PMID- 25971877
OWN - NLM
STAT- MEDLINE
DCOM- 20160113
LR  - 20220330
IS  - 1574-4647 (Electronic)
IS  - 0161-9152 (Print)
IS  - 0161-9152 (Linking)
VI  - 37
IP  - 3
DP  - 2015 Jun
TI  - Understanding the individual responsiveness to resistance training periodization.
PG  - 9793
LID - 10.1007/s11357-015-9793-x [doi]
LID - 55
AB  - This study was designed to compare the effects of linear periodization (LP) and 
      undulating periodization (UP) on functional capacity, neuromuscular function, 
      body composition, and cytokines in elderly sedentary women. We also aimed to 
      identify the presence of high responders (HR), medium responders (MR), and low 
      responders (LR) for irisin, interleukin-1 beta (IL-1beta), toll-like receptor-4 
      (TLR-4), and brain-derived neurotrophic factor (BDNF) to resistance training 
      (RT). Forty-nine elderly women were assigned to a control group, LP, and UP 
      scheme. Functional capacity, body composition, maximal strength, irisin, TLR-4, 
      BDNF, and IL-1beta were evaluated. Both periodization models were effective in 
      improving 45 degrees  leg press 1RM, chair-stand, arm curl, and time-up and go tests, 
      with no significant differences in body composition and cytokines. Furthermore, 
      HR, MR, and LR were identified for irisin, IL-1beta, TLR-4, and BDNF, with 
      differences between groups and moments. This study provides evidence that both 
      periodization models were effective in improving functional capacity and 
      neuromuscular function, with no effect on body composition and cytokines 
      (probably as a consequence of the different responsiveness). Furthermore, for the 
      first time, HR, MR, and LR were identified for irisin, IL1-beta, TLR-4, and BDNF in 
      response to RT.
FAU - Prestes, Jonato
AU  - Prestes J
AD  - Graduation Program on Physical Education, Catholic University of Brasilia (UCB), 
      Brasilia, Distrito Federal, Brazil, jonatop@gmail.com.
FAU - da Cunha Nascimento, Dahan
AU  - da Cunha Nascimento D
FAU - Tibana, Ramires Alsamir
AU  - Tibana RA
FAU - Teixeira, Tatiane Gomes
AU  - Teixeira TG
FAU - Vieira, Denis Cesar Leite
AU  - Vieira DC
FAU - Tajra, Vitor
AU  - Tajra V
FAU - de Farias, Darlan Lopes
AU  - de Farias DL
FAU - Silva, Alessandro Oliveira
AU  - Silva AO
FAU - Funghetto, Silvana Schwerz
AU  - Funghetto SS
FAU - de Souza, Vinicius Carolino
AU  - de Souza VC
FAU - Navalta, James Wilfred
AU  - Navalta JW
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150514
PL  - Netherlands
TA  - Age (Dordr)
JT  - Age (Dordrecht, Netherlands)
JID - 101250497
RN  - 0 (Biomarkers)
RN  - 0 (Brain-Derived Neurotrophic Factor)
RN  - 0 (FNDC5 protein, human)
RN  - 0 (Fibronectins)
RN  - 0 (Interleukin-1beta)
RN  - 0 (Toll-Like Receptor 4)
RN  - 7171WSG8A2 (BDNF protein, human)
SB  - IM
MH  - Aged
MH  - Biomarkers/*blood
MH  - Body Composition/physiology
MH  - Brain-Derived Neurotrophic Factor/blood
MH  - Female
MH  - Fibronectins/blood
MH  - Humans
MH  - Interleukin-1beta/blood
MH  - Muscle Strength/physiology
MH  - *Physical Fitness
MH  - Resistance Training/*methods
MH  - Sedentary Behavior
MH  - Toll-Like Receptor 4/blood
PMC - PMC4430497
EDAT- 2015/05/15 06:00
MHDA- 2016/01/14 06:00
PMCR- 2016/06/01
CRDT- 2015/05/15 06:00
PHST- 2015/02/08 00:00 [received]
PHST- 2015/05/04 00:00 [accepted]
PHST- 2015/05/15 06:00 [entrez]
PHST- 2015/05/15 06:00 [pubmed]
PHST- 2016/01/14 06:00 [medline]
PHST- 2016/06/01 00:00 [pmc-release]
AID - 9793 [pii]
AID - 10.1007/s11357-015-9793-x [doi]
PST - ppublish
SO  - Age (Dordr). 2015 Jun;37(3):9793. doi: 10.1007/s11357-015-9793-x. Epub 2015 May 
      14.