PMID- 25980925
OWN - NLM
STAT- MEDLINE
DCOM- 20160408
LR  - 20161125
IS  - 1878-0938 (Electronic)
IS  - 1878-0938 (Linking)
VI  - 16
IP  - 4
DP  - 2015 Jun
TI  - In-vivo iMap IVUS comparison of in-stent neointima and native coronary 
      atherosclerosis.
PG  - 233-6
LID - S1553-8389(15)00099-8 [pii]
LID - 10.1016/j.carrev.2015.04.002 [doi]
AB  - PURPOSE: The purpose of this study was to compare plaque characteristics of 
      native coronary atherosclerosis and in-stent neointima ten months after ST 
      elevation myocardial infarction (STEMI) using iMap intravascular ultrasound 
      (IVUS). METHODS: In 49 patients in-stent neointima and the coronary segment 
      proximal to the stent were analyzed with iMap intravascular ultrasound (IVUS) ten 
      months after primary PCI for STEMI. RESULTS: A higher percentage of necrotic 
      tissue was observed in the proximal coronary segment compared to the in-stent 
      neointima by iMap IVUS (25.5% +/- 12.8% vs 12.3% +/- 3.3%, p < 0.0001) ten months 
      after STEMI. The proportion of fibrotic tissue in the proximal segment was lower 
      (63.6% +/- 14.8% vs 72.0% +/- 5.7%, p = 0.002) and the proportion of the lipidic 
      tissue was higher (8.8% +/- 3.0% vs 5.9% +/- 2.0%, p < 0.0001) than in-stent 
      neointima. CONCLUSIONS: In patients ten months after STEMI, in-stent neointima 
      contained a higher proportion of fibrotic tissue and lower proportion of necrotic 
      and lipidic tissue compared the native atherosclerotic lesion.
CI  - Copyright (c) 2015 Elsevier Inc. All rights reserved.
FAU - Trusinskis, Karlis
AU  - Trusinskis K
AD  - Latvian Centre of Cardiology, Pauls Stradins Clinical University Hospital, Riga, 
      Latvia; Faculty of Medicine, Riga Stradins University, Riga, Latvia. Electronic 
      address: cardio@inbox.lv.
FAU - Strenge, Karlis
AU  - Strenge K
AD  - Latvian Centre of Cardiology, Pauls Stradins Clinical University Hospital, Riga, 
      Latvia. Electronic address: karlis.strenge@gmail.com.
FAU - Juhnevica, Dace
AU  - Juhnevica D
AD  - Latvian Centre of Cardiology, Pauls Stradins Clinical University Hospital, Riga, 
      Latvia.
FAU - Erglis, Andrejs
AU  - Erglis A
AD  - Latvian Centre of Cardiology, Pauls Stradins Clinical University Hospital, Riga, 
      Latvia.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20150416
PL  - United States
TA  - Cardiovasc Revasc Med
JT  - Cardiovascular revascularization medicine : including molecular interventions
JID - 101238551
SB  - IM
MH  - Adult
MH  - Aged
MH  - Coronary Angiography/methods
MH  - Coronary Artery Disease/*diagnostic imaging
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/diagnostic imaging
MH  - Neointima/*diagnostic imaging
MH  - Percutaneous Coronary Intervention
MH  - Plaque, Atherosclerotic/*diagnostic imaging/pathology
MH  - *Stents
MH  - Ultrasonography, Interventional/methods
OTO - NOTNLM
OT  - iMap IVUS
OT  - neointima
OT  - tissue characterization
EDAT- 2015/05/20 06:00
MHDA- 2016/04/09 06:00
CRDT- 2015/05/19 06:00
PHST- 2015/01/25 00:00 [received]
PHST- 2015/03/27 00:00 [revised]
PHST- 2015/04/03 00:00 [accepted]
PHST- 2015/05/19 06:00 [entrez]
PHST- 2015/05/20 06:00 [pubmed]
PHST- 2016/04/09 06:00 [medline]
AID - S1553-8389(15)00099-8 [pii]
AID - 10.1016/j.carrev.2015.04.002 [doi]
PST - ppublish
SO  - Cardiovasc Revasc Med. 2015 Jun;16(4):233-6. doi: 10.1016/j.carrev.2015.04.002. 
      Epub 2015 Apr 16.