PMID- 26047589 OWN - NLM STAT- MEDLINE DCOM- 20161213 LR - 20161230 IS - 1532-8635 (Electronic) IS - 1524-9042 (Linking) VI - 16 IP - 4 DP - 2015 Aug TI - Registered Nurses' Knowledge about Adverse Effects of Analgesics when Treating Postoperative Pain in Patients with Dementia. PG - 544-51 LID - S1524-9042(14)00163-5 [pii] LID - 10.1016/j.pmn.2014.10.003 [doi] AB - Registered nurses (RNs) play a pivotal role in treating pain and preventing and recognizing the adverse effects (AEs) of analgesics in patients with dementia. The purpose of this study was to determine RNs' knowledge of potentially clinically relevant AEs of analgesics. A descriptive, cross-sectional study design was used. In all, 267 RNs treating orthopedic patients, including patients with dementia, in 7 university hospitals and 10 central hospitals in Finland, completed a questionnaire. Analgesics were defined according to the Anatomic Therapeutic Classification as strong opioids, weak opioids, nonsteroidal anti-inflammatory analgesics (NSAIDs), and paracetamol. Definitions of AEs were based on the literature. Logistic regression analysis was applied to analyze which variables predicted nurses' knowledge. The RNs had a clear understanding of the AEs of paracetamol and strong opioids. However, the AEs of NSAIDs, especially renal and cardiovascular AEs, were less well known. The median percentage of correct answers was 87% when asked about strong opioids, 73% for weak opioids, and 60% for NSAIDs. Younger RNs had better knowledge of opioid-related AEs (odds ratio [OR] per 1-year increase, 0.97; 95% confidence interval [CI], 0.94-1.00) and weak opioids (OR, 0.96; 95% CI, 0.93-0.99). This study provides evidence of a deficiency in RNs' knowledge, especially regarding the adverse renal and cardiovascular effects of NSAIDs. Such lack of knowledge indicates that hospitals may need to update the knowledge of older RNs, especially those who treat vulnerable patients with dementia. CI - Copyright (c) 2015 American Society for Pain Management Nursing. Published by Elsevier Inc. All rights reserved. FAU - Rantala, Maija AU - Rantala M AD - Department of Nursing Science, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland. Electronic address: maija.rantala@live.com. FAU - Hartikainen, Sirpa AU - Hartikainen S AD - School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland. FAU - Kvist, Tarja AU - Kvist T AD - Department of Nursing Science, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland. FAU - Kankkunen, Paivi AU - Kankkunen P AD - Department of Nursing Science, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20150602 PL - United States TA - Pain Manag Nurs JT - Pain management nursing : official journal of the American Society of Pain Management Nurses JID - 100890606 RN - 0 (Analgesics) RN - 0 (Analgesics, Opioid) RN - 0 (Anti-Inflammatory Agents, Non-Steroidal) RN - 16978-57-7 (dexamethasone-21-sulfobenzoate) RN - 362O9ITL9D (Acetaminophen) RN - 7S5I7G3JQL (Dexamethasone) SB - IM MH - Acetaminophen/adverse effects MH - Adult MH - Age Factors MH - Analgesics/adverse effects MH - Analgesics, Opioid/*adverse effects MH - Anti-Inflammatory Agents, Non-Steroidal/*adverse effects MH - *Clinical Competence MH - Cross-Sectional Studies MH - Dementia/*complications MH - Dexamethasone/analogs & derivatives MH - Female MH - Finland MH - Hospitals, University MH - Humans MH - Logistic Models MH - Male MH - Middle Aged MH - Nurses/*standards MH - Nursing Staff, Hospital/*standards MH - *Orthopedic Procedures MH - Pain, Postoperative/complications/*drug therapy MH - Surveys and Questionnaires EDAT- 2015/06/07 06:00 MHDA- 2016/12/15 06:00 CRDT- 2015/06/07 06:00 PHST- 2014/02/10 00:00 [received] PHST- 2014/10/07 00:00 [revised] PHST- 2014/10/10 00:00 [accepted] PHST- 2015/06/07 06:00 [entrez] PHST- 2015/06/07 06:00 [pubmed] PHST- 2016/12/15 06:00 [medline] AID - S1524-9042(14)00163-5 [pii] AID - 10.1016/j.pmn.2014.10.003 [doi] PST - ppublish SO - Pain Manag Nurs. 2015 Aug;16(4):544-51. doi: 10.1016/j.pmn.2014.10.003. Epub 2015 Jun 2.