PMID- 25961042
OWN - NLM
STAT- MEDLINE
DCOM- 20160204
LR  - 20181113
IS  - 2314-6141 (Electronic)
IS  - 2314-6133 (Print)
VI  - 2015
DP  - 2015
TI  - A Novel Operative Procedure for Pelvic Organ Prolapse Utilizing a MRI-Visible 
      Mesh Implant: Safety and Outcome of Modified Laparoscopic Bilateral Sacropexy.
PG  - 860784
LID - 10.1155/2015/860784 [doi]
LID - 860784
AB  - INTRODUCTION: Sacropexy is a generally applied treatment of prolapse, yet there 
      are known possible complications of it. An essential need exists for better 
      alloplastic materials. METHODS: Between April 2013 and June 2014, we performed a 
      modified laparoscopic bilateral sacropexy (MLBS) in 10 patients using a 
      MRI-visible PVDF mesh implant. Selected patients had prolapse POP-Q stages II-III 
      and concomitant OAB. We studied surgery-related morbidity, anatomical and 
      functional outcome, and mesh-visibility in MRI. Mean follow-up was 7.4 months. 
      RESULTS: Concomitant colporrhaphy was conducted in 1/10 patients. Anatomical 
      success was defined as POP-Q stage 0-I. Apical success rate was 100% and remained 
      stable. A recurrent cystocele was seen in 1/10 patients during follow-up without 
      need for intervention. Out of 6 (6/10) patients with preoperative SUI, 5/6 were 
      healed and 1/6 persisted. De-novo SUI was seen in 1/10 patients. Complications 
      requiring a relaparoscopy were seen in 2/10 patients. 8/10 patients with OAB were 
      relieved postoperatively. The first in-human magnetic resonance visualization of 
      a prolapse mesh implant was performed and showed good quality of visualization. 
      CONCLUSION: MLBS is a feasible and safe procedure with favorable anatomical and 
      functional outcome and good concomitant healing rates of SUI and OAB. Prospective 
      data and larger samples are required.
FAU - Joukhadar, Ralf
AU  - Joukhadar R
AUID- ORCID: 0000-0002-0127-480X
AD  - Department of Obstetrics and Gynecology, University Hospital Homburg, Kirrberger 
      Strasse 100, 66424 Homburg, Germany.
FAU - Meyberg-Solomayer, Gabriele
AU  - Meyberg-Solomayer G
AD  - Department of Obstetrics and Gynecology, University Hospital Homburg, Kirrberger 
      Strasse 100, 66424 Homburg, Germany.
FAU - Hamza, Amr
AU  - Hamza A
AUID- ORCID: 0000-0003-3630-0593
AD  - Department of Obstetrics and Gynecology, University Hospital Homburg, Kirrberger 
      Strasse 100, 66424 Homburg, Germany.
FAU - Radosa, Julia
AU  - Radosa J
AD  - Department of Obstetrics and Gynecology, University Hospital Homburg, Kirrberger 
      Strasse 100, 66424 Homburg, Germany.
FAU - Bader, Werner
AU  - Bader W
AD  - Department of Obstetrics and Gynecology, Klinikum Bielefeld, Teutoburger Strasse 
      50, 33604 Bielefeld, Germany.
FAU - Barski, Dimitri
AU  - Barski D
AUID- ORCID: 0000-0001-8611-8250
AD  - Department of Urology, Lukaskrankenhaus GmbH, Preussenstrasse 84, 41464 Neuss, 
      Germany.
FAU - Ismaeel, Fakher
AU  - Ismaeel F
AUID- ORCID: 0000-0003-4653-9653
AD  - Department of Gynecology, University Hospital Charite, Campus Virchow-Klinikum 
      (CVK), Mittelallee 9, 13353 Berlin, Germany.
FAU - Schneider, Guenther
AU  - Schneider G
AD  - Department of Radiology, University Hospital Homburg, Kirrberger Strasse 100, 
      66424 Homburg, Germany.
FAU - Solomayer, Erich
AU  - Solomayer E
AD  - Department of Obstetrics and Gynecology, University Hospital Homburg, Kirrberger 
      Strasse 100, 66424 Homburg, Germany.
FAU - Baum, Sascha
AU  - Baum S
AUID- ORCID: 0000-0001-6057-6042
AD  - Department of Obstetrics and Gynecology, University Hospital Homburg, Kirrberger 
      Strasse 100, 66424 Homburg, Germany.
LA  - eng
PT  - Journal Article
DEP - 20150419
PL  - United States
TA  - Biomed Res Int
JT  - BioMed research international
JID - 101600173
SB  - IM
MH  - Aged
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Laparoscopy/*adverse effects/methods
MH  - Magnetic Resonance Imaging
MH  - Middle Aged
MH  - Pelvic Organ Prolapse/physiopathology/*surgery
MH  - Postoperative Complications/*physiopathology
MH  - Prospective Studies
MH  - Surgical Mesh/adverse effects
MH  - Treatment Outcome
PMC - PMC4417564
EDAT- 2015/05/12 06:00
MHDA- 2016/02/05 06:00
PMCR- 2015/04/19
CRDT- 2015/05/12 06:00
PHST- 2014/07/25 00:00 [received]
PHST- 2014/10/07 00:00 [accepted]
PHST- 2015/05/12 06:00 [entrez]
PHST- 2015/05/12 06:00 [pubmed]
PHST- 2016/02/05 06:00 [medline]
PHST- 2015/04/19 00:00 [pmc-release]
AID - 10.1155/2015/860784 [doi]
PST - ppublish
SO  - Biomed Res Int. 2015;2015:860784. doi: 10.1155/2015/860784. Epub 2015 Apr 19.