PMID- 25986102
OWN - NLM
STAT- MEDLINE
DCOM- 20150917
LR  - 20220408
IS  - 1552-6259 (Electronic)
IS  - 0003-4975 (Linking)
VI  - 100
IP  - 1
DP  - 2015 Jul
TI  - Sublocalization of Cardiac Involvement in Sarcoidosis and Surgical Exclusion in 
      Patients With Congestive Heart Failure.
PG  - 81-7
LID - S0003-4975(15)00251-9 [pii]
LID - 10.1016/j.athoracsur.2015.02.043 [doi]
AB  - BACKGROUND: In sarcoidosis, cardiac involvement can cause fatal conditions such 
      as left ventricular (LV) dysfunction and rhythm disturbance. We surgically 
      treated critical patients with congestive heart failure due to cardiac 
      sarcoidosis. METHODS: During 14 years, 384 patients with nonischemic dilated 
      cardiomyopathy were operated. Among them, 14 patients (3.6%) with New York Heart 
      Association (NYHA) class IV (male/female, 3/11; 57 +/- 11 years) caused by 
      sarcoidosis underwent surgery (elective/emergent, 12/2). The akinetic lesion, as 
      identified by speckle-tracking echocardiography, was excluded. RESULTS: 
      Localization of akinetic lesions was achieved in 13 patients (93%). In the short 
      axis, lesional distribution was higher in the anterior (62%) and septal segments 
      (54%) when compared with the posterior (31%) and lateral segments (23%). Along 
      the long axis, regional distribution was higher in the mid (85%) and apical 
      segments (69%) when compared with the basal segment (31%). The main lesions were 
      excluded by septal anterior ventricular exclusion (n = 5), posterior restoration 
      procedure (n = 3), endoventricular circular patch plasty (n = 3), and linear 
      resection (n = 2). Mitral valve surgery included mitral valve plasty (n = 7) and 
      replacement (n = 7). In patients undergoing elective surgery, early results 
      showed that 10 patients survived (83%) and NYHA class improved (6 patients in 
      class II and 4 in class III). Patients who underwent emergent surgery did not 
      survive. The observation period was 55 +/- 59 months in survivors. During 
      follow-up, 4 patients died after 42 +/- 48 months. The other 5 patients have 
      survived for 71 +/- 61 months. The 3- and 5-year survival rates were 65% and 52%, 
      respectively. CONCLUSIONS: Sarcoidosis can result in sublocalized LV involvement, 
      which can be surgically excluded.
CI  - Copyright (c) 2015 The Society of Thoracic Surgeons. Published by Elsevier Inc. All 
      rights reserved.
FAU - Hirota, Masanori
AU  - Hirota M
AD  - Department of Cardiovascular Surgery, Hayama Heart Center, Kanagawa, Japan. 
      Electronic address: hirota@hayamaheart.gr.jp.
FAU - Yoshida, Minoru
AU  - Yoshida M
AD  - Department of Cardiovascular Surgery, Hayama Heart Center, Kanagawa, Japan.
FAU - Hoshino, Joji
AU  - Hoshino J
AD  - Department of Cardiovascular Surgery, Hayama Heart Center, Kanagawa, Japan.
FAU - Kondo, Taichi
AU  - Kondo T
AD  - Department of Cardiovascular Surgery, Hayama Heart Center, Kanagawa, Japan.
FAU - Isomura, Tadashi
AU  - Isomura T
AD  - Department of Cardiovascular Surgery, Hayama Heart Center, Kanagawa, Japan.
LA  - eng
PT  - Journal Article
DEP - 20150516
PL  - Netherlands
TA  - Ann Thorac Surg
JT  - The Annals of thoracic surgery
JID - 15030100R
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cardiac Surgical Procedures/methods
MH  - Cardiomyopathies/*complications/pathology
MH  - Female
MH  - Heart Failure/*etiology/*surgery
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Sarcoidosis/*complications/pathology
EDAT- 2015/05/20 06:00
MHDA- 2015/09/18 06:00
CRDT- 2015/05/20 06:00
PHST- 2014/11/25 00:00 [received]
PHST- 2015/02/10 00:00 [revised]
PHST- 2015/02/12 00:00 [accepted]
PHST- 2015/05/20 06:00 [entrez]
PHST- 2015/05/20 06:00 [pubmed]
PHST- 2015/09/18 06:00 [medline]
AID - S0003-4975(15)00251-9 [pii]
AID - 10.1016/j.athoracsur.2015.02.043 [doi]
PST - ppublish
SO  - Ann Thorac Surg. 2015 Jul;100(1):81-7. doi: 10.1016/j.athoracsur.2015.02.043. 
      Epub 2015 May 16.