PMID- 26008218
OWN - NLM
STAT- MEDLINE
DCOM- 20160901
LR  - 20221207
IS  - 2210-7711 (Electronic)
VI  - 37
IP  - 5
DP  - 2015 Oct
TI  - Impact of a pharmacotherapy plan to improve adherence for patients with type-2 
      diabetes and hypertension in a Chilean hospital.
PG  - 734-8
LID - 10.1007/s11096-015-0131-2 [doi]
AB  - BACKGROUND: Non-adherence to prescribed treatment is a principle cause of 
      treatment failure in patients with chronic diseases, such as type 2 diabetes 
      mellitus (T2DM) and hypertension. Improved patient monitoring and education have 
      been shown to improve adherence and clinical outcomes. OBJECTIVE: This study 
      evaluates the impact of a pharmacotherapy optimization plan centered on patient 
      education that was implemented at a hospital in Arauco, Chile. METHODS: A 
      prospective study was conducted using 50 randomly selected patients diagnosed 
      with both T2DM and hypertension. Each patient participated in three successive 
      interview sessions over 6 months. At each session, the following variables were 
      evaluated by a pharmacist: blood pressure, HbA1c, adherence to prescribed 
      medication, and patient knowledge of disease. RESULTS: Significant decreases were 
      observed for HbA1c (<0.001), and SBP (<0.001), with stronger and more significant 
      decreases observed for females. Patient adherence to prescribed medication also 
      improved, but not significantly. The number of patients with full knowledge of 
      their diseases increased significantly (p < 0.001) from 10 to 66%. CONCLUSION: 
      This study suggests that the incorporation of a pharmacotherapeutic optimization 
      plan for patients with chronic diseases can have a positive impact on the control 
      of chronic diseases, such as T2DM and hypertension.
FAU - Soto, Alejandra
AU  - Soto A
AD  - CESFAM Bicentenario, Arauco, Chile.
FAU - Avila, Ximena
AU  - Avila X
AD  - Pharmacovigilance Unit, San Vicente Hospital, Arauco, Chile.
FAU - Cordova, Pia
AU  - Cordova P
AD  - Facultad de Farmacia, Universidad de Concepcion, Barrio Universitario, 4030000, 
      Concepcion, Chile.
FAU - Fernandez, Pola
AU  - Fernandez P
AD  - Facultad de Farmacia, Universidad de Concepcion, Barrio Universitario, 4030000, 
      Concepcion, Chile.
FAU - Lopez, Mariela
AU  - Lopez M
AD  - Facultad de Farmacia, Universidad de Concepcion, Barrio Universitario, 4030000, 
      Concepcion, Chile.
FAU - Villa, Lorenzo A
AU  - Villa LA
AD  - Facultad de Farmacia, Universidad de Concepcion, Barrio Universitario, 4030000, 
      Concepcion, Chile.
FAU - Morales, Felipe
AU  - Morales F
AD  - Facultad de Farmacia, Universidad de Concepcion, Barrio Universitario, 4030000, 
      Concepcion, Chile. felimora@udec.cl.
LA  - eng
PT  - Journal Article
DEP - 20150526
PL  - Netherlands
TA  - Int J Clin Pharm
JT  - International journal of clinical pharmacy
JID - 101554912
RN  - 0 (Antihypertensive Agents)
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (Hypoglycemic Agents)
RN  - 0 (hemoglobin A1c protein, human)
SB  - IM
MH  - Antihypertensive Agents/administration & dosage/therapeutic use
MH  - Blood Pressure/drug effects
MH  - Chile
MH  - Chronic Disease
MH  - Diabetes Mellitus, Type 2/*complications/*drug therapy/psychology
MH  - Female
MH  - Glycated Hemoglobin/drug effects
MH  - Health Knowledge, Attitudes, Practice
MH  - Humans
MH  - Hypertension/*complications/*drug therapy/psychology
MH  - Hypoglycemic Agents/administration & dosage/therapeutic use
MH  - Male
MH  - *Medication Adherence
MH  - Middle Aged
MH  - Patient Education as Topic/*methods
MH  - *Pharmacists
MH  - *Professional Role
MH  - Prospective Studies
OTO - NOTNLM
OT  - Chile
OT  - Medication adherence
OT  - Patient education
OT  - Pharmacotherapeutic optimization plan
EDAT- 2015/05/27 06:00
MHDA- 2016/09/02 06:00
CRDT- 2015/05/27 06:00
PHST- 2014/12/15 00:00 [received]
PHST- 2015/05/05 00:00 [accepted]
PHST- 2015/05/27 06:00 [entrez]
PHST- 2015/05/27 06:00 [pubmed]
PHST- 2016/09/02 06:00 [medline]
AID - 10.1007/s11096-015-0131-2 [pii]
AID - 10.1007/s11096-015-0131-2 [doi]
PST - ppublish
SO  - Int J Clin Pharm. 2015 Oct;37(5):734-8. doi: 10.1007/s11096-015-0131-2. Epub 2015 
      May 26.