PMID- 26056428
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150609
LR  - 20240323
IS  - 1177-5467 (Print)
IS  - 1177-5483 (Electronic)
IS  - 1177-5467 (Linking)
VI  - 9
DP  - 2015
TI  - Epidemiology of uveitis in the mid-Atlantic United States.
PG  - 889-901
LID - 10.2147/OPTH.S80972 [doi]
AB  - PURPOSE: To demonstrate the demographic, anatomic, and diagnostic classification 
      of patients with uveitis seen in a tertiary care center in central Virginia. 
      METHODS: Retrospective chart review of patient demographics, disease 
      characteristics, and disease severity-related outcomes (therapies, visual 
      outcomes, and complications) from 1984 to 2014. RESULTS: There were 491 patients 
      (644 eyes) with mean age of 46 years (+/-21.4 years) and mean duration of follow up 
      of 4.8 years (+/-6.8 years). Of these, 278 patients were female (56.6%). Further, 
      60.5% were Caucasian, and 27.3% were African American. The anatomic types seen 
      were anterior uveitis (67.3%), panuveitis (14.5%), posterior uveitis (12.6%), and 
      intermediate uveitis (5.3%). The most common etiology was post-traumatic (12.2%), 
      followed by post-procedural (10.0%), herpetic (7.9%), human leukocyte antigen 
      (HLA)-B27-associated (6.7%), and sarcoidosis (6.7%). Herpetic uveitis was more 
      common among Caucasians than African Americans (sex-adjusted odds ratio [OR]: 
      7.69, 95% confidence interval [CI] [2.12, 50.00]), and sarcoidosis was more 
      common among African Americans than Caucasians (sex-adjusted OR: 6.54, 95% CI 
      [2.98, 15.29]). Herpetic anterior uveitis was more common among females than 
      males (race-adjusted OR: 3.03, 95% CI [1.32, 7.71]). Multifocal choroiditis was 
      more common among males than females (race-adjusted OR: 9.09, 95% CI [1.47, 
      100.00]). Mean logMAR visual acuity was 0.18 at initial and final visit. A total 
      388 (79%) and 133 (27.3%) patients received local and systemic steroids, 
      respectively. A total 52 patients (10.6%) received an antimetabolite. A total 116 
      patients (23.7%) were managed with topical glaucoma medication. A total 43 
      (8.8%), 129 (26.4%), and 46 patients (9.4%) underwent glaucoma surgery, cataract 
      surgery, and vitrectomy, respectively. CONCLUSION: Over the period of this study, 
      Caucasian patients were more frequently seen than non-Caucasians, although 
      African Americans constituted a considerable size of study population. The most 
      common diagnoses were undifferentiated anterior uveitis, traumatic uveitis, 
      post-procedural uveitis, herpetic disease, HLA-B27 associated uveitis, and 
      sarcoidosis. Unlike previous reports, traumatic and post-procedural uveitis were 
      frequently reported. Mean visual acuity remained stable from initial to final 
      visit.
FAU - Bajwa, Asima
AU  - Bajwa A
AD  - Department of Ophthalmology, University of Virginia, Charlottesville, VA, USA.
FAU - Osmanzada, Diba
AU  - Osmanzada D
AD  - Department of Ophthalmology, University of Virginia, Charlottesville, VA, USA.
FAU - Osmanzada, Susan
AU  - Osmanzada S
AD  - Department of Ophthalmology, University of Virginia, Charlottesville, VA, USA.
FAU - Khan, Irfan
AU  - Khan I
AD  - Department of Ophthalmology, University of Virginia, Charlottesville, VA, USA.
FAU - Patrie, Jim
AU  - Patrie J
AD  - Department of Public Health Sciences, University of Virginia, Charlottesville, 
      VA, USA.
FAU - Xin, Wenjun
AU  - Xin W
AD  - Department of Public Health Sciences, University of Virginia, Charlottesville, 
      VA, USA.
FAU - Reddy, Ashvini K
AU  - Reddy AK
AD  - Department of Ophthalmology, University of Virginia, Charlottesville, VA, USA.
LA  - eng
PT  - Journal Article
DEP - 20150520
PL  - New Zealand
TA  - Clin Ophthalmol
JT  - Clinical ophthalmology (Auckland, N.Z.)
JID - 101321512
PMC - PMC4445955
OTO - NOTNLM
OT  - central Virginia
OT  - demographics
OT  - mid-Atlantic United States
EDAT- 2015/06/10 06:00
MHDA- 2015/06/10 06:01
PMCR- 2015/05/20
CRDT- 2015/06/10 06:00
PHST- 2015/06/10 06:00 [entrez]
PHST- 2015/06/10 06:00 [pubmed]
PHST- 2015/06/10 06:01 [medline]
PHST- 2015/05/20 00:00 [pmc-release]
AID - opth-9-889 [pii]
AID - 10.2147/OPTH.S80972 [doi]
PST - epublish
SO  - Clin Ophthalmol. 2015 May 20;9:889-901. doi: 10.2147/OPTH.S80972. eCollection 
      2015.