PMID- 25997658
OWN - NLM
STAT- MEDLINE
DCOM- 20160324
LR  - 20210409
IS  - 1421-9832 (Electronic)
IS  - 1018-8665 (Linking)
VI  - 231
IP  - 1
DP  - 2015
TI  - Pityriasis Rosea in Children: Clinical Features and Laboratory Investigations.
PG  - 9-14
LID - 10.1159/000381285 [doi]
AB  - Pityriasis rosea (PR) is a common, self-limiting exanthematous disease associated 
      with a systemic reactivation of human herpesvirus 6 (HHV-6) and/or HHV-7. It 
      usually occurs in the second or third decade of life whereas it is uncommon in 
      patients younger than 10 years. We studied the clinical features and virological 
      parameters of 31 children with PR, comparing them with those in adults. Our 
      findings indicate that PR presents different characteristics between children and 
      adults, mainly consisting of time lapse between herald patch and generalized 
      eruption, duration of the exanthem, oropharyngeal involvement and persistence of 
      HHV-6 and HHV-7 plasma viremia. Overall, these results suggest that, following 
      HHV-6 and/or HHV-7 systemic active infection, the pathogenetic mechanisms 
      involved in PR may at least partly be different in children and adults.
CI  - (c) 2015 S. Karger AG, Basel.
FAU - Drago, Francesco
AU  - Drago F
AD  - Department of Dermatology, DISSAL, IRCCS A.O.U. San Martino-IST, Genoa, Italy.
FAU - Ciccarese, Giulia
AU  - Ciccarese G
FAU - Broccolo, Francesco
AU  - Broccolo F
FAU - Cozzani, Emanuele
AU  - Cozzani E
FAU - Parodi, Aurora
AU  - Parodi A
LA  - eng
PT  - Journal Article
DEP - 20150512
PL  - Switzerland
TA  - Dermatology
JT  - Dermatology (Basel, Switzerland)
JID - 9203244
RN  - 0 (Antibodies, Viral)
RN  - 0 (DNA, Viral)
RN  - 0 (Immunoglobulin G)
RN  - 0 (Immunoglobulin M)
SB  - IM
MH  - Antibodies, Viral/blood
MH  - Child
MH  - Child, Preschool
MH  - DNA, Viral/*blood
MH  - Female
MH  - *Herpesvirus 6, Human/immunology
MH  - *Herpesvirus 7, Human/immunology
MH  - Humans
MH  - Immunoglobulin G/blood
MH  - Immunoglobulin M/blood
MH  - Male
MH  - Mouth Diseases/pathology/virology
MH  - Pityriasis Rosea/*pathology/*virology
MH  - Roseolovirus Infections/*complications
MH  - Time Factors
MH  - Viral Load
MH  - Viremia/complications
EDAT- 2015/05/23 06:00
MHDA- 2016/03/25 06:00
CRDT- 2015/05/23 06:00
PHST- 2014/11/10 00:00 [received]
PHST- 2015/02/26 00:00 [accepted]
PHST- 2015/05/23 06:00 [entrez]
PHST- 2015/05/23 06:00 [pubmed]
PHST- 2016/03/25 06:00 [medline]
AID - 000381285 [pii]
AID - 10.1159/000381285 [doi]
PST - ppublish
SO  - Dermatology. 2015;231(1):9-14. doi: 10.1159/000381285. Epub 2015 May 12.