PMID- 25980046
OWN - NLM
STAT- MEDLINE
DCOM- 20150817
LR  - 20151008
IS  - 0029-0203 (Print)
IS  - 0029-0203 (Linking)
VI  - 119
IP  - 4
DP  - 2015 Apr
TI  - [Multimodal imaging of a case of acute syphilitic posterior placoid 
      chorioretinitis].
PG  - 266-72
AB  - BACKGROUND: Acute syphilitic posterior placoid chorioretinitis (ASPPC) is a rare 
      manifestation of ocular syphilis. We report on multimodal imaging including 
      ophthalmoscopy, spectral-domain optical coherence tomography (SD-OCT), 
      fluorescein angiography (FA) and indocyanine green angiography (IA) of a case 
      diagnosed with ASPPC. CASE: A 45-year-old man who was positive for human 
      immunodeficiency virus presented with a 2-week history of visual loss in the 
      right eye. CLINICAL FINDINGS: Ophthalmoscopy showed a unilateral yellowish lesion 
      involving the macula. SD-OCT revealed absence of the photoreceptor inner segment 
      ellipsoid as well as an absent external limiting membrane, and nodular elevations 
      of the retinal pigment epithelium layer at the macula. Late IA demonstrated 
      punctate hypofluorescent dots in diffuse hyperfluorescent area corresponding to 
      the macular lesion. Serologic tests were positive for syphilis and the patient 
      was treated with intravenous penicillin G. Visual acuity improved with treatment 
      from 20/100 to 20/16 and the retinal appearance returned to normal. There was 
      completely restored stratification of the outer retina after therapy. CONCLUSION: 
      In the present case of ASPPC, the SD-OCT imaging demonstrated characteristic 
      abnormalities including RPE nodularity which showed hypofluorescent dots on late 
      IA.
FAU - Sekine, Yumi
AU  - Sekine Y
FAU - Yashiro, Shigeko
AU  - Yashiro S
FAU - O'hira, Aya
AU  - O'hira A
FAU - Yoshida, Natsuyo
AU  - Yoshida N
FAU - Morinaga, Masahiro
AU  - Morinaga M
FAU - Nagashima, Nanako
AU  - Nagashima N
FAU - Katai, Naomichi
AU  - Katai N
LA  - jpn
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Nippon Ganka Gakkai Zasshi
JT  - Nippon Ganka Gakkai zasshi
JID - 7505716
RN  - Q42T66VG0C (Penicillin G)
SB  - IM
MH  - Acute Disease
MH  - Angiography
MH  - Chorioretinitis/*diagnosis/drug therapy
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multimodal Imaging
MH  - Ophthalmoscopy
MH  - Penicillin G/therapeutic use
MH  - Syphilis/*diagnosis/drug therapy
EDAT- 2015/05/20 06:00
MHDA- 2015/08/19 06:00
CRDT- 2015/05/19 06:00
PHST- 2015/05/19 06:00 [entrez]
PHST- 2015/05/20 06:00 [pubmed]
PHST- 2015/08/19 06:00 [medline]
PST - ppublish
SO  - Nippon Ganka Gakkai Zasshi. 2015 Apr;119(4):266-72.