PMID- 26055907
OWN - NLM
STAT- MEDLINE
DCOM- 20160304
LR  - 20181113
IS  - 1862-1783 (Electronic)
IS  - 1673-1581 (Print)
IS  - 1673-1581 (Linking)
VI  - 16
IP  - 6
DP  - 2015 Jun
TI  - Influence of dietary taurine and housing density on oviduct function in laying 
      hens.
PG  - 456-64
LID - 10.1631/jzus.B1400256 [doi]
AB  - Experiments were conducted to study the effects of dietary taurine and housing 
      density on oviduct function in laying hens. Green-shell laying hens were randomly 
      assigned to a free range group and two caged groups, one with low-density and the 
      other with high-density housing. Each group was further divided into control (C) 
      and taurine treatment (T) groups. All hens were fed the same basic diet except 
      that the T groups' diet was supplemented with 0.1% taurine. The experiment lasted 
      15 d. Survival rates, laying rates, daily feed consumption, and daily weight gain 
      were recorded. Histological changes, inflammatory mediator levels, and oxidation 
      and anti-oxidation levels were determined. The results show that dietary taurine 
      supplementation and reduced housing density significantly attenuated 
      pathophysiological changes in the oviduct. Nuclear factor-kappaB (NF-kappaB) DNA binding 
      activity increased significantly in the high-density housing group compared with 
      the two other housing groups and was reduced by taurine supplementation. Tumor 
      necrosis factor-alpha (TNF-alpha) mRNA expression in the high-density and low-density C 
      and T groups increased significantly. In the free range and low-density groups, 
      dietary taurine significantly reduced the expression of TNF-alpha mRNA. 
      Supplementation with taurine decreased interferon-gamma (IFN-gamma) mRNA expression 
      significantly in the low-density groups. Interleukin 4 (IL-4) mRNA expression was 
      significantly higher in caged hens. IL-10 mRNA expression was higher in the 
      high-density C group than in the free range and low-density C groups. 
      Supplementation with taurine decreased IL-10 mRNA expression significantly in the 
      high-density group and increased superoxide dismutase (SOD) activity in the free 
      range hens. We conclude that taurine has important protective effects against 
      oviduct damage. Reducing housing density also results in less oxidative stress, 
      less inflammatory cell infiltration, and lower levels of inflammatory mediators 
      in the oviduct. Therefore, both dietary taurine and reduced housing density can 
      ameliorate oviduct injury, enhance oviduct health, and promote egg production in 
      laying hens.
FAU - Dai, Bin
AU  - Dai B
AD  - College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, 
      China; Animal Husbandry and Veterinary Bureau of Dongyang, Dongyang 322100, 
      China; Poultry Institute, Chinese Academy of Agricultural Sciences, Yangzhou 
      225125, China.
FAU - Zhang, Yuan-shu
AU  - Zhang YS
FAU - Ma, Zi-li
AU  - Ma ZL
FAU - Zheng, Liu-hai
AU  - Zheng LH
FAU - Li, Shuang-jie
AU  - Li SJ
FAU - Dou, Xin-hong
AU  - Dou XH
FAU - Gong, Jian-sen
AU  - Gong JS
FAU - Miao, Jin-feng
AU  - Miao JF
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - J Zhejiang Univ Sci B
JT  - Journal of Zhejiang University. Science. B
JID - 101236535
RN  - 1EQV5MLY3D (Taurine)
SB  - IM
MH  - Administration, Oral
MH  - Animals
MH  - Chickens/*physiology
MH  - *Dietary Supplements
MH  - Female
MH  - *Housing, Animal
MH  - Oviducts/*physiology
MH  - Oviparity/*physiology
MH  - Taurine/administration & dosage/*metabolism
PMC - PMC4471597
OTO - NOTNLM
OT  - Inflammation
OT  - Laying hens
OT  - Oviduct injury
OT  - Rearing pattern
OT  - Taurine
COIS- Compliance with ethics guidelines: Bin DAI, Yuan-shu ZHANG, Zi-li MA, Liu-hai 
      ZHENG, Shuang-jie LI, Xin-hong DOU, Jian-sen GONG, and Jin-feng MIAO declare that 
      they have no conflict of interest. All institutional and national guidelines for 
      the care and use of laboratory animals were followed.
EDAT- 2015/06/10 06:00
MHDA- 2016/03/05 06:00
PMCR- 2015/06/01
CRDT- 2015/06/10 06:00
PHST- 2015/06/10 06:00 [entrez]
PHST- 2015/06/10 06:00 [pubmed]
PHST- 2016/03/05 06:00 [medline]
PHST- 2015/06/01 00:00 [pmc-release]
AID - 10.1631/jzus.B1400256 [doi]
PST - ppublish
SO  - J Zhejiang Univ Sci B. 2015 Jun;16(6):456-64. doi: 10.1631/jzus.B1400256.