PMID- 25970090
OWN - NLM
STAT- MEDLINE
DCOM- 20160321
LR  - 20161125
IS  - 1931-8405 (Electronic)
IS  - 0889-2229 (Linking)
VI  - 31
IP  - 7
DP  - 2015 Jul
TI  - Change in the Prevalence of HIV-1 and the Rate of Transmitted Drug-Resistant 
      HIV-1 in Haiphong, Northern Vietnam.
PG  - 757-9
LID - 10.1089/AID.2015.0071 [doi]
AB  - We previously reported a significant decrease in HIV-1 prevalence, with no 
      increase in drug-resistant HIV-1 among injecting drug users (IDU), female sex 
      workers (FSW), and blood donors (BD), in Haiphong, Vietnam, from 2007 to 2009. In 
      2012, 388 IDU, 51 FSW, and 200 BD were recruited for further analysis. None had a 
      history of antiretroviral treatment. From 2007 to 2012, HIV-1 prevalence was 
      reduced from 35.9% to 18.6% (p<0.001), 23.1% to 9.8% (p<0.05), and 2.9% to 1% 
      (p=0.29) in IDU, FSW, and BD, respectively. Of 79 anti-HIV-1 antibody-positive 
      samples, 61 were successfully analyzed for the pol-reverse transcriptase (RT) 
      region. All HIV-1 strains were CRF01_AE. Nonnucleoside RT inhibitor-resistant 
      mutations, Y181C/I, were detected in three subjects; one had the nucleoside RT 
      inhibitor-resistant mutations L74V and M184V and one had E138K. The prevalence of 
      transmitted drug-resistant HIV-1 in Haiphong increased slightly from 1.8% in 2007 
      to 6.6% in 2012 (p=0.06).
FAU - Pham, Hung Viet
AU  - Pham HV
AD  - 1 Department of Viral Infection and International Health, Graduate School of 
      Medical Sciences, Kanazawa University , Kanazawa, Japan .
FAU - Ishizaki, Azumi
AU  - Ishizaki A
AD  - 1 Department of Viral Infection and International Health, Graduate School of 
      Medical Sciences, Kanazawa University , Kanazawa, Japan .
FAU - Nguyen, Cuong Hung
AU  - Nguyen CH
AD  - 1 Department of Viral Infection and International Health, Graduate School of 
      Medical Sciences, Kanazawa University , Kanazawa, Japan .
AD  - 2 Hai Phong Medical University , Hai Phong, Vietnam .
FAU - Saina, Matilda Chelimo
AU  - Saina MC
AD  - 1 Department of Viral Infection and International Health, Graduate School of 
      Medical Sciences, Kanazawa University , Kanazawa, Japan .
FAU - Hoang, Huyen Thi Thanh
AU  - Hoang HT
AD  - 2 Hai Phong Medical University , Hai Phong, Vietnam .
FAU - Tran, Vuong Thi
AU  - Tran VT
AD  - 1 Department of Viral Infection and International Health, Graduate School of 
      Medical Sciences, Kanazawa University , Kanazawa, Japan .
AD  - 2 Hai Phong Medical University , Hai Phong, Vietnam .
FAU - Bi, Xiuqiong
AU  - Bi X
AD  - 1 Department of Viral Infection and International Health, Graduate School of 
      Medical Sciences, Kanazawa University , Kanazawa, Japan .
FAU - Pham, Thuc Van
AU  - Pham TV
AD  - 2 Hai Phong Medical University , Hai Phong, Vietnam .
FAU - Ichimura, Hiroshi
AU  - Ichimura H
AD  - 1 Department of Viral Infection and International Health, Graduate School of 
      Medical Sciences, Kanazawa University , Kanazawa, Japan .
LA  - eng
SI  - GENBANK/KF453803
SI  - GENBANK/KF453804
SI  - GENBANK/KF453805
SI  - GENBANK/KF453806
SI  - GENBANK/KF453807
SI  - GENBANK/KF453808
SI  - GENBANK/KF453809
SI  - GENBANK/KF453810
SI  - GENBANK/KF453811
SI  - GENBANK/KF453812
SI  - GENBANK/KF453813
SI  - GENBANK/KF453814
SI  - GENBANK/KF453815
SI  - GENBANK/KF453816
SI  - GENBANK/KF453817
SI  - GENBANK/KF453818
SI  - GENBANK/KF453819
SI  - GENBANK/KF453820
SI  - GENBANK/KF453821
SI  - GENBANK/KF453822
SI  - GENBANK/KF453823
SI  - GENBANK/KF453824
SI  - GENBANK/KF453825
SI  - GENBANK/KF453826
SI  - GENBANK/KF453827
SI  - GENBANK/KF453828
SI  - GENBANK/KF453829
SI  - GENBANK/KF453830
SI  - GENBANK/KF453831
SI  - GENBANK/KF453832
SI  - GENBANK/KF453833
SI  - GENBANK/KF453834
SI  - GENBANK/KF453835
SI  - GENBANK/KF453836
SI  - GENBANK/KF453837
SI  - GENBANK/KF453838
SI  - GENBANK/KF453839
SI  - GENBANK/KF453840
SI  - GENBANK/KF453841
SI  - GENBANK/KF453842
SI  - GENBANK/KF453843
SI  - GENBANK/KF453844
SI  - GENBANK/KF453845
SI  - GENBANK/KF453846
SI  - GENBANK/KF453847
SI  - GENBANK/KF453848
SI  - GENBANK/KF453849
SI  - GENBANK/KF453850
SI  - GENBANK/KF453851
SI  - GENBANK/KF453852
SI  - GENBANK/KF453853
SI  - GENBANK/KF453854
SI  - GENBANK/KF453855
SI  - GENBANK/KF453856
SI  - GENBANK/KF453857
SI  - GENBANK/KF453858
SI  - GENBANK/KF453859
SI  - GENBANK/KF453860
SI  - GENBANK/KF453861
SI  - GENBANK/KF453862
SI  - GENBANK/KF453863
PT  - Journal Article
DEP - 20150615
PL  - United States
TA  - AIDS Res Hum Retroviruses
JT  - AIDS research and human retroviruses
JID - 8709376
RN  - EC 2.7.7.- (reverse transcriptase, Human immunodeficiency virus 1)
RN  - EC 2.7.7.49 (HIV Reverse Transcriptase)
SB  - IM
MH  - Adult
MH  - Blood Donors
MH  - Disease Transmission, Infectious
MH  - *Drug Resistance, Viral
MH  - Female
MH  - Genetic Variation
MH  - *Genotype
MH  - HIV Infections/*epidemiology/transmission/*virology
MH  - HIV Reverse Transcriptase/genetics
MH  - HIV-1/*classification/*genetics/isolation & purification
MH  - Humans
MH  - Male
MH  - *Molecular Epidemiology
MH  - Molecular Sequence Data
MH  - Mutation, Missense
MH  - Prevalence
MH  - Sequence Analysis, DNA
MH  - Sex Work
MH  - Substance Abuse, Intravenous
MH  - Vietnam/epidemiology
EDAT- 2015/05/15 06:00
MHDA- 2016/03/22 06:00
CRDT- 2015/05/14 06:00
PHST- 2015/05/14 06:00 [entrez]
PHST- 2015/05/15 06:00 [pubmed]
PHST- 2016/03/22 06:00 [medline]
AID - 10.1089/AID.2015.0071 [doi]
PST - ppublish
SO  - AIDS Res Hum Retroviruses. 2015 Jul;31(7):757-9. doi: 10.1089/AID.2015.0071. Epub 
      2015 Jun 15.