PMID- 26016811
OWN - NLM
STAT- MEDLINE
DCOM- 20161006
LR  - 20181113
IS  - 1435-702X (Electronic)
IS  - 0721-832X (Linking)
VI  - 254
IP  - 3
DP  - 2016 Mar
TI  - Correlation between visual acuity changes and optical coherence tomography 
      morphological findings in idiopathic epiretinal membranes.
PG  - 437-44
LID - 10.1007/s00417-015-3069-0 [doi]
AB  - PURPOSE: To analyze the influence of spectral-domain optical coherence tomography 
      (SD-OCT) features on visual acuity changes in patients with idiopathic epiretinal 
      membranes (ERMs). METHODS: Seventy-nine eyes of 71 patients were included in this 
      study. SD-OCT was performed for all patients; data were collected upon ERM 
      diagnosis and at the final visit. The patients were divided into subgroups based 
      on their SD-OCT features. The initial best corrected visual acuity (BCVA) and 
      changes in BCVA for each subgroup were compared. A multivariate analysis was 
      performed to assess the factors associated with changes in BCVA. RESULTS: During 
      a mean follow-up period of 20.78 months, the mean change in logMAR visual acuity 
      was 0.052 +/- 0.089. Eyes with inner segment/outer segment (IS/OS) junction 
      disruption and cystoid macular edema (CME) had a significantly lower mean initial 
      BCVA than those without disruption and CME (P = 0.036 and P = 0.012, 
      respectively). However, only eyes with CME had significant changes in BCVA 
      (P = .034). Multivariate analysis revealed the presence of CME as the only factor 
      that had a significant correlation with VA changes. CONCLUSIONS: In patients with 
      idiopathic ERMs, the presence of CME and IS/OS disruption detected by OCT 
      correlated with a poorer initial BCVA. Most patients' visual acuity remained 
      stable during follow-up. The presence of CME with OCT represented a predictor of 
      the progression of visual acuity. These results may provide valuable clinical 
      information regarding the management of patients with idiopathic ERMs. We 
      demonstrated that the presence of CME and IS/OS disruption detected with OCT 
      correlated with a poorer BCVA in idiopathic ERMs. The visual acuity of most 
      patients was stable during the follow-up period. The presence of CME in OCT 
      represented a predictor of vision deterioration for patients with idiopathic 
      ERMs.
FAU - Fang, I-Mo
AU  - Fang IM
AD  - Department of Ophthalmology, Taipei City Hospital, Zhongxiao Branch, No. 87, 
      Tonde Road, Nankang District, Taipei, Taiwan. DAH75@tpech.gov.tw.
AD  - Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan. 
      DAH75@tpech.gov.tw.
FAU - Hsu, Chih-Chao
AU  - Hsu CC
AD  - Department of Ophthalmology, Taipei City Hospital, Zhongxiao Branch, No. 87, 
      Tonde Road, Nankang District, Taipei, Taiwan.
FAU - Chen, Li-Li
AU  - Chen LL
AD  - Department of Ophthalmology, Taipei City Hospital, Zhongxiao Branch, No. 87, 
      Tonde Road, Nankang District, Taipei, Taiwan.
LA  - eng
PT  - Journal Article
DEP - 20150529
PL  - Germany
TA  - Graefes Arch Clin Exp Ophthalmol
JT  - Graefe's archive for clinical and experimental ophthalmology = Albrecht von 
      Graefes Archiv fur klinische und experimentelle Ophthalmologie
JID - 8205248
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Epiretinal Membrane/*diagnosis/physiopathology
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Macular Edema/*diagnosis/physiopathology
MH  - Male
MH  - Middle Aged
MH  - Retinal Photoreceptor Cell Inner Segment/*pathology
MH  - Retinal Photoreceptor Cell Outer Segment/*pathology
MH  - Retrospective Studies
MH  - Tomography, Optical Coherence
MH  - Visual Acuity/*physiology
OTO - NOTNLM
OT  - Cystoid macular edema
OT  - Idiopathic epiretinal membrane
OT  - Optical coherent tomography
EDAT- 2015/05/29 06:00
MHDA- 2016/10/08 06:00
CRDT- 2015/05/29 06:00
PHST- 2015/02/23 00:00 [received]
PHST- 2015/05/15 00:00 [accepted]
PHST- 2015/05/05 00:00 [revised]
PHST- 2015/05/29 06:00 [entrez]
PHST- 2015/05/29 06:00 [pubmed]
PHST- 2016/10/08 06:00 [medline]
AID - 10.1007/s00417-015-3069-0 [pii]
AID - 10.1007/s00417-015-3069-0 [doi]
PST - ppublish
SO  - Graefes Arch Clin Exp Ophthalmol. 2016 Mar;254(3):437-44. doi: 
      10.1007/s00417-015-3069-0. Epub 2015 May 29.