PMID- 26048603
OWN - NLM
STAT- MEDLINE
DCOM- 20150803
LR  - 20161125
IS  - 0028-3843 (Print)
IS  - 0028-3843 (Linking)
VI  - 49
IP  - 3
DP  - 2015
TI  - Non-paraganglioma tumors of the jugular foramen - Growth patterns, radiological 
      presentation, differential diagnosis.
PG  - 156-63
LID - S0028-3843(15)00059-6 [pii]
LID - 10.1016/j.pjnns.2015.04.003 [doi]
AB  - OBJECTIVE: Most common tumors of the jugular foramen are paragangliomas. However, 
      other lesions, also malignant, may involve the jugular foramen and mimic 
      radiographic presentation of paragangliomas. Therefore, a correct preoperative 
      diagnosis is crucial for best treatment planning. This study analyzes imaging 
      characteristics of non-paraganglioma neoplasms involving the jugular foramen, 
      with attention given to features helpful in differential diagnosis. STUDY DESIGN: 
      A retrospective chart search. SETTING: Teritary referral university centre. 
      SUBJECTS AND METHODS: During the years 1997-2010, 11 cases of jugular foramen 
      tumors other than paragangliomas, with available imaging studies, were 
      identified. Histopathology revealed: 3 schwannomas, 1 malignant schwannoma, 2 
      meningiomas, 1 hemangiopericytoma, 1 ependymoma, 1 endolymphatic sac carcinoma 
      (ELST) and 2 nasopharyngeal carcinoma metastases. CT, MRI and angiography were 
      assessed to determine tumor growth directions, bone involvement, tumor morphology 
      and vascular composition. RESULTS: Schwannomas were characterized by 
      parapharyngeal space involvement, jugular foramen expansion, preservation of 
      cortical margins, irregular contrast enhancement. Meningiomas presented diffuse 
      bone infiltration, sclerotic changes, erosion of the cortical bone. Ependymoma 
      showed diffuse skull base infiltration, permeative erosion, heterogeneity, 
      abundant vascularization. Hemangiopericytoma radiologically imitated 
      paraganglioma. ELST showed permeative/geographic bony destruction, heterogeneity, 
      intratumoral bony fragments. Metastases were lytic, solid lesions characterized 
      by circumferential growth, internal carotid artery encasement and stenosis. 
      CONCLUSIONS: A combination of certain radiological features including tumor 
      epicenter, growth vectors, skull base infiltration, bony changes and tumor 
      morphology help establish correct preoperative diagnosis and differentiate less 
      common jugular foramen tumors, from most common paragangliomas. 
      Hemangiopericytoma may radiologically mimic paraganglioma.
CI  - Copyright (c) 2015 Polish Neurological Society. Published by Elsevier Urban & 
      Partner Sp. z o.o. All rights reserved.
FAU - Szymanska, A
AU  - Szymanska A
AD  - Department of Interventional Radiology and Neuroradiology, Medical University of 
      Lublin, Lublin, Poland.
FAU - Szymanski, M
AU  - Szymanski M
AD  - Department of Otolaryngology, Medical University of Lublin, Lublin, Poland. 
      Electronic address: marcinszym@poczta.onet.pl.
FAU - Czekajska-Chehab, E
AU  - Czekajska-Chehab E
AD  - Department of Radiology, Medical University of Lublin, Lublin, Poland.
FAU - Szczerbo-Trojanowska, M
AU  - Szczerbo-Trojanowska M
AD  - Department of Interventional Radiology and Neuroradiology, Medical University of 
      Lublin, Lublin, Poland.
LA  - eng
PT  - Journal Article
DEP - 20150423
PL  - Poland
TA  - Neurol Neurochir Pol
JT  - Neurologia i neurochirurgia polska
JID - 0101265
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Diagnosis, Differential
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Radiography
MH  - Skull Base Neoplasms/*diagnosis/diagnostic imaging/*pathology
MH  - Young Adult
OTO - NOTNLM
OT  - Angiography
OT  - CT
OT  - Jugular foramen
OT  - MRI
OT  - Tumor
EDAT- 2015/06/07 06:00
MHDA- 2015/08/04 06:00
CRDT- 2015/06/07 06:00
PHST- 2015/01/11 00:00 [received]
PHST- 2015/03/29 00:00 [revised]
PHST- 2015/04/13 00:00 [accepted]
PHST- 2015/06/07 06:00 [entrez]
PHST- 2015/06/07 06:00 [pubmed]
PHST- 2015/08/04 06:00 [medline]
AID - S0028-3843(15)00059-6 [pii]
AID - 10.1016/j.pjnns.2015.04.003 [doi]
PST - ppublish
SO  - Neurol Neurochir Pol. 2015;49(3):156-63. doi: 10.1016/j.pjnns.2015.04.003. Epub 
      2015 Apr 23.