PMID- 26025691 OWN - NLM STAT- MEDLINE DCOM- 20161213 LR - 20221207 IS - 1460-2393 (Electronic) IS - 1460-2393 (Linking) VI - 109 IP - 3 DP - 2016 Mar TI - Symptom-to-door times in patients presenting with ST elevation myocardial infarction--do ethnic or gender differences exist? PG - 175-80 LID - 10.1093/qjmed/hcv112 [doi] AB - BACKGROUND: Studies have shown higher in-hospital mortality for female patients and ethnic minorities admitted to hospital with acute ST elevation myocardial infarction (STEMI). Pre-hospital delay is thought to be associated with increased in-hospital mortality. AIM: To assess the impact of gender and ethnicity on symptom-to-door time (STDT) in patients presenting with STEMI. DESIGN: Retrospective survey of consecutive patients receiving primary percutaneous coronary intervention between January 2008 and January 2013. A multivariate model was used to adjust for confounders. MAIN OUTCOME MEASURE: Influence of gender and ethnicity on STDT. RESULTS: We analysed 1020 patients (75% male, 263 South Asians, 38 Afro Caribbeans and 719 White Europeans.) There was a trend towards longer unadjusted median STDT in women compared with men (132 min vs. 113 min P = 0.07) which disappeared after correction for age and ethnicity (P = 0.15). There was no gender difference in hospital mortality after correction for age (odds ratio 0.69, 95% confidence interval 0.40-1.18, P = 0.17). On linear regression analysis South Asians showed a trend towards longer STDT than other ethnic groups (P = 0.08) however after adjustment for diabetes there was no association between South Asian ethnicity and hospital mortality. CONCLUSIONS: Neither female gender nor ethnicity were shown to be associated with significant pre-hospital delay. CI - (c) The Author 2015. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oup.com. FAU - Brown, Richard A AU - Brown RA AD - From the University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, UK and. FAU - Shantsila, Eduard AU - Shantsila E AD - From the University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, UK and Cardiology Department at Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Birmingham and Sandwell Hospital, West Bromwich, UK. FAU - Varma, Chetan AU - Varma C AD - Cardiology Department at Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Birmingham and Sandwell Hospital, West Bromwich, UK. FAU - Lip, Gregory Y H AU - Lip GY AD - From the University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, UK and Cardiology Department at Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Birmingham and Sandwell Hospital, West Bromwich, UK richardbrown4@nhs.net. LA - eng PT - Journal Article PT - Multicenter Study PT - Observational Study DEP - 20150528 PL - England TA - QJM JT - QJM : monthly journal of the Association of Physicians JID - 9438285 SB - IM MH - Adult MH - Aged MH - Asian People/statistics & numerical data MH - Black People/statistics & numerical data MH - England/epidemiology MH - Female MH - Hospital Mortality MH - Hospitalization/statistics & numerical data MH - Humans MH - Male MH - Middle Aged MH - Percutaneous Coronary Intervention MH - Retrospective Studies MH - Risk Factors MH - ST Elevation Myocardial Infarction/*ethnology/*therapy MH - Sex Factors MH - Time Factors MH - Time-to-Treatment/statistics & numerical data MH - Treatment Outcome MH - White People/statistics & numerical data EDAT- 2015/05/31 06:00 MHDA- 2016/12/15 06:00 CRDT- 2015/05/31 06:00 PHST- 2015/03/13 00:00 [received] PHST- 2015/05/31 06:00 [entrez] PHST- 2015/05/31 06:00 [pubmed] PHST- 2016/12/15 06:00 [medline] AID - hcv112 [pii] AID - 10.1093/qjmed/hcv112 [doi] PST - ppublish SO - QJM. 2016 Mar;109(3):175-80. doi: 10.1093/qjmed/hcv112. Epub 2015 May 28.