PMID- 25998210
OWN - NLM
STAT- MEDLINE
DCOM- 20160615
LR  - 20150917
IS  - 1432-0770 (Electronic)
IS  - 0340-1200 (Linking)
VI  - 109
IP  - 4-5
DP  - 2015 Oct
TI  - Modeling neural activity with cumulative damage distributions.
PG  - 421-33
LID - 10.1007/s00422-015-0651-9 [doi]
AB  - Neurons transmit information as action potentials or spikes. Due to the inherent 
      randomness of the inter-spike intervals (ISIs), probabilistic models are often 
      used for their description. Cumulative damage (CD) distributions are a family of 
      probabilistic models that has been widely considered for describing time-related 
      cumulative processes. This family allows us to consider certain deterministic 
      principles for modeling ISIs from a probabilistic viewpoint and to link its 
      parameters to values with biological interpretation. The CD family includes the 
      Birnbaum-Saunders and inverse Gaussian distributions, which possess distinctive 
      properties and theoretical arguments useful for ISI description. We expand the 
      use of CD distributions to the modeling of neural spiking behavior, mainly by 
      testing the suitability of the Birnbaum-Saunders distribution, which has not been 
      studied in the setting of neural activity. We validate this expansion with 
      original experimental and simulated electrophysiological data.
FAU - Leiva, Victor
AU  - Leiva V
AD  - Faculty of Engineering and Sciences, Universidad Adolfo Ibanez, Vina del Mar, 
      Chile. victorleivasanchez@gmail.com.
AD  - Institute of Statistics, Universidad de Valparaiso, Valparaiso, Chile. 
      victorleivasanchez@gmail.com.
FAU - Tejo, Mauricio
AU  - Tejo M
AD  - Faculty of Natural and Exact Sciences, Universidad de Playa Ancha, Valparaiso, 
      Chile.
FAU - Guiraud, Pierre
AU  - Guiraud P
AD  - Centro de Investigacion y Modelamiento de Fenomenos Aleatorios - Valparaiso, 
      Faculty of Engineering, Universidad de Valparaiso, Valparaiso, Chile.
FAU - Schmachtenberg, Oliver
AU  - Schmachtenberg O
AD  - Centro Interdisciplinario de Neurociencia de Valparaiso and Institute of 
      Neuroscience, Universidad de Valparaiso, Valparaiso, Chile.
FAU - Orio, Patricio
AU  - Orio P
AD  - Centro Interdisciplinario de Neurociencia de Valparaiso and Institute of 
      Neuroscience, Universidad de Valparaiso, Valparaiso, Chile.
FAU - Marmolejo-Ramos, Fernando
AU  - Marmolejo-Ramos F
AD  - Gosta Ekman Laboratory, Department of Psychology, Stockholm University, 
      Stockholm, Sweden.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20150522
PL  - Germany
TA  - Biol Cybern
JT  - Biological cybernetics
JID - 7502533
SB  - IM
MH  - Action Potentials/*physiology
MH  - Animals
MH  - Computer Simulation
MH  - Female
MH  - Humans
MH  - Male
MH  - *Models, Neurological
MH  - Neurons/*physiology
MH  - Normal Distribution
OTO - NOTNLM
OT  - Birnbaum-Saunders and inverse Gaussian distributions
OT  - Integrate-and-fire model
OT  - Inter-spike intervals
OT  - Maximum likelihood method
OT  - Model selection and goodness of fit
EDAT- 2015/05/23 06:00
MHDA- 2016/06/16 06:00
CRDT- 2015/05/23 06:00
PHST- 2014/05/06 00:00 [received]
PHST- 2015/04/20 00:00 [accepted]
PHST- 2015/05/23 06:00 [entrez]
PHST- 2015/05/23 06:00 [pubmed]
PHST- 2016/06/16 06:00 [medline]
AID - 10.1007/s00422-015-0651-9 [pii]
AID - 10.1007/s00422-015-0651-9 [doi]
PST - ppublish
SO  - Biol Cybern. 2015 Oct;109(4-5):421-33. doi: 10.1007/s00422-015-0651-9. Epub 2015 
      May 22.