PMID- 25966165
OWN - NLM
STAT- MEDLINE
DCOM- 20160208
LR  - 20161125
IS  - 1676-5680 (Electronic)
IS  - 1676-5680 (Linking)
VI  - 14
IP  - 2
DP  - 2015 Apr 27
TI  - High-resolution color doppler ultrasound examination and related risk factor 
      analysis of lower extremity vasculopathy in type 2 diabetes patients.
PG  - 3939-47
LID - 10.4238/2015.April.27.8 [doi]
AB  - This study aims to investigate the value of high-resolution color Doppler 
      ultrasonography (HR-CDU) in the evaluation of lower-extremity vasculopathy (LEV) 
      and its related risk factors in type 2 diabetes mellitus (T2DM) patients. Two 
      hundred forty T2DM patients were selected, who underwent lower-extremity arterial 
      HR-CDU. The patients were divided into the LEV group (V group) and the 
      nonvasculopathy group (A group). The V group was then divided into the mild (B 
      group), moderate (C group), and severe (D group) subgroups. The relevant clinical 
      parameters were simultaneously recorded. The results showed that the 
      lesion-positive detection rate of HR-CDU was significantly higher than that of 
      clinical examination. The age, disease duration, smoking history, blood pressure, 
      blood sugar, fibrinogen (FIB), C-reactive protein (CRP), uric acid (UA), and 
      urinary albumin excretion (UAE) in the V group were higher than in the N group. 
      In the logistic regression analysis, smoking history, age, disease duration, FIB, 
      UA, and fasting blood glucose were independent risk factors of T2DM LEV. The 
      incidence of LEV in T2DM patients increased significantly with increasing age, 
      UA, FIB, CRP, UAE, disease duration, and smoking history, and the vasculopathy 
      level became more severe. In conclusion, age, disease duration, smoking history, 
      blood pressure, blood sugar, FIB, CRP, UA, and UAE are the related risk factors 
      of LEV in T2DM patients.
FAU - Xu, J
AU  - Xu J
AD  - Second Division, Department of Endocrinology, Hebei Cangzhou Central Hospital, 
      Hebei, China jxgycn@163.com.
FAU - Wang, G
AU  - Wang G
AD  - Second Division, Department of Endocrinology, Hebei Cangzhou Central Hospital, 
      Hebei, China.
FAU - Fu, D
AU  - Fu D
AD  - Second Division, Department of Endocrinology, Hebei Cangzhou Central Hospital, 
      Hebei, China.
FAU - Su, N
AU  - Su N
AD  - Second Division, Department of Endocrinology, Hebei Cangzhou Central Hospital, 
      Hebei, China.
FAU - Wang, L
AU  - Wang L
AD  - Second Division, Department of Endocrinology, Hebei Cangzhou Central Hospital, 
      Hebei, China.
FAU - Gao, F
AU  - Gao F
AD  - Second Division, Department of Endocrinology, Hebei Cangzhou Central Hospital, 
      Hebei, China.
FAU - Guo, N
AU  - Guo N
AD  - Second Division, Department of Endocrinology, Hebei Cangzhou Central Hospital, 
      Hebei, China.
LA  - eng
PT  - Journal Article
DEP - 20150427
PL  - Brazil
TA  - Genet Mol Res
JT  - Genetics and molecular research : GMR
JID - 101169387
SB  - IM
MH  - Adult
MH  - Diabetes Mellitus, Type 2/*complications
MH  - Female
MH  - Humans
MH  - Leg/*blood supply
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
MH  - Ultrasonography, Doppler, Color
MH  - Vascular Diseases/complications/*diagnostic imaging
EDAT- 2015/05/13 06:00
MHDA- 2016/02/09 06:00
CRDT- 2015/05/13 06:00
PHST- 2015/05/13 06:00 [entrez]
PHST- 2015/05/13 06:00 [pubmed]
PHST- 2016/02/09 06:00 [medline]
AID - gmr4876 [pii]
AID - 10.4238/2015.April.27.8 [doi]
PST - epublish
SO  - Genet Mol Res. 2015 Apr 27;14(2):3939-47. doi: 10.4238/2015.April.27.8.