PMID- 26046031 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20150605 LR - 20201001 IS - 2288-6478 (Print) IS - 2288-6761 (Electronic) IS - 2288-6478 (Linking) VI - 21 IP - 1 DP - 2015 Apr TI - New antiresorptive therapies for postmenopausal osteoporosis. PG - 1-11 LID - 10.6118/jmm.2015.21.1.1 [doi] AB - Osteoporosis is a systemic skeletal disease whose risk increases with age and it is common among postmenopausal women. Currently, almost all pharmacological agents for osteoporosis target the bone resorption component of bone remodeling activity. Current antiresorptive agents are effective, but the effectiveness of some agents is limited by real or perceived intolerance, longterm adverse events (AEs), coexisting comorbidities, and inadequate long-term adherence. New antiresorptive therapies that may expand options for the prevention and treatment of osteoporosis include denosumab, combination of conjugated estrogen/bazedoxifene and cathepsin K inhibitors. However, the long-term efficacy and AEs of these antiresorptive therapies need to be confirmed in studies with a longer follow-up period. FAU - Choi, Hee-Jeong AU - Choi HJ AD - Department of Family Medicine, Eulji University School of Medicine, Daejeon, Korea. LA - eng PT - Journal Article PT - Review DEP - 20150427 PL - Korea (South) TA - J Menopausal Med JT - Journal of menopausal medicine JID - 101632648 PMC - PMC4452807 OTO - NOTNLM OT - Bone density conservation agents OT - Fractures bone OT - Osteoporosis OT - Postmenopause COIS- Conflict of Interest: No potential conflict of interest relevant to this article was reported. EDAT- 2015/06/06 06:00 MHDA- 2015/06/06 06:01 PMCR- 2015/04/01 CRDT- 2015/06/06 06:00 PHST- 2015/02/22 00:00 [received] PHST- 2015/03/19 00:00 [revised] PHST- 2015/03/25 00:00 [accepted] PHST- 2015/06/06 06:00 [entrez] PHST- 2015/06/06 06:00 [pubmed] PHST- 2015/06/06 06:01 [medline] PHST- 2015/04/01 00:00 [pmc-release] AID - 10.6118/jmm.2015.21.1.1 [doi] PST - ppublish SO - J Menopausal Med. 2015 Apr;21(1):1-11. doi: 10.6118/jmm.2015.21.1.1. Epub 2015 Apr 27.