PMID- 25980858 OWN - NLM STAT- MEDLINE DCOM- 20170424 LR - 20170424 IS - 1879-8365 (Electronic) IS - 0926-9630 (Linking) VI - 211 DP - 2015 TI - A generic architecture for an adaptive, interoperable and intelligent type 2 diabetes mellitus care system. PG - 121-31 AB - Chronic diseases such as Type 2 Diabetes Mellitus (T2DM) constitute a big burden to the global health economy. T2DM Care Management requires a multi-disciplinary and multi-organizational approach. Because of different languages and terminologies, education, experiences, skills, etc., such an approach establishes a special interoperability challenge. The solution is a flexible, scalable, business-controlled, adaptive, knowledge-based, intelligent system following a systems-oriented, architecture-centric, ontology-based and policy-driven approach. The architecture of real systems is described, using the basics and principles of the Generic Component Model (GCM). For representing the functional aspects of a system the Business Process Modeling Notation (BPMN) is used. The system architecture obtained is presented using a GCM graphical notation, class diagrams and BPMN diagrams. The architecture-centric approach considers the compositional nature of the real world system and its functionalities, guarantees coherence, and provides right inferences. The level of generality provided in this paper facilitates use case specific adaptations of the system. By that way, intelligent, adaptive and interoperable T2DM care systems can be derived from the presented model as presented in another publication. FAU - Uribe, Gustavo A AU - Uribe GA AD - Telematics Engineering Research Group, University of Cauca, Colombia. FAU - Blobel, Bernd AU - Blobel B AD - Medical Faculty, University of Regensburg, Germany. FAU - Lopez, Diego M AU - Lopez DM AD - Telematics Engineering Research Group, University of Cauca, Colombia. FAU - Schulz, Stefan AU - Schulz S AD - Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Austria. LA - eng PT - Journal Article PL - Netherlands TA - Stud Health Technol Inform JT - Studies in health technology and informatics JID - 9214582 MH - Diabetes Mellitus, Type 2/*therapy MH - *Disease Management MH - Humans MH - Information Systems/*organization & administration MH - *Software Design MH - *Systems Integration EDAT- 2015/05/20 06:00 MHDA- 2017/04/25 06:00 CRDT- 2015/05/19 06:00 PHST- 2015/05/19 06:00 [entrez] PHST- 2015/05/20 06:00 [pubmed] PHST- 2017/04/25 06:00 [medline] PST - ppublish SO - Stud Health Technol Inform. 2015;211:121-31.