PMID- 25960854 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20150511 LR - 20240326 IS - 2035-3006 (Print) IS - 2035-3006 (Electronic) IS - 2035-3006 (Linking) VI - 7 IP - 1 DP - 2015 TI - A case of rupioid syphilis masquerading as aggressive cutaneous lymphoma. PG - e2015026 LID - 10.4084/MJHID.2015.026 [doi] LID - e2015026 AB - Secondary syphilis has been known since the late 19th century as the great imitator; however, some experts now regard cutaneous lymphoma as the great imitator of skin disease. Either disease, at times an equally fastidious diagnosis, has reported to mimic each other even. It is thus vital to consider these possibilities when presented with a patient demonstrating peculiar skin lesions. No other manifestation of secondary syphilis may pose such quandary as a rare case of rupioid syphilis impersonating cutaneous lymphoma. We present such a case, of a 36-year-old HIV positive male, misdiagnosed with aggressive cutaneous lymphoma, actually exhibiting rupioid syphilis thought secondary to immune reconstitution inflammatory syndrome (IRIS). FAU - Braue, Jonathan AU - Braue J AD - University of South Florida Morsani College of Medicine, 12901 Bruce B. Down Blvd, Tampa, Florida 33612-4742. FAU - Hagele, Thomas AU - Hagele T AD - University of South Florida Morsani College of Medicine, Department of Dermatology and Cutaneous Surgery, 12901 Bruce B. Down Blvd, Tampa, Florida 33612-4742. FAU - Yacoub, Abraham Tareq AU - Yacoub AT AD - Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, Florida 33612-9497. FAU - Mannivanan, Suganya AU - Mannivanan S AD - University of South Florida, Morsani College of Medicine, Division of Infectious Disease and International Medicine, 1 Tampa General Circle, G323, Tampa, Florida 33612-9497. FAU - Sokol, Lubomir AU - Sokol L AD - Moffitt Cancer Center, Department of Cutaneous Oncology, 12902 Magnolia Drive, Tampa, Florida 33612-9497. FAU - Glass, Frank AU - Glass F AD - Moffitt Cancer Center, Department of Cutaneous Oncology, 12902 Magnolia Drive, Tampa, Florida 33612-9497. FAU - Greene, John N AU - Greene JN AD - Moffitt Cancer Center, University of South Florida College of Medicine, 12902 Magnolia Drive, Tampa, Florida 33612-9497. LA - eng PT - Case Reports DEP - 20150420 PL - Italy TA - Mediterr J Hematol Infect Dis JT - Mediterranean journal of hematology and infectious diseases JID - 101530512 PMC - PMC4418386 EDAT- 2015/05/12 06:00 MHDA- 2015/05/12 06:01 PMCR- 2015/01/01 CRDT- 2015/05/12 06:00 PHST- 2014/12/19 00:00 [received] PHST- 2015/03/03 00:00 [accepted] PHST- 2015/05/12 06:00 [entrez] PHST- 2015/05/12 06:00 [pubmed] PHST- 2015/05/12 06:01 [medline] PHST- 2015/01/01 00:00 [pmc-release] AID - mjhid-7-1-e2015026 [pii] AID - 10.4084/MJHID.2015.026 [doi] PST - epublish SO - Mediterr J Hematol Infect Dis. 2015 Apr 20;7(1):e2015026. doi: 10.4084/MJHID.2015.026. eCollection 2015.