PMID- 26009557 OWN - NLM STAT- MEDLINE DCOM- 20161213 LR - 20221207 IS - 1554-6063 (Electronic) IS - 0145-7217 (Print) IS - 0145-7217 (Linking) VI - 41 IP - 4 DP - 2015 Aug TI - Assessing the effectiveness of pharmacist-directed medication therapy management in improving diabetes outcomes in patients with poorly controlled diabetes. PG - 459-65 LID - 10.1177/0145721715587563 [doi] AB - PURPOSE: The purpose of this study was to compare medication adherence rates and type 2 diabetes mellitus (T2DM) health outcomes in a sample of underserved patients with suboptimally controlled T2DM (A1C >7%) who had received pharmacist-directed medication therapy management (MTM) to those who had not received MTM. METHODS: A retrospective review of 100 patient records was conducted. For the MTM group, a pharmacist engaged patients in patient-centered services to optimize therapeutic outcomes. Non-MTM patients received usual care. Outcomes were A1C, medication adherence, blood pressure, lipids, and creatinine. Group comparisons on clinical outcomes were analyzed before and after matching MTM and non-MTM patients on demographic characteristics. RESULTS: Before matching, the MTM group had a higher rate of medication adherence than the non-MTM group. The A1C levels were lower in the MTM group compared to the non-MTM group. Similarly, low-density lipoprotein (LDL) cholesterol was lower in the MTM group compared to the non-MTM group. After matching, medication adherence rate remained higher in the MTM group than the non-MTM group. Similarly, A1C levels remained lower in the MTM group than the non-MTM group. CONCLUSIONS: There is a paucity of research focused on behavioral interventions for improving health outcomes in underserved communities. Our results advance the existing literature by demonstrating a positive association between pharmacist-directed MTM, medication adherence, and glycemic control in a sample of underserved patients with suboptimally controlled T2DM. A prospective pharmacy intervention and examination of long-term effects of MTM on medication adherence and T2DM health outcomes in this population is warranted. CI - (c) 2015 The Author(s). FAU - Skinner, Jeannine S AU - Skinner JS AD - Meharry-Vanderbilt Alliance, Vanderbilt University Medical Center, Nashville, Tennessee (Dr Skinner, Mr Poe, Dr Boyer, Dr Wilkins) FAU - Poe, Brett AU - Poe B AD - Meharry-Vanderbilt Alliance, Vanderbilt University Medical Center, Nashville, Tennessee (Dr Skinner, Mr Poe, Dr Boyer, Dr Wilkins) FAU - Hopper, Rebecca AU - Hopper R AD - Saint Thomas Family Center, West, Nashville, Tennessee (Dr Hopper) FAU - Boyer, Alaina AU - Boyer A AD - Meharry-Vanderbilt Alliance, Vanderbilt University Medical Center, Nashville, Tennessee (Dr Skinner, Mr Poe, Dr Boyer, Dr Wilkins) FAU - Wilkins, Consuelo H AU - Wilkins CH AD - Meharry-Vanderbilt Alliance, Vanderbilt University Medical Center, Nashville, Tennessee (Dr Skinner, Mr Poe, Dr Boyer, Dr Wilkins) AD - Meharry Medical College, Nashville, Tennessee (Dr Wilkins) LA - eng GR - P30 DK092986/DK/NIDDK NIH HHS/United States GR - U54 MD007593/MD/NIMHD NIH HHS/United States GR - UL1 TR000445/TR/NCATS NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20150525 PL - United States TA - Diabetes Educ JT - The Diabetes educator JID - 7701401 RN - 0 (Glycated Hemoglobin A) RN - 0 (Hypoglycemic Agents) RN - 0 (Lipids) RN - 0 (hemoglobin A1c protein, human) RN - AYI8EX34EU (Creatinine) MH - Aged MH - Blood Pressure MH - Case-Control Studies MH - Creatinine/blood MH - Diabetes Mellitus, Type 2/blood/*drug therapy/psychology MH - Female MH - Glycated Hemoglobin/analysis MH - Humans MH - Hypoglycemic Agents/*administration & dosage MH - Lipids/blood MH - Male MH - Medication Adherence MH - *Medication Therapy Management MH - Middle Aged MH - *Pharmaceutical Services MH - Pharmacists MH - *Program Evaluation MH - Retrospective Studies PMC - PMC4504766 MID - NIHMS696203 EDAT- 2015/05/27 06:00 MHDA- 2016/12/15 06:00 PMCR- 2016/08/01 CRDT- 2015/05/27 06:00 PHST- 2015/05/27 06:00 [entrez] PHST- 2015/05/27 06:00 [pubmed] PHST- 2016/12/15 06:00 [medline] PHST- 2016/08/01 00:00 [pmc-release] AID - 0145721715587563 [pii] AID - 10.1177/0145721715587563 [doi] PST - ppublish SO - Diabetes Educ. 2015 Aug;41(4):459-65. doi: 10.1177/0145721715587563. Epub 2015 May 25.