PMID- 25994129
OWN - NLM
STAT- MEDLINE
DCOM- 20151208
LR  - 20220409
IS  - 1471-2458 (Electronic)
IS  - 1471-2458 (Linking)
VI  - 15
DP  - 2015 May 22
TI  - Prevalence of HIV and syphilis infections among pregnant women attending 
      antenatal clinics in Tanzania, 2011.
PG  - 501
LID - 10.1186/s12889-015-1848-5 [doi]
LID - 501
AB  - BACKGROUND: The occurrence of HIV-1 and syphilis infections during pregnancy 
      poses major health risks to the foetus due to mother-to-child transmission. We 
      conducted surveillance of HIV and syphilis infections among pregnant women 
      attending antenatal clinics (ANCs) in Mainland Tanzania in 2011. METHODS: This 
      surveillance was carried out in 133 ANCs selected from 21 regions in Tanzania. In 
      each region, six ANC sites were selected, with urban, semi-urban, and rural areas 
      contributing two each. All pregnant women who were attending selected sentinel 
      ANC sites for the first time at any pregnancy between September and December 2011 
      were enrolled. Serial ELISA assays were performed to detect HIV infection in an 
      unlinked anonymous manner using dried blood spot (DBS) after routine syphilis 
      testing. Data analysis was conducted using Stata v.12 software. RESULTS: A total 
      of 39,698 pregnant women representing 2.4 % of all pregnant women (1.68 million) 
      attending ANCs in the Mainland Tanzania were enrolled. The overall HIV prevalence 
      was found to be 5.6 % (95 % CI: 5.4-5.8 %). The risk for HIV infection was 
      significantly higher among women aged 25-34 (cOR = 1.97, 95 % CI: 1.79-2.16; p < 
      0.05), older than 35 years (cOR = 1.88, 95 % CI: 1.62-2.17; p < 0.05) and those 
      having 1-2 and 3-4 previous pregnancies. HIV infection was less prevalent among 
      women attending rural ANC clinics (cOR = 0.46, 95 % CI 0.4-0.52; p < 0.05). The 
      overall syphilis prevalence was 2.5 % (95 % CI: 2.3, 3.6). The risk for syphilis 
      infection was significantly higher among women attending semi-urban and rural 
      clinics and those having 3-4, and 5 previous pregnancies (p < 0.05). Marital 
      status and level of education were not statistically significant with either of 
      the two infections. HIV and syphilis co-infections occurred in 109 of 38,928 (0.3 
      %). CONCLUSION: The overall prevalence of HIV infection (5.6 %) and syphilis (2.5 
      %) found among pregnant women attending ANC clinics in Tanzania calls for further 
      strengthening of current intervention measures, which include scaling up the 
      integration of prevention of mother to child transmission (PMTCT) services in 
      Reproductive and Child Health (RCH) clinics.
FAU - Manyahi, Joel
AU  - Manyahi J
AD  - Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania. 
      manyahijoel@yahoo.com.
FAU - Jullu, Boniphace S
AU  - Jullu BS
AD  - St. Francis University College of Health and Allied Sciences, Ifakara, Tanzania. 
      jullub@gmail.com.
FAU - Abuya, Mathias I
AU  - Abuya MI
AD  - National AIDS Control Programme, Dar es Salaam, Tanzania. mattyabuya@yahoo.com.
FAU - Juma, James
AU  - Juma J
AD  - National AIDS Control Programme, Dar es Salaam, Tanzania. jj162us@gmail.com.
FAU - Ndayongeje, Joel
AU  - Ndayongeje J
AD  - National AIDS Control Programme, Dar es Salaam, Tanzania. 
      ndayongejej@yahoo.co.uk.
FAU - Kilama, Bonita
AU  - Kilama B
AD  - National AIDS Control Programme, Dar es Salaam, Tanzania. bonitakilama@yahoo.com.
FAU - Sambu, Veryeh
AU  - Sambu V
AD  - National AIDS Control Programme, Dar es Salaam, Tanzania. veryeh77@hotmail.com.
FAU - Nondi, Josef
AU  - Nondi J
AD  - National AIDS Control Programme, Dar es Salaam, Tanzania. josenondi@yahoo.co.uk.
FAU - Rabiel, Bernard
AU  - Rabiel B
AD  - National AIDS Control Programme, Dar es Salaam, Tanzania. benrabiel@yahoo.co.uk.
FAU - Somi, Geoffrey
AU  - Somi G
AD  - National AIDS Control Programme, Dar es Salaam, Tanzania. Geoffreysomi@gmail.com.
FAU - Matee, Mecky I
AU  - Matee MI
AD  - Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania. 
      mateemecky@yahoo.com.
LA  - eng
PT  - Journal Article
DEP - 20150522
PL  - England
TA  - BMC Public Health
JT  - BMC public health
JID - 100968562
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Female
MH  - HIV Infections/*epidemiology
MH  - Humans
MH  - Marital Status
MH  - Parity
MH  - Pregnancy
MH  - Pregnancy Complications, Infectious/*epidemiology
MH  - Prenatal Care
MH  - Prevalence
MH  - Rural Population
MH  - Syphilis/*epidemiology
MH  - Tanzania/epidemiology
MH  - Young Adult
PMC - PMC4492104
EDAT- 2015/05/24 06:00
MHDA- 2015/12/15 06:00
PMCR- 2015/05/22
CRDT- 2015/05/22 06:00
PHST- 2014/10/08 00:00 [received]
PHST- 2015/05/18 00:00 [accepted]
PHST- 2015/05/22 06:00 [entrez]
PHST- 2015/05/24 06:00 [pubmed]
PHST- 2015/12/15 06:00 [medline]
PHST- 2015/05/22 00:00 [pmc-release]
AID - 10.1186/s12889-015-1848-5 [pii]
AID - 1848 [pii]
AID - 10.1186/s12889-015-1848-5 [doi]
PST - epublish
SO  - BMC Public Health. 2015 May 22;15:501. doi: 10.1186/s12889-015-1848-5.