PMID- 25995492
OWN - NLM
STAT- MEDLINE
DCOM- 20150727
LR  - 20191210
IS  - 1535-1386 (Electronic)
IS  - 0021-9355 (Linking)
VI  - 97
IP  - 10
DP  - 2015 May 20
TI  - Minimal clinically important difference and the effect of clinical variables on 
      the ankle osteoarthritis scale in surgically treated end-stage ankle arthritis.
PG  - 818-23
LID - 10.2106/JBJS.N.00147 [doi]
AB  - BACKGROUND: There is much debate regarding the best outcome tool for use in foot 
      and ankle surgery, specifically in patients with ankle arthritis. The Ankle 
      Osteoarthritis Scale (AOS) is a validated, disease-specific score. The goals of 
      this study were to investigate the clinical performance of the AOS and to 
      determine a minimal clinically important difference (MCID) for it, using a large 
      cohort of 238 patients undergoing surgery for end-stage ankle arthritis. METHODS: 
      Patients treated with total ankle arthroplasty or ankle arthrodesis were 
      prospectively followed for a minimum of two years at a single site. Data on 
      demographics, comorbidities, AOS score, Short Form-36 results, and the 
      relationship between expectations and satisfaction were collected at baseline 
      (preoperatively), at six and twelve months, and then yearly thereafter. A linear 
      regression analysis examined the variables affecting the change in AOS scores 
      between baseline and the two-year follow-up. An MCID in the AOS change score was 
      then determined by employing an anchor question, which asked patients to rate 
      their relief from symptoms after surgery. RESULTS: Surgical treatment of 
      end-stage ankle arthritis resulted in a mean improvement (and standard deviation) 
      of 31.2 +/- 22.7 points in the AOS score two years after surgery. The MCID of the 
      AOS change score was a mean of 28.0 +/- 17.9 points. The change in AOS score was 
      significantly affected by the preoperative AOS score, smoking, back pain, and 
      age. CONCLUSIONS: Patients undergoing arthroplasty or arthrodesis for end-stage 
      ankle arthritis experienced a mean improvement in AOS score that was greater than 
      the estimated MCID (31.2 versus 28.0 points).
CI  - Copyright (c) 2015 by The Journal of Bone and Joint Surgery, Incorporated.
FAU - Coe, Marcus P
AU  - Coe MP
AD  - Department of Orthopaedic Surgery, Dartmouth-Hitchcock Medical Center, One 
      Medical Center Drive, Lebanon, NH 03756.
FAU - Sutherland, Jason M
AU  - Sutherland JM
AD  - Centre for Health Services and Policy Research, School of Population and Public 
      Health, University of British Columbia, 201-2206 East Mall, Vancouver, BC V6T 
      1Z3, Canada.
FAU - Penner, Murray J
AU  - Penner MJ
AD  - Department of Orthopaedics, University of British Columbia, 1000-1200 Burrard 
      Street, Vancouver, BC V6Z 2C7, Canada.
FAU - Younger, Alastair
AU  - Younger A
AD  - Department of Orthopedics, University of British Columbia, 560-1144 Burrard 
      Street, Vancouver, BC V6Z 2A5, Canada.
FAU - Wing, Kevin J
AU  - Wing KJ
AD  - Department of Orthopaedics, University of British Columbia, 1000-1200 Burrard 
      Street, Vancouver, BC V6Z 2C7, Canada.
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PL  - United States
TA  - J Bone Joint Surg Am
JT  - The Journal of bone and joint surgery. American volume
JID - 0014030
SB  - IM
MH  - Aged
MH  - Ankle Joint/surgery
MH  - *Arthroplasty, Replacement, Ankle
MH  - Arthroscopy
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Osteoarthritis/physiopathology/*surgery
MH  - Prospective Studies
MH  - Range of Motion, Articular/physiology
MH  - Retrospective Studies
MH  - Severity of Illness Index
MH  - Surveys and Questionnaires
MH  - Treatment Outcome
EDAT- 2015/05/23 06:00
MHDA- 2015/07/28 06:00
CRDT- 2015/05/22 06:00
PHST- 2015/05/22 06:00 [entrez]
PHST- 2015/05/23 06:00 [pubmed]
PHST- 2015/07/28 06:00 [medline]
AID - 97/10/818 [pii]
AID - 10.2106/JBJS.N.00147 [doi]
PST - ppublish
SO  - J Bone Joint Surg Am. 2015 May 20;97(10):818-23. doi: 10.2106/JBJS.N.00147.