PMID- 25973877
OWN - NLM
STAT- MEDLINE
DCOM- 20161213
LR  - 20161230
IS  - 1939-2869 (Electronic)
IS  - 0891-1150 (Linking)
VI  - 82
IP  - 5
DP  - 2015 May
TI  - Penicillin allergy: A practical guide for clinicians.
PG  - 295-300
LID - 10.3949/ccjm.82a.14111 [doi]
AB  - Penicillin allergy is the most commonly reported drug allergy in the United 
      States. However, after undergoing a complete evaluation by a board-certified 
      allergist, including skin testing, 90% of patients labeled as 
      'penicillin-allergic' are able to tolerate penicillin. Clinical presentation is 
      key in classifying reactions as either mediated by or not mediated by 
      immunoglobulin E (IgE), and in determining which patients may benefit from 
      penicillin skin testing, graded-dose challenge, or desensitization. 
      Cross-reactivity between penicillin and other beta-lactams is less common than 
      previously thought.
CI  - Copyright (c) 2015 Cleveland Clinic.
FAU - Gonzalez-Estrada, Alexei
AU  - Gonzalez-Estrada A
AD  - Department of Allergy and Clinical Immunology, Respiratory Institute, Cleveland 
      Clinic, Cleveland, OH, USA. E-mail: gonzala5@ccf.org.
FAU - Radojicic, Cristine
AU  - Radojicic C
AD  - Department of Allergy and Clinical Immunology, Respiratory Institute, Cleveland 
      Clinic, USA.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Cleve Clin J Med
JT  - Cleveland Clinic journal of medicine
JID - 8703441
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Penicillins)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Anti-Bacterial Agents/*adverse effects
MH  - Cross Reactions/immunology
MH  - Drug Hypersensitivity/*diagnosis/etiology/immunology
MH  - Humans
MH  - Immunoglobulin E/immunology
MH  - Medical History Taking
MH  - Penicillins/*adverse effects
MH  - Practice Guidelines as Topic
MH  - Self Report
MH  - Skin Tests
EDAT- 2015/05/15 06:00
MHDA- 2016/12/15 06:00
CRDT- 2015/05/15 06:00
PHST- 2015/05/15 06:00 [entrez]
PHST- 2015/05/15 06:00 [pubmed]
PHST- 2016/12/15 06:00 [medline]
AID - 10.3949/ccjm.82a.14111 [doi]
PST - ppublish
SO  - Cleve Clin J Med. 2015 May;82(5):295-300. doi: 10.3949/ccjm.82a.14111.