PMID- 25978590 OWN - NLM STAT- MEDLINE DCOM- 20150728 LR - 20150518 IS - 1532-3145 (Electronic) IS - 0363-8715 (Linking) VI - 39 IP - 3 DP - 2015 May-Jun TI - Feasibility of 3-dimensional sampling perfection with application optimized contrast sequence in the evaluation of patients with hydrocephalus. PG - 321-8 LID - 10.1097/RCT.0000000000000206 [doi] AB - PURPOSE: This study aimed to investigate the effectiveness and additive value of T2W 3-dimensional sampling perfection with application optimized contrast (3D-SPACE) with variant flip-angle mode in imaging of all types of hydrocephalus. Our secondary objective was to assess the reliability of 3D-SPACE sequence and correspondence of the results with phase-contrast magnetic resonance imaging (PC-MRI)-based data. MATERIALS AND METHODS: Forty-one patients with hydrocephalus have undergone 3-T MRI. T2W 3D-SPACE sequence has been obtained in addition to routine hydrocephalus protocol. Cerebrospinal fluid circulation, presence/type/etiology of hydrocephalus, obstruction level scores, and diagnostic levels of confidence were evaluated separately by 2 radiologists. In the first session, routine sequences with PC-MRI were evaluated, and in another session, only 3D-SPACE and 3-dimensional magnetization prepared rapid acquisition gradient echo sequences were evaluated. Results obtained in these sessions were compared with each other and those obtained in consensus session. RESULTS: Agreement values were very good for both 3D-SPACE and PC-MRI sequences (P < 0.001 for all). Also, the correlation of more experienced reader's 3D-SPACE-based scores and consensus-based scores was perfect (kappa = 1, P < 0.001).The mean value of PC-MRI-based confidence scores were lower than those obtained in 3D-SPACE and consensus sessions. CONCLUSIONS: T2W 3D-SPACE sequence provides morphologic cerebrospinal fluid flow data. It is a noninvasive technique providing extensive multiplanar reformatted images with a lower specific absorption rate. These advantages over PC-MRI make 3D-SPACE sequence a promising tool in management of patients with hydrocephalus. FAU - Kartal, Merve Gulbiz AU - Kartal MG AD - From the *Department of Radiology, Ataturk Training and Research Hospital, Ankara; daggerDepartment of Biostatistics, Uludag University, Medical Faculty, Gorukle, Bursa; and double daggerBilkent University, National MR Research Center (UMRAM), Bilkent, Ankara, Turkey. FAU - Ocakoglu, Gokhan AU - Ocakoglu G FAU - Algin, Oktay AU - Algin O LA - eng PT - Journal Article PL - United States TA - J Comput Assist Tomogr JT - Journal of computer assisted tomography JID - 7703942 SB - IM MH - Adolescent MH - Adult MH - Aged MH - *Algorithms MH - Child MH - Feasibility Studies MH - Humans MH - Hydrocephalus/*pathology MH - Image Enhancement/*methods MH - Image Interpretation, Computer-Assisted/*methods MH - Imaging, Three-Dimensional/*methods MH - Magnetic Resonance Imaging/*methods MH - Male MH - Middle Aged MH - Reproducibility of Results MH - Sensitivity and Specificity MH - *Signal Processing, Computer-Assisted MH - Young Adult EDAT- 2015/05/16 06:00 MHDA- 2015/07/29 06:00 CRDT- 2015/05/16 06:00 PHST- 2015/05/16 06:00 [entrez] PHST- 2015/05/16 06:00 [pubmed] PHST- 2015/07/29 06:00 [medline] AID - 00004728-201505000-00005 [pii] AID - 10.1097/RCT.0000000000000206 [doi] PST - ppublish SO - J Comput Assist Tomogr. 2015 May-Jun;39(3):321-8. doi: 10.1097/RCT.0000000000000206.