PMID- 26010331
OWN - NLM
STAT- MEDLINE
DCOM- 20171106
LR  - 20181202
IS  - 1520-5711 (Electronic)
IS  - 1054-3406 (Linking)
VI  - 26
IP  - 3
DP  - 2016
TI  - Binary classification using multivariate receiver operating characteristic curve 
      for continuous data.
PG  - 421-31
LID - 10.1080/10543406.2015.1052479 [doi]
AB  - The classification scenario needs handling of more than one biomarker. The main 
      objective of the work is to propose a multivariate receiver operating 
      characteristic (MROC) model which linearly combines the markers to classify them 
      into one of the two groups and also to determine an optimal cut point. Simulation 
      studies are conducted for four sets of mean vectors and covariance matrices and a 
      real dataset is also used to demonstrate the proposed model. Linear and quadratic 
      discriminant analysis has also been applied to the above datasets in order to 
      explain the ease of the proposed model. Bootstrapped estimates of the parameters 
      of the ROC curve are also estimated.
FAU - Sameera, G
AU  - Sameera G
AD  - a Department of Statistics , Pondicherry University , Pondicherry , India.
FAU - Vardhan, R Vishnu
AU  - Vardhan RV
AD  - a Department of Statistics , Pondicherry University , Pondicherry , India.
FAU - Sarma, K V S
AU  - Sarma KV
AD  - b Department of Statistics , Sri Venkateswara University , Tirupati , India.
LA  - eng
PT  - Journal Article
DEP - 20150526
PL  - England
TA  - J Biopharm Stat
JT  - Journal of biopharmaceutical statistics
JID - 9200436
RN  - 0 (Biomarkers)
SB  - IM
MH  - Biomarkers/*analysis
MH  - Humans
MH  - Liver Diseases/diagnosis
MH  - Models, Statistical
MH  - *ROC Curve
OTO - NOTNLM
OT  - AUC
OT  - MROC
OT  - Optimal cutoff
EDAT- 2015/05/27 06:00
MHDA- 2017/11/07 06:00
CRDT- 2015/05/27 06:00
PHST- 2015/05/27 06:00 [entrez]
PHST- 2015/05/27 06:00 [pubmed]
PHST- 2017/11/07 06:00 [medline]
AID - 10.1080/10543406.2015.1052479 [doi]
PST - ppublish
SO  - J Biopharm Stat. 2016;26(3):421-31. doi: 10.1080/10543406.2015.1052479. Epub 2015 
      May 26.