - Biomedical devices
OT  - Poly(dimethylsiloxane) (PDMS)
OT  - Surface modification
EDAT- 2015/05/12 06:00
MHDA- 2015/05/12 06:01
PMCR- 2015/04/01
CRDT- 2015/05/12 06:00
PHST- 2013/11/29 00:00 [received]
PHST- 2014/01/13 00:00 [accepted]
PHST- 2015/05/12 06:00 [entrez]
PHST- 2015/05/12 06:00 [pubmed]
PHST- 2015/05/12 06:01 [medline]
PHST- 2015/04/01 00:00 [pmc-release]
AID - 29 [pii]
AID - 10.1007/s40846-015-0029-4 [doi]
PST - ppublish
SO  - J Med Biol Eng. 2015;35(2):143-155. doi: 10.1007/s40846-015-0029-4. Epub 2015 Apr 
      1.