PMID- 25994961
OWN - NLM
STAT- MEDLINE
DCOM- 20170306
LR  - 20191210
IS  - 1460-2199 (Electronic)
IS  - 1047-3211 (Print)
IS  - 1047-3211 (Linking)
VI  - 26
IP  - 6
DP  - 2016 Jun
TI  - Individual Differences in Reward and Somatosensory-Motor Brain Regions Correlate 
      with Adiposity in Adolescents.
PG  - 2602-11
LID - 10.1093/cercor/bhv097 [doi]
AB  - The prevalence of adolescent obesity has increased dramatically over the past 
      three decades, and research has documented that the number of television shows 
      viewed during childhood is associated with greater risk for obesity. In 
      particular, considerable evidence suggests that exposure to food marketing 
      promotes eating habits that contribute to obesity. The present study examines 
      neural responses to dynamic food commercials in overweight and healthy-weight 
      adolescents using functional magnetic resonance imaging (fMRI). Compared with 
      non-food commercials, food commercials more strongly engaged regions involved in 
      attention and saliency detection (occipital lobe, precuneus, superior temporal 
      gyri, and right insula) and in processing rewards [left and right nucleus 
      accumbens (NAcc) and left orbitofrontal cortex (OFC)]. Activity in the left OFC 
      and right insula further correlated with subjects' percent body fat at the time 
      of the scan. Interestingly, this reward-related activity to food commercials was 
      accompanied by the additional recruitment of mouth-specific somatosensory-motor 
      cortices-a finding that suggests the intriguing possibility that higher-adiposity 
      adolescents mentally simulate eating behaviors and offers a potential neural 
      mechanism for the formation and reinforcement of unhealthy eating habits that may 
      hamper an individual's ability lose weight later in life.
CI  - (c) The Author 2015. Published by Oxford University Press. All rights reserved. For 
      Permissions, please e-mail: journals.permissions@oup.com.
FAU - Rapuano, Kristina M
AU  - Rapuano KM
AD  - Department of Psychological and Brain Sciences, Dartmouth College, Hanover NH, 
      USA.
FAU - Huckins, Jeremy F
AU  - Huckins JF
AD  - Department of Psychological and Brain Sciences, Dartmouth College, Hanover NH, 
      USA.
FAU - Sargent, James D
AU  - Sargent JD
AD  - Norris Cotton Cancer Center, Dartmouth Hitchcock Medical Center, Lebanon NH, USA.
FAU - Heatherton, Todd F
AU  - Heatherton TF
AD  - Department of Psychological and Brain Sciences, Dartmouth College, Hanover NH, 
      USA.
FAU - Kelley, William M
AU  - Kelley WM
AD  - Department of Psychological and Brain Sciences, Dartmouth College, Hanover NH, 
      USA.
LA  - eng
GR  - P30 CA023108/CA/NCI NIH HHS/United States
GR  - R01 DA022582/DA/NIDA NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20150520
PL  - United States
TA  - Cereb Cortex
JT  - Cerebral cortex (New York, N.Y. : 1991)
JID - 9110718
SB  - IM
MH  - Adolescent
MH  - *Advertising
MH  - Brain/*physiopathology
MH  - Brain Mapping
MH  - Child
MH  - Cohort Studies
MH  - Female
MH  - Food
MH  - Humans
MH  - *Individuality
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Motion Perception/*physiology
MH  - Neuropsychological Tests
MH  - Obesity/*physiopathology/psychology
MH  - Photic Stimulation/methods
MH  - *Reward
MH  - Television
PMC - PMC4869807
OTO - NOTNLM
OT  - action observation
OT  - advertising
OT  - fMRI
OT  - food
OT  - obesity
EDAT- 2015/05/23 06:00
MHDA- 2017/03/07 06:00
PMCR- 2017/06/01
CRDT- 2015/05/22 06:00
PHST- 2015/05/22 06:00 [entrez]
PHST- 2015/05/23 06:00 [pubmed]
PHST- 2017/03/07 06:00 [medline]
PHST- 2017/06/01 00:00 [pmc-release]
AID - bhv097 [pii]
AID - 10.1093/cercor/bhv097 [doi]
PST - ppublish
SO  - Cereb Cortex. 2016 Jun;26(6):2602-11. doi: 10.1093/cercor/bhv097. Epub 2015 May 
      20.