PMID- 26046666
OWN - NLM
STAT- MEDLINE
DCOM- 20151005
LR  - 20151119
IS  - 1532-5415 (Electronic)
IS  - 0002-8614 (Linking)
VI  - 63
IP  - 7
DP  - 2015 Jul
TI  - Values of the Minimal Clinically Important Difference for the Neuropsychiatric 
      Inventory Questionnaire in Individuals with Dementia.
PG  - 1448-52
LID - 10.1111/jgs.13473 [doi]
AB  - OBJECTIVES: To estimate the minimal clinically important difference (MCID) for 
      the Neuropsychiatric Inventory Questionnaire (NPI-Q), a widely used measure of 
      behavioral and psychological symptoms of dementia (BPSDs) and associated 
      caregiver stress. DESIGN: Ten registered nurses rated the severity of BPSDs and 
      caregiver distress using the NPI-Q during six monthly assessments and an external 
      reference, a 7-point Likert-type global rating of BPSDs change during five 
      monthly assessments from the second to the sixth month. An anchor-based (global 
      ratings of change) approach and a distribution-based (standard error of 
      measurement) approach were used to determine the MCID for the NPI-Q severity and 
      distress subscales. SETTING: Long-term care facility. PARTICIPANTS: Nonbedridden 
      residents with dementia (n = 45) and registered nurses (n = 10). MEASUREMENTS: 
      NPI-Q (severity and caregiver distress subscales) and global ratings of changes 
      in BPSDs on a 7-point Likert-type scale. RESULTS: The NPI-Q MCID ranges were 2.77 
      to 3.18 for severity and 3.10 to 3.95 for distress. Residents in the highest 
      NPI-Q tertile at baseline had higher MCID severity (3.62) and distress (5.08) 
      scores than those in the lowest tertile (severity (2.40), distress (3.10)). 
      CONCLUSION: This study provides an estimate of the MCID for severity and distress 
      subscales of the NPI-Q, which can help clinicians and researchers determine 
      whether NPI-Q change scores within a group of individuals with dementia are 
      beyond measurement error and are clinically important.
CI  - (c) 2015, Copyright the Authors Journal compilation (c) 2015, The American Geriatrics 
      Society.
FAU - Mao, Hui-Fen
AU  - Mao HF
AD  - School of Occupational Therapy, College of Medicine, National Taiwan University, 
      Taipei, Taiwan.
FAU - Kuo, Chun-An
AU  - Kuo CA
AD  - School of Occupational Therapy, College of Medicine, National Taiwan University, 
      Taipei, Taiwan.
FAU - Huang, Wen-Ni
AU  - Huang WN
AD  - Department of Physical Therapy, I-Shou University, Kaohsiung City, Taiwan.
FAU - Cummings, Jeffrey L
AU  - Cummings JL
AD  - Cleveland Clinic, Las Vegas, Nevada.
FAU - Hwang, Tzung-Jeng
AU  - Hwang TJ
AUID- ORCID: 0000-0001-7894-9484
AD  - Department of Psychiatry, National Taiwan University Hospital and College of 
      Medicine, National Taiwan University, Taipei, Taiwan.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20150605
PL  - United States
TA  - J Am Geriatr Soc
JT  - Journal of the American Geriatrics Society
JID - 7503062
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Caregivers/*psychology
MH  - Dementia/*psychology
MH  - Female
MH  - Humans
MH  - Long-Term Care
MH  - Male
MH  - *Neuropsychological Tests
MH  - Psychometrics
MH  - Reproducibility of Results
MH  - Severity of Illness Index
MH  - Surveys and Questionnaires
MH  - Taiwan
OTO - NOTNLM
OT  - Neuropsychiatric Inventory Questionnaire (NPI-Q)
OT  - behavioral and psychological symptoms of dementia (BPSDs)
OT  - dementia
OT  - minimal clinically important difference
EDAT- 2015/06/06 06:00
MHDA- 2015/10/06 06:00
CRDT- 2015/06/06 06:00
PHST- 2015/06/06 06:00 [entrez]
PHST- 2015/06/06 06:00 [pubmed]
PHST- 2015/10/06 06:00 [medline]
AID - 10.1111/jgs.13473 [doi]
PST - ppublish
SO  - J Am Geriatr Soc. 2015 Jul;63(7):1448-52. doi: 10.1111/jgs.13473. Epub 2015 Jun 
      5.