PMID- 25966070 OWN - NLM STAT- MEDLINE DCOM- 20160421 LR - 20221207 IS - 1676-5680 (Electronic) IS - 1676-5680 (Linking) VI - 14 IP - 2 DP - 2015 Apr 10 TI - Promotive effect of comprehensive management on achieving blood glucose control in senile type 2 diabetics. PG - 3062-70 LID - 10.4238/2015.April.10.16 [doi] AB - The aim of this study was to evaluate the control of blood glucose and glycosylated hemoglobin A1c (HbA1c) and its influencing factors, in elderly type 2 diabetic mellitus (T2DM) patients undergoing comprehensive management. After years of comprehensive prevention of and control measures for diabetes, elderly T2DM patients who were receiving long-term health care were comprehensively evaluated through an annual physical examination. In addition to routine health examination, the patients were required to undergo HbA1c measurement. Among 688 patients, 652 were men and 36 were women, with a mean age of 78.2 +/- 9.1 years. The average HbA1c was 6.6 +/- 0.9%. A total of 50.6% of the patients had HbA1c <6.5%, whereas 76.3% had HbA1c <7.0%. Among all patients, 77.1, 46.4, 66.1, 67.8, 36.3, and 57.4% achieved the target total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglyceride (TG), blood pressure, and body mass index (BMI) levels, respectively. The duration of disease and type of treatment, as well as the LDL, HDL, TG, BMI, and blood pressure levels, were significantly associated with HbA1c control. No patient was admitted because of ketoacidosis or hyperosmolar nonketotic diabetic coma in 10 years. Approximately half of the T2DM patients achieved the target HbA1c level. The more effective blood glucose control observed in our study compared with previous studies can be attributed to the effective monitoring of medical conditions and comprehensive management of patients. FAU - Yan, S-T AU - Yan ST AD - Department of Geriatric Endocrinology, PLA General Hospital, Beijing, China. FAU - Li, C-X AU - Li CX AD - Department of Geriatric Endocrinology, PLA General Hospital, Beijing, China. FAU - Li, C-L AU - Li CL AD - Department of Geriatric Endocrinology, PLA General Hospital, Beijing, China. FAU - Li, J AU - Li J AD - Department of Geriatric Endocrinology, PLA General Hospital, Beijing, China. FAU - Shao, Y-H AU - Shao YH AD - Department of Geriatric Endocrinology, PLA General Hospital, Beijing, China. FAU - Liu, Y AU - Liu Y AD - Department of Geriatric Endocrinology, PLA General Hospital, Beijing, China. FAU - Zhong, W-W AU - Zhong WW AD - Department of Geriatric Endocrinology, PLA General Hospital, Beijing, China. FAU - Fang, F-S AU - Fang FS AD - Department of Geriatric Endocrinology, PLA General Hospital, Beijing, China. FAU - Sun, B-R AU - Sun BR AD - Department of Geriatric Endocrinology, PLA General Hospital, Beijing, China. FAU - Tian, H AU - Tian H AD - Department of Geriatric Endocrinology, PLA General Hospital, Beijing, China stthcn@126.com. LA - eng PT - Journal Article DEP - 20150410 PL - Brazil TA - Genet Mol Res JT - Genetics and molecular research : GMR JID - 101169387 RN - 0 (Blood Glucose) RN - 0 (Glycated Hemoglobin A) RN - 0 (hemoglobin A1c protein, human) RN - 97C5T2UQ7J (Cholesterol) SB - IM MH - Aged MH - Aged, 80 and over MH - Alzheimer Disease/*blood/*therapy MH - Blood Glucose/*metabolism MH - Cholesterol/blood MH - Diabetes Mellitus, Type 2/*blood/psychology/*therapy MH - Female MH - Glycated Hemoglobin/metabolism MH - Humans MH - Male EDAT- 2015/05/13 06:00 MHDA- 2016/04/22 06:00 CRDT- 2015/05/13 06:00 PHST- 2015/05/13 06:00 [entrez] PHST- 2015/05/13 06:00 [pubmed] PHST- 2016/04/22 06:00 [medline] AID - gmr4696 [pii] AID - 10.4238/2015.April.10.16 [doi] PST - epublish SO - Genet Mol Res. 2015 Apr 10;14(2):3062-70. doi: 10.4238/2015.April.10.16.