PMID- 26002334
OWN - NLM
STAT- MEDLINE
DCOM- 20160211
LR  - 20191210
IS  - 1873-4324 (Electronic)
IS  - 0003-2670 (Linking)
VI  - 878
DP  - 2015 Jun 9
TI  - beta-CD/ATP composite materials for use in dispersive solid-phase extraction to 
      measure (fluoro)quinolone antibiotics in honey samples.
PG  - 131-9
LID - S0003-2670(15)00450-X [pii]
LID - 10.1016/j.aca.2015.03.056 [doi]
AB  - A novel sorbent (beta-CD/ATP composite) for dispersive solid-phase extraction 
      (d-SPE) prepared by bonding beta-cyclodextrin to modified attapulgite via silane 
      coupling was used to determine the concentrations of four (fluoro)quinolones (Qs) 
      in honey samples. The subsequent quantification of the Qs (ciprofloxacin, 
      norfloxacin, ofloxacin, and gatifloxacin) was accomplished using high-performance 
      liquid chromatography (HPLC) with ultraviolet detection after the d-SPE 
      procedure. Parameters that may influence the extraction efficiency, such as type 
      and volume of the eluent, type and amount of the sorbent, times of the vortex and 
      sonication process, and pH of the sample, were investigated using batch and 
      column procedures. The optimal experimental conditions (5 mL sample at pH 3, 4 mg 
      of beta-CD/ATP composite as the sorbent, 200 muL of 40% ammonia in methanol as the 
      eluent, with vortex time 60s and sonication time 6 min, and no addition of salt) 
      were obtained from this statistical evaluation. The limits of detection (LODs) 
      were determined to the range from 0.30 to 3.95 mug L(-1). Good recoveries 
      (83.6-88.6%) were obtained under the optimum conditions, and the relative 
      standard deviations (RSDs), which are used to indicate reproducibility, were less 
      than 7.4%. The method was validated with three real honey samples, and the 
      results demonstrated that beta-CD/ATP composite possessed a high adsorption capacity 
      for Qs. Although the LODs were slightly higher than expected, this study 
      confirmed the possibility of using cyclodextrin grafted palygorskite in 
      analytical applications.
CI  - Copyright (c) 2015 Elsevier B.V. All rights reserved.
FAU - Cui, Xiangqian
AU  - Cui X
AD  - Department of Applied Chemistry, China Agricultural University, Yuanmingyuan West 
      Road 2#, Haidian District, Beijing 100194, China.
FAU - Zhang, Panjie
AU  - Zhang P
AD  - Department of Applied Chemistry, China Agricultural University, Yuanmingyuan West 
      Road 2#, Haidian District, Beijing 100194, China.
FAU - Yang, Xiaoling
AU  - Yang X
AD  - Department of Applied Chemistry, China Agricultural University, Yuanmingyuan West 
      Road 2#, Haidian District, Beijing 100194, China.
FAU - Yang, Miyi
AU  - Yang M
AD  - Department of Applied Chemistry, China Agricultural University, Yuanmingyuan West 
      Road 2#, Haidian District, Beijing 100194, China.
FAU - Zhou, Wenfeng
AU  - Zhou W
AD  - Department of Applied Chemistry, China Agricultural University, Yuanmingyuan West 
      Road 2#, Haidian District, Beijing 100194, China.
FAU - Zhang, Sanbin
AU  - Zhang S
AD  - Department of Applied Chemistry, China Agricultural University, Yuanmingyuan West 
      Road 2#, Haidian District, Beijing 100194, China.
FAU - Gao, Haixiang
AU  - Gao H
AD  - Department of Applied Chemistry, China Agricultural University, Yuanmingyuan West 
      Road 2#, Haidian District, Beijing 100194, China.
FAU - Lu, Runhua
AU  - Lu R
AD  - Department of Applied Chemistry, China Agricultural University, Yuanmingyuan West 
      Road 2#, Haidian District, Beijing 100194, China. Electronic address: 
      rhlu@cau.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Validation Study
DEP - 20150403
PL  - Netherlands
TA  - Anal Chim Acta
JT  - Analytica chimica acta
JID - 0370534
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Magnesium Compounds)
RN  - 0 (Quinolones)
RN  - 0 (Silicon Compounds)
RN  - 0 (beta-Cyclodextrins)
RN  - JV039JZZ3A (betadex)
RN  - U6V729APAM (attapulgite)
SB  - IM
MH  - Adsorption
MH  - Anti-Bacterial Agents/*isolation & purification
MH  - Chromatography, High Pressure Liquid/methods
MH  - Halogenation
MH  - Honey/*analysis
MH  - Limit of Detection
MH  - Magnesium Compounds/*chemistry
MH  - Quinolones/*isolation & purification
MH  - Reproducibility of Results
MH  - Silicon Compounds/*chemistry
MH  - Solid Phase Extraction/*methods
MH  - beta-Cyclodextrins/*chemistry
OTO - NOTNLM
OT  - (Fluoro)quinolone antibiotics
OT  - Dispersive solid-phase extraction
OT  - Honey samples
OT  - beta-CD/ATP composite
EDAT- 2015/05/24 06:00
MHDA- 2016/02/13 06:00
CRDT- 2015/05/24 06:00
PHST- 2014/11/21 00:00 [received]
PHST- 2015/03/28 00:00 [revised]
PHST- 2015/03/31 00:00 [accepted]
PHST- 2015/05/24 06:00 [entrez]
PHST- 2015/05/24 06:00 [pubmed]
PHST- 2016/02/13 06:00 [medline]
AID - S0003-2670(15)00450-X [pii]
AID - 10.1016/j.aca.2015.03.056 [doi]
PST - ppublish
SO  - Anal Chim Acta. 2015 Jun 9;878:131-9. doi: 10.1016/j.aca.2015.03.056. Epub 2015 
      Apr 3.