PMID- 25985122
OWN - NLM
STAT- MEDLINE
DCOM- 20160912
LR  - 20150810
IS  - 1873-3557 (Electronic)
IS  - 1386-1425 (Linking)
VI  - 149
DP  - 2015
TI  - An on-line spectrophotometric determination of trace amounts of thiourea in tap 
      water, orange juice, and orange peel samples using multi-channel flow injection 
      analysis.
PG  - 580-7
LID - S1386-1425(15)00582-X [pii]
LID - 10.1016/j.saa.2015.04.110 [doi]
AB  - In this work, a flow injection analysis (FIA) method was introduced for the 
      determination of trace amounts of thiourea in tap water. This method is based 
      upon the inhibition effect of thiourea on the reaction between meta-cresol purple 
      (MCP) and potassium bromate catalyzed by bromide ions in a sulfuric acid medium. 
      In the presence of thiourea, an induction period appears in the reaction system, 
      and as a result, the absorbance of MCP increases at 525 nm in the FIA manifold. 
      The chemical and FIA variables are studied and optimized using the univariate and 
      Simplex optimization methods. Under the optimum conditions, thiourea can be 
      determined in the range of 0.100-13.0 mug mL(-1). The limit of detection (3sigma) for 
      thiourea was found to be 0.0310 mug mL(-1). The relative standard deviations 
      (RSDs) for six replicate determinations of 0.500, 5.00, and 12.0 mug mL(-1) of 
      thiourea were 4.0%, 1.8%, and 1.2%, respectively. The proposed method was also 
      applied for the determination of thiourea in orange juice and orange peel samples 
      with recoveries in the range of 98.0-101%. The analytical speed of the method was 
      calculated to be about 120 sample per hour.
CI  - Copyright (c) 2015 Elsevier B.V. All rights reserved.
FAU - Arab Chamjangali, M
AU  - Arab Chamjangali M
AD  - Department of Chemistry, Shahrood University, Shahrood, P.O. Box 36155-316, Iran. 
      Electronic address: marab@shahroodut.ac.ir.
FAU - Goudarzi, N
AU  - Goudarzi N
AD  - Department of Chemistry, Shahrood University, Shahrood, P.O. Box 36155-316, Iran.
FAU - Ghochani Moghadam, A
AU  - Ghochani Moghadam A
AD  - Department of Chemistry, Shahrood University, Shahrood, P.O. Box 36155-316, Iran.
FAU - Amin, A H
AU  - Amin AH
AD  - Department of Chemistry, Shahrood University, Shahrood, P.O. Box 36155-316, Iran.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150508
PL  - England
TA  - Spectrochim Acta A Mol Biomol Spectrosc
JT  - Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
JID - 9602533
RN  - 0 (Bromates)
RN  - 0 (Bromides)
RN  - 0 (Indicators and Reagents)
RN  - 0 (Potassium Compounds)
RN  - 0 (Sulfuric Acids)
RN  - 04MB35W6ZA (potassium bromate)
RN  - 059QF0KO0R (Water)
RN  - GYV9AM2QAG (Thiourea)
RN  - O40UQP6WCF (sulfuric acid)
RN  - OSD78555ZM (potassium bromide)
SB  - IM
MH  - Beverages/*analysis
MH  - Bromates/analysis
MH  - Bromides/analysis
MH  - Citrus sinensis/*chemistry
MH  - Flow Injection Analysis/*methods
MH  - Indicators and Reagents
MH  - *Online Systems
MH  - Osmolar Concentration
MH  - Potassium Compounds/analysis
MH  - Rheology
MH  - Spectrophotometry/*methods
MH  - Sulfuric Acids/analysis
MH  - Temperature
MH  - Thiourea/*analysis
MH  - Water/*chemistry
OTO - NOTNLM
OT  - Flow injection analysis (FIA)
OT  - Induction period
OT  - Meta-cresol purple (MCP)
OT  - Simplex optimization
OT  - Spectrophotometry
OT  - Thiourea
EDAT- 2015/05/20 06:00
MHDA- 2016/09/13 06:00
CRDT- 2015/05/19 06:00
PHST- 2014/10/28 00:00 [received]
PHST- 2015/02/04 00:00 [revised]
PHST- 2015/04/29 00:00 [accepted]
PHST- 2015/05/19 06:00 [entrez]
PHST- 2015/05/20 06:00 [pubmed]
PHST- 2016/09/13 06:00 [medline]
AID - S1386-1425(15)00582-X [pii]
AID - 10.1016/j.saa.2015.04.110 [doi]
PST - ppublish
SO  - Spectrochim Acta A Mol Biomol Spectrosc. 2015;149:580-7. doi: 
      10.1016/j.saa.2015.04.110. Epub 2015 May 8.